Revision history of "Role of NKX2-3 homeobox protein in BCR/NF-kB signaling and cooperation with NOTCH in the development of marginal area lymphoma" (Q3204503)

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10 October 2024

  • curprev 10:0610:06, 10 October 2024DG Regio talk contribs 82,713 bytes +15 Set a claim value: summary (P836): Este projeto tem como objetivo avançar no conhecimento da biologia e terapia do linfoma de área marginal (LZM). Para isso, utilizaremos vários modelos murinos geneticamente modificados que induzem a LZM análoga à patologia humana (Robles, Nat Comm 2016). Descrevemos que a proteína homeobox NKX2-3 é expressa de forma aberrante em amostras de doentes com MLL, mas não noutros linfomas B. A ativação constitutiva do receptor de células B (BCR) e, por sua...

7 March 2024

20 December 2023

12 June 2023

10 June 2023

18 August 2022

  • curprev 10:4910:49, 18 August 2022DG Regio talk contribs 81,423 bytes +56,090 Changed label, description and/or aliases in el, da, fi, mt, lv, sk, ga, cs, pt, et, hu, bg, lt, hr, sv, ro, sl, pl, nl, fr, de, it, es, and other parts: Adding translations: el, da, fi, mt, lv, sk, ga, cs, pt, et, hu, bg, lt, hr, sv, ro, sl, pl,

16 January 2022

17 December 2021

9 December 2021

5 December 2021

13 October 2021

  • curprev 01:3301:33, 13 October 2021DG Regio talk contribs 13,309 bytes +186 Changed label, description and/or aliases in en: translated_label
  • curprev 01:3301:33, 13 October 2021DG Regio talk contribs 13,123 bytes +2,621 Created claim: summary (P836): This project aims to advance knowledge of the biology and therapy of marginal area lymphoma (LZM). For this we will use several genetically modified murine models that induce LZM analogous to human pathology (Robles, Nat Comm 2016). We have described that the NKX2-3 homeobox protein is aberrantly expressed in samples from patients with MLL but not in other B lymphomas. Constitutive activation of the B-cell receptor (BCR) and in turn of the NF-kB...

11 October 2021

10 October 2021

9 October 2021