STUDY OF METHODS FOR CONVERTING RAMOPLANINA INTO THE NAI-603 SEMI-SYNTHETIC DERIVATIVE (Q2044180)

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Project Q2044180 in Italy
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English
STUDY OF METHODS FOR CONVERTING RAMOPLANINA INTO THE NAI-603 SEMI-SYNTHETIC DERIVATIVE
Project Q2044180 in Italy

    Statements

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    12,500.0 Euro
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    25,000.0 Euro
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    50.0 percent
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    30 January 2018
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    29 September 2018
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    30 December 2018
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    NAICONS S.R.L.
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    45°28'0.48"N, 9°11'25.80"E
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    LA RAMOPLANINA E UN ANTIBIOTICO DI ORIGINE NATURALE CON ATTIVITA MOLTO POTENTE NEI CONFRONTI DI PATOGENI GRAM-POSITIVI MULTI-RESISTENTI. TUTTAVIA, LA RAMOPLANINA NON E UTILIZZABILE COME FARMACO SISTEMICO PER IL TRATTAMENTO DI GRAVI INFEZIONI OSPEDALIERE, IN QUANTO NON E LOCALMENTE TOLLERATA. TUTTAVIA, E STATO POSSIBILE OTTENERE UN DERIVATO SEMI-SINTETICO, DENOMINATO NAI-603, CHE POSSIEDE LE STESSE CARATTERISTICHE ANTIBATTERICHE E FARMACOLOGICHE DI RAMOPLANINA (SPETTRO ANTIBATTERICO, ATTIVI (Italian)
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    RAMOPLANINA AND AN ANTIBIOTIC OF NATURAL ORIGIN WITH HIGHLY POTENT ACTIVITIES WITH REGARD TO POSITIVE GRAM-POSITIVE PATHOGENS MULTI-RESISTING. HOWEVER, RAMOPLANINA CANNOT BE USED AS A SYSTEMIC DRUG FOR TREATMENT OF SERIOUS HOSPITAL INFECTIONS, AS IT IS NOT AND LOCALLY TOLERATED. HOWEVER, AND IT IS POSSIBLE TO OBTAIN A SEMI-SYNTHETIC DERIVATIVE, KNOWN AS NAI-603, WHICH HAS THE SAME ANTIBACTERIAL AND PHARMACOLOGICAL CHARACTERISTICS AS RAMOPLANINA (ANTI-BACTERIAL SPECTRUM, ASSETS (English)
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    Identifiers

    E47H18000630007
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