Revision history of "Pathogenesis driven by RNAs with expansion of trinucleotide repeats: mechanisms and therapeutic strategies" (Q84328)

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7 March 2024

6 July 2023

11 June 2023

24 May 2023

2 March 2023

25 October 2022

21 October 2022

27 September 2022

13 August 2022

  • curprev 17:1317:13, 13 August 2022DG Regio talk contribs 62,807 bytes +39,698 Changed label, description and/or aliases in et, lt, hr, el, sk, fi, hu, cs, lv, ga, sl, bg, mt, pt, da, ro, sv, nl, fr, de, it, es, and other parts: Adding translations: et, lt, hr, el, sk, fi, hu, cs, lv, ga, sl, bg, mt, pt, da, ro, sv,

19 January 2022

15 January 2022

16 December 2021

7 December 2021

30 November 2021

  • curprev 16:3316:33, 30 November 2021DG Regio talk contribs 14,492 bytes +2,112 Created claim: summary (P836): La dystrophie myotonique (DM) et le syndrome de Trémor-Ataxie Fragile associé aux X (FXTAS) sont des troubles dominants causés par le gain d’ARN de la fonction des répétitions CUG ou CGG élargies. Les deux ARN peuvent séquestrer les protéines nucléaires, et leurs séquences répétées subissent une traduction atypique en peptides acides mono-amino toxiques. Étant donné que la cible moléculaire causale est bien définie, les DM et les FXTAS sont très...
  • curprev 16:3316:33, 30 November 2021DG Regio talk contribs 12,380 bytes +195 Changed label, description and/or aliases in fr: translated_label

29 October 2020

14 October 2020

  • curprev 12:3612:36, 14 October 2020DG Regio talk contribs 12,625 bytes +166 Changed label, description and/or aliases in 1 language: translated_label
  • curprev 12:3612:36, 14 October 2020DG Regio talk contribs 12,459 bytes −170 Changed label, description and/or aliases in 1 language: remove_english_label
  • curprev 12:3612:36, 14 October 2020DG Regio talk contribs 12,629 bytes +1,819 Created claim: summary (P836): Myotonic Dystrophy (DM) and Fragile X-associated tremor-Ataxia Syndrome (FXTAS) are dominant disorders caused by RNA gain of function of expanded CUG or CGG repeats. Both RNAs may sequester nuclear proteins, and their repeat sequences Undergo untypical translation into toxic mono-amino acid peptides. Since the causative molecular target is well defined, DM and FXTAS are highly amenable to the development of RNA targeting therapy. We and others d...
  • curprev 12:3612:36, 14 October 2020DG Regio talk contribs 10,810 bytes −942 Removed claim: summary (P836): Myotoic Dystrophy (DM) and Fragile X-associated tremora-taxia Syndrome (FXTAS)Boh RNAS mat sequeaster nuclear protein, and their thereof.Since the cause of molecular target is well defined, DM and FXTAS are duly amending to the development of the development of RNA.And other, with a view to producing results, in animal models of DM;they are a new tool to reduce the effect of FAS to reduce its translation rate.Iim to achieve the gene that shall...

25 September 2020

23 September 2020

9 June 2020

7 June 2020

26 March 2020

4 March 2020

  • curprev 10:0710:07, 4 March 2020DG Regio talk contribs 10,477 bytes +942 Created claim: summary (P836): Myotoic Dystrophy (DM) and Fragile X-associated tremora-taxia Syndrome (FXTAS)Boh RNAS mat sequeaster nuclear protein, and their thereof.Since the cause of molecular target is well defined, DM and FXTAS are duly amending to the development of the development of RNA.And other, with a view to producing results, in animal models of DM;they are a new tool to reduce the effect of FAS to reduce its translation rate.Iim to achieve the gene that shall b...

18 February 2020

8 February 2020

31 January 2020

14 January 2020