PRE-CLINICAL DEVELOPMENT OF AN IP3K INHIBITOR FOR SOLID CANCER TREATMENT (Q2035314)

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Project Q2035314 in Italy
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English
PRE-CLINICAL DEVELOPMENT OF AN IP3K INHIBITOR FOR SOLID CANCER TREATMENT
Project Q2035314 in Italy

    Statements

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    500,629.91 Euro
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    1,002,016.42 Euro
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    49.96 percent
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    13 December 2016
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    6 July 2019
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    CNR - CONSIGLIO NAZIONALE DELLE RICERCHE
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    MENARINI RICERCHE S.P.A.
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    41°40'3.11"N, 12°30'17.24"E
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    IL PROGETTO SI PROPONE LA CARATTERIZZAZIONE PRECLINICA DEL MEN1611, UN NUOVO INIBITORE DI PI3K CHE HA LA CAPACITà DI INIBIRE IN MODO PREFERENZIALE L?ISOFORMA ALFA, WILD TYPE E MUTATA. VERRANNO STUDIATI I DETERMINANTI MOLECOLARI DELLA SENSIBILITà (Italian)
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    THE PROJECT IS PROPOSED FOR THE PRE-CLINICAL CHARACTERISATION OF THE MEN1611, A NEW P3K INHIBITOR WHICH HAS THE CAPACITY TO BLOCK, IN A PREFERENTIAL MANNER, THE ALPHA, WILD, AND THE RANGE WHICH HAVE CHANGED. THE MOLECULAR DETERMINANTS OF AWARENESS WILL BE STUDIED. (English)
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    LE PROJET PROPOSE LA CARACTÉRISATION PRÉCLINIQUE DU MEN1611, UN NOUVEL INHIBITEUR PI3K CAPABLE D’INHIBER PRÉFÉRENTIELLEMENT L’ISOFORME ALPHA, DE TYPE SAUVAGE ET MUTÉ. LES DÉTERMINANTS MOLÉCULAIRES DE LA SENSIBILITÉ SERONT ÉTUDIÉS (French)
    16 December 2021
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    HET PROJECT STELT DE PREKLINISCHE KARAKTERISERING VAN DE MEN1611 VOOR, EEN NIEUWE PI3K-REMMER DIE DE MOGELIJKHEID HEEFT OM BIJ VOORKEUR HET ALFA-ISOFORM, WILDTYPE EN GEMUTEERD TE REMMEN. MOLECULAIRE DETERMINANTEN VAN GEVOELIGHEID ZULLEN WORDEN ONDERZOCHT (Dutch)
    23 December 2021
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    DAS PROJEKT SCHLÄGT DIE PRÄKLINISCHE CHARAKTERISIERUNG DES MEN1611 VOR, EINEM NEUEN PI3K-INHIBITOR, DER DIE FÄHIGKEIT HAT, DIE ALPHA-ISOFORM, WILDE ART UND MUTATION BEVORZUGT ZU HEMMEN. MOLEKULARE DETERMINANTEN DER SENSITIVITÄT WERDEN UNTERSUCHT (German)
    24 December 2021
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    EL PROYECTO PROPONE LA CARACTERIZACIÓN PRECLÍNICA DEL MEN1611, UN NUEVO INHIBIDOR PI3K QUE TIENE LA CAPACIDAD DE INHIBIR PREFERENTEMENTE LA ISOFORMA ALFA, SALVAJE Y MUTADA. SE ESTUDIARÁN LOS DETERMINANTES MOLECULARES DE LA SENSIBILIDAD (Spanish)
    25 January 2022
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    POMEZIA
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    Identifiers

    F57H18000070007
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