Revision history of "2017 Research Allowances: Reactivation of dormant macrophages in tumours via inhibition of proprotein convertase PC1/3 coupled with the use of LLR receptor ligands (Macbeth)" (Q3688154)

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10 October 2024

  • curprev 00:3000:30, 10 October 2024DG Regio talk contribs 54,986 bytes −1 Changed label, description and/or aliases in pt
  • curprev 00:3000:30, 10 October 2024DG Regio talk contribs 54,987 bytes +17 Set a claim value: summary (P836): O projeto centra-se no desenvolvimento de uma estratégia terapêutica para reativar os macrófagos dentro dos tumores. O ambiente imunossupressor criado pelo tumor direcionará macrófagos para um fenótipo pró-tumoral. Em seguida, participarão no crescimento do tumor atuando diretamente nas células cancerígenas, mas também suprimindo as respostas citotóxicas dos linfócitos T, pelo que são um elemento fundamental do ambiente tumoral. O desafio é encontra...

12 March 2024

12 January 2024

19 June 2023

12 June 2023

8 June 2023

11 August 2022

  • curprev 19:3719:37, 11 August 2022DG Regio talk contribs 51,704 bytes +35,029 Changed label, description and/or aliases in et, lt, hr, el, sk, fi, pl, hu, cs, lv, ga, sl, bg, mt, pt, da, ro, sv, nl, fr, de, it, es, and other parts: Adding translations: et, lt, hr, el, sk, fi, pl, hu, cs, lv, ga, sl, bg, mt, pt, da, ro, sv,

14 January 2022

13 January 2022

6 December 2021

1 December 2021

  • curprev 09:0209:02, 1 December 2021DG Regio talk contribs 11,269 bytes +1,572 Created claim: summary (P836): Das Projekt konzentriert sich auf die Entwicklung einer therapeutischen Strategie zur Reaktivierung von Makrophagen in Tumoren. Die immunsuppressive Umgebung des Tumors wird Makrophagen auf einen pro-Tumor-Phänotyp lenken. Sie werden dann zum Tumorwachstum beitragen, indem sie direkt auf die Krebszellen einwirken, aber auch die zytotoxischen Reaktionen der T-Lymphozyten entfernen. Sie sind daher ein Schlüsselelement der Tumorumgebung. Die Herau...

27 November 2021

  • curprev 14:1414:14, 27 November 2021DG Regio talk contribs 9,697 bytes −1,629 Removed claim: summary (P836): Le projet porte sur le développement d’une stratégie thérapeutique permettant de réactiver les macrophages présents au sein des Tumeurs. L’environnement immunosuppresseur créé par la tumeur va orienter les macrophaages vers un phénotype pro-tumoral. ILS vont alors participer à la croissance de la tumeur en agissant directement sur les cellules cancéreuses mais aussi en supprimant les réponses cytotoxiques des lymphocytes T. Ils représententent...
  • curprev 00:1900:19, 27 November 2021DG Regio talk contribs 11,326 bytes +1,629 Created claim: summary (P836): Le projet porte sur le développement d’une stratégie thérapeutique permettant de réactiver les macrophages présents au sein des Tumeurs. L’environnement immunosuppresseur créé par la tumeur va orienter les macrophaages vers un phénotype pro-tumoral. ILS vont alors participer à la croissance de la tumeur en agissant directement sur les cellules cancéreuses mais aussi en supprimant les réponses cytotoxiques des lymphocytes T. Ils représententent d...

26 November 2021

24 November 2021

22 November 2021

  • curprev 10:1110:11, 22 November 2021DG Regio talk contribs 9,019 bytes +233 Changed label, description and/or aliases in en: translated_label
  • curprev 10:1110:11, 22 November 2021DG Regio talk contribs 8,786 bytes +1,489 Created claim: summary (P836): The project focuses on the development of a therapeutic strategy to reactivate macrophages within tumours. The immunosuppressive environment created by the tumor will direct macrophages towards a pro-tumoral phenotype. They will then participate in the growth of the tumour by acting directly on cancer cells but also by suppressing cytotoxic responses of T lymphocytes, so they are a key element of the tumour environment. The challenge is to find...

17 November 2021