Revision history of "Formaldehyde as agent causing epigenetic modifications in hematological neoplastic diseases" (Q3142327)

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9 October 2024

  • curprev 22:4522:45, 9 October 2024DG Regio talk contribs 62,813 bytes +27 Set a claim value: summary (P836): O objetivo do projeto é estudar como o formaldeído pode causar alterações no padrão de metilação das citosinas do ADN que causam disfunção hematopoiética, causando o desenvolvimento da síndrome mielodisplásica (SMD) ou leucemia mieloide aguda (LMA). Para fazer isso, mediremos os níveis de metilo e hidroximetilcitosina em linhas celulares humanas transformadas expostas ao formaldeído e em modelos murinos geneticamente modificados no ADH5 que acumulam...

22 March 2024

20 December 2023

12 June 2023

10 June 2023

4 August 2022

  • curprev 07:0907:09, 4 August 2022DG Regio talk contribs 61,515 bytes +41,185 Changed label, description and/or aliases in et, lt, hr, el, sk, fi, pl, hu, cs, lv, ga, sl, bg, mt, pt, da, ro, sv, nl, fr, de, it, es, and other parts: Adding translations: et, lt, hr, el, sk, fi, pl, hu, cs, lv, ga, sl, bg, mt, pt, da, ro, sv,

16 January 2022

17 December 2021

9 December 2021

2 December 2021

  • curprev 12:4412:44, 2 December 2021DG Regio talk contribs 13,951 bytes +2,116 Created claim: summary (P836): L’objectif de ce projet est d’étudier comment le formaldéhyde peut provoquer des altérations du schéma de méthylation des cytosines d’ADN qui provoquent un dysfonctionnement hématopoïétique, provoquant le développement du syndrome myélodysplasique (SMD) ou de la leucémie myéloïde aiguë (LAM). Pour ce faire, nous allons mesurer les niveaux de méthyl et d’hydroxyméthyl cytosine dans les lignées cellulaires humaines transformées exposées au formald...
  • curprev 12:4412:44, 2 December 2021DG Regio talk contribs 11,835 bytes +179 Changed label, description and/or aliases in fr: translated_label

12 October 2021

  • curprev 13:3913:39, 12 October 2021DG Regio talk contribs 11,656 bytes +150 Changed label, description and/or aliases in en: translated_label
  • curprev 13:3913:39, 12 October 2021DG Regio talk contribs 11,506 bytes +1,837 Created claim: summary (P836): The aim of the project is to study how formaldehyde can cause alterations in the methylation pattern of DNA cytosins that cause haematopoietic dysfunction, causing the development of myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). To do this, we will measure the levels of methyl and hydroxymethyl cytosine in transformed human cell lines exposed to formaldehyde and in genetically modified murine models in ADH5 that naturally accum...

10 October 2021

9 October 2021

7 October 2021