TECHNOLOGIES FOR FULLY AUTOMATED WORKFLOWS IN INFECTIOUS MOLECULAR DIAGNOSTICS IN REAL TIME PCR (Q4242506)

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Project Q4242506 in Italy
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English
TECHNOLOGIES FOR FULLY AUTOMATED WORKFLOWS IN INFECTIOUS MOLECULAR DIAGNOSTICS IN REAL TIME PCR
Project Q4242506 in Italy

    Statements

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    88,609.95 Euro
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    177,219.9 Euro
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    50.0 percent
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    DOTT. DINO PALADIN
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    LA METODICA ANALITICA REAL TIME PCR E' ORMAI AMPIAMENTE UTILIZZATA IN DIAGNOSTICA MOLECOLARE PER L - IDENTIFICAZIONE E LA QUANTIFICAZIONE DI SEQUENZE DI ACIDI NUCLEICI (DNA O RNA). TRA LE VARIE APPLICAZIONI, SI BASANO IN PARTICOLARE SU DI ESSA NUMEROSI DISPOSITIVI MEDICO-DIAGNOSTICI IN VITRO (IVD, IN VITRO DIAGNOSTICS) PER LA DETERMINAZIONE E LA QUANTIFICAZIONE DI VIRUS TRAMITE IL RICONOSCIMENTO E LA QUANTIFICAZIONE DI SEQUENZE DI ACIDI NUCLEICI CARATTERISTICHE DI CIASCUN MICRORGANISMO PATOGENO. LA CRESCENTE DIFFUSIONE DI QUESTE METODICHE SI E' ACCOMPAGNATA ALLA NECESSITA' DI UNA SEMPRE MAGGIORE AUTOMAZIONE PER SOSTENERE I MAGGIORI CARICHI DI ANALISI RICHIESTI, RIDURRE LA PROBABILITA' DI ERRORE UMANO E GARANTIRE TRACCIABILITA' AL PROCESSO. IN QUESTO PROGETTO VERRANNO SVILUPPATE TECNOLOGIE UTILIZZABILI PER L - AUTOMAZIONE DI QUEI PASSAGGI DEL FLUSSO DI LAVORO CHE ALLO STATO DELL - ARTE ATTUALE SONO ANCORA TIPICAMENTE EFFETTUATI MANUALMENTE: CARICAMENTO DELLO STRUMENTO ANALITICO (TE (Italian)
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    REAL TIME PCR ANALYTICAL METHOD IS NOW WIDELY USED IN MOLECULAR DIAGNOSTICS FOR THE IDENTIFICATION AND QUANTIFICATION OF NUCLEIC ACID SEQUENCES (DNA OR RNA). AMONG THE VARIOUS APPLICATIONS, MANY IN VITRO DIAGNOSTIC MEDICAL DEVICES (IVDS) FOR THE DETERMINATION AND QUANTIFICATION OF VIRUSES BY RECOGNITION AND QUANTIFICATION OF NUCLEIC ACID SEQUENCES CHARACTERISTIC OF EACH PATHOGENIC MICRO-ORGANISM ARE BASED ON IT. THE INCREASING SPREAD OF THESE METHODS HAS BEEN ACCOMPANIED BY THE NEED FOR INCREASING AUTOMATION TO SUPPORT THE INCREASED LOADS OF ANALYSIS REQUIRED, REDUCE THE LIKELIHOOD OF HUMAN ERROR AND ENSURE TRACEABILITY IN THE PROCESS. IN THIS PROJECT WILL BE DEVELOPED TECHNOLOGIES USABLE FOR THE AUTOMATION OF THOSE STEPS OF THE WORKFLOW THAT IN THE STATE OF THE CURRENT ART ARE STILL TYPICALLY CARRIED OUT MANUALLY: LOADING OF THE ANALYTICAL TOOL (YOU (English)
    2 February 2022
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    LA MÉTHODE D’ANALYSE PCR EN TEMPS RÉEL EST MAINTENANT LARGEMENT UTILISÉE DANS LES DIAGNOSTICS MOLÉCULAIRES POUR L’IDENTIFICATION ET LA QUANTIFICATION DES SÉQUENCES D’ACIDES NUCLÉIQUES (ADN OU ARN). PARMI LES DIVERSES APPLICATIONS, DE NOMBREUX DISPOSITIFS MÉDICAUX DE DIAGNOSTIC IN VITRO (DIV) POUR LA DÉTERMINATION ET LA QUANTIFICATION DES VIRUS PAR LA RECONNAISSANCE ET LA QUANTIFICATION DES SÉQUENCES D’ACIDES NUCLÉIQUES CARACTÉRISTIQUES DE CHAQUE MICRO-ORGANISME PATHOGÈNE SONT BASÉS SUR CELUI-CI. LA PROPAGATION CROISSANTE DE CES MÉTHODES S’EST ACCOMPAGNÉE DE LA NÉCESSITÉ D’ACCROÎTRE L’AUTOMATISATION AFIN DE SOUTENIR L’AUGMENTATION DES CHARGES D’ANALYSE NÉCESSAIRES, DE RÉDUIRE LA PROBABILITÉ D’ERREUR HUMAINE ET D’ASSURER LA TRAÇABILITÉ DU PROCESSUS. DANS CE PROJET SERONT DÉVELOPPÉS DES TECHNOLOGIES UTILISABLES POUR L’AUTOMATISATION DES ÉTAPES DU FLUX DE TRAVAIL QUI, DANS L’ÉTAT DE L’ART ACTUEL SONT ENCORE GÉNÉRALEMENT EFFECTUÉS MANUELLEMENT: CHARGEMENT DE L’OUTIL D’ANALYSE (VOUS (French)
    2 February 2022
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    PADOVA
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