New platic complexes for anticancer therapy (Q10095)

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Revision as of 14:54, 22 October 2020 by DG Regio (talk | contribs) (‎Removed claim: summary (P836): The project is subject to new currency, complex, with increased reactivity in an internal environment marked by the presence of weakly bound, potentially reactive anon-ligands of strong conjugated acids. The solution will result in a completely new group of Pt (IV) of treatments for cancer therapies with increased toxicity and selective treatment for cancer cells, little toxicity to healthy cells, and high bioavailability from GIT, allowing o...)
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Project in Czech Republic financed by DG Regio
Language Label Description Also known as
English
New platic complexes for anticancer therapy
Project in Czech Republic financed by DG Regio

    Statements

    country
    Czechia
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    EU contribution
    5,848,500.0 Czech koruna
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    233,940.0 Euro
    exchange rate to Euro
    0.04 Euro
    point in time
    10 January 2020
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    budget
    15,596,000.0 Czech koruna
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    623,840.0 Euro
    exchange rate to Euro
    0.04 Euro
    point in time
    10 January 2020
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    co-financing rate
    37.5 percent
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    start time
    15 June 2016
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    expected end time
    28 September 2019
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    beneficiary name (string)
    VUAB Pharma a.s.
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    beneficiary
    VUAB Pharma
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    coordinate location

    50°9'46.91"N, 14°23'2.26"E
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    postal code
    25263
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    summary
    Předmětem řešení projektu jsou nové platičité komplexy (Pt(IV)komplexy) se zvýšenou reaktivitou ve vnitrobuněčném prostředí vyznačené tím, že obsahují slabě vázané a potenciálně reaktivní ekvatoriální anion-ligandy bází silných konjugovaných kyselin. Výsledkem řešení bude zcela nová skupina Pt(IV)komplexů pro protinádorovou terapii se zvýšenou toxicitou a selektivitou na nádorové buňky, s malou toxicitou na zdravé buňky a s dobrou biologickou dostupností z GIT, umožňující perorální podání. a. (Czech)
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    Identifiers

    Czech Kohesio ID
    CZ.01.1.02/0.0/0.0/15_018/0004605
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