The use of spectroscopic methods to evaluate bone formation on biomaterials of ceramic type in vitro (Q84310)
Jump to navigation
Jump to search
Project Q84310 in Poland
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | The use of spectroscopic methods to evaluate bone formation on biomaterials of ceramic type in vitro |
Project Q84310 in Poland |
Statements
801,380.0 zloty
0 references
801,380.0 zloty
0 references
100.0 percent
0 references
1 July 2018
0 references
30 June 2020
0 references
UNIWERSYTET MEDYCZNY W LUBLINIE
0 references
The increasing number of accidents, injuries and bone tumours along with developments in medical sciences result in growing demand for bone substitute materials. The global bone graftsand substitutes (BGS) market is expected to reach US$3482.0 million by 2023 according to a new report published by Transparency Market Research. Nowadays the challenge for the Medical engineering technologies is designing bone substitute materials without the providing animal test. In this proposed project the modern advanced spectroscopic methods FT-IR, Raman, Solid state NMR and LC MS/MS will be used to access bone formation markers produced by stem cells cultured directly on the ceramic-based biomaterial. This approach allows to detect structural changes of the organic and inorganic phase of designed biomaterials in vitro. These experiments will assess the bioactivity of the modified biomaterial without the need for performing animal testing. (Polish)
0 references
The increasing number of accidents, injuries and bone tumours along with developments in medical sciences result in growing demand for bone substitute materials. The global bone graftsand Substitutes (BGS) market is expected to reach US$3482.0 million by 2023 according to a new report published by Transparency Market Research. Nowadays the challenge for the Medical engineering technologies is designing bone substitute materials without the providing animal test. In this proposed project the modern advanced spectroscopic methods FT-IR, Raman, Solid state NMR and LC MS/MS will be used to access bone formation markers produced by stem cells cultured directly on the ceramic-based biomaterial. This approach allows to detect structural changes of the organic and inorganic phase of designed biomaterials in vitro. These experiments will assess the bioactivity of the modified biomaterial without the need for performing animal testing. (English)
14 October 2020
0 references
Le nombre croissant d’accidents, de blessures et de tumeurs osseuses ainsi que l’évolution des sciences médicales entraînent une demande croissante de substituts osseux. Selon un nouveau rapport publié par Transparency Market Research, le marché mondial des greffes et des substituts osseux (BGS) devrait atteindre 3482,0 millions de dollars américains d’ici 2023. Aujourd’hui, le défi pour les technologies d’ingénierie médicale est de concevoir des matériaux de remplacement osseux sans l’expérimentation animale. Dans ce projet proposé, les méthodes spectroscopiques avancées modernes FT-IR, Raman, Solid State NMR et LC MS/MS seront utilisées pour accéder aux marqueurs de formation osseuse produits par des cellules souches cultivées directement sur le biomatériau céramique. Cette approche permet de détecter les changements structurels de la phase organique et inorganique des biomatériaux conçus in vitro. Ces expériences permettront d’évaluer la bioactivité du biomatériau modifié sans qu’il soit nécessaire d’effectuer des essais sur les animaux. (French)
30 November 2021
0 references
Identifiers
POIR.04.04.00-00-4398/17
0 references