Methods of non-stationary signal processing for more sensitive NMR spectroscopy (Q84303)
Jump to navigation
Jump to search
Project Q84303 in Poland
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | Methods of non-stationary signal processing for more sensitive NMR spectroscopy |
Project Q84303 in Poland |
Statements
1,929,569.0 zloty
0 references
1,929,569.0 zloty
0 references
100.0 percent
0 references
1 July 2018
0 references
30 June 2021
0 references
UNIWERSYTET WARSZAWSKI
0 references
Nuclear magnetic resonance (NMR) spectroscopy is one of the most powerful tools of chemical analysis. Invention of multidimensional NMR in 1970s opened way to such advanced studies as determination of biomolecular structures in solution. However, multidimensional spectroscopy is very time-consuming due to rules of conventional signal sampling theory. The measurement times can reach several days to provide sufficient resolution. Moreover, many NMR experiments have to be repeated in varying conditions which makes them prohibitively long. The current project proposes a new approach to accelerate the serial NMR measurements manyfold. The approach, based on Radon transform and fractional Fourier transform will be developed and implemented in various kinds of NMR spectroscopy: solid state, pure-shift, time-resolved and diffusion-ordered. Results will contribute to more efficient exploitation of NMR in pharmaceutical research and food industry, to mention just few applications. (Polish)
0 references
Nuclear magnetic resonance (NMR) spectroscopy is one of the most powerful tools of chemical analysis. Invention of multidimensional NMR in 1970s opened way to such advanced studies as determination of biomolecular structures in solution. However, multidimensional spectroscopy is very time-consuming due to rules of conventional signal sampling theory. The measurement times can reach several days to provide sufficient resolution. Moreover, many NMR experiments have to be repeated in varying conditions which makes them prohibitively long. The current project Proposes a new approach to accelerate the series NMR measurements manyfold. The approach, based on Radon transform and fractional Fourier transform will be developed and implemented in various kinds of NMR spectroscopy: solid state, pure-shift, time-resolved and diffusion-ordered. Results will contribute to more efficient exploitation of NMR in pharmaceutical research and food industry, to mention just few applications. (English)
14 October 2020
0 references
La spectroscopie par résonance magnétique nucléaire (RMN) est l’un des outils les plus puissants d’analyse chimique. L’invention de la RMN multidimensionnelle dans les années 1970 a ouvert la voie à des études aussi avancées que la détermination des structures biomoléculaires en solution. Cependant, la spectroscopie multidimensionnelle prend beaucoup de temps en raison des règles de la théorie conventionnelle de l’échantillonnage des signaux. Les temps de mesure peuvent atteindre plusieurs jours pour fournir une résolution suffisante. De plus, de nombreuses expériences de RMN doivent être répétées dans des conditions variables, ce qui les rend prohibitivement longues. Le projet actuel propose une nouvelle approche pour accélérer de nombreuses fois les mesures de la RMN en série. L’approche basée sur la transformation du radon et la transformation fractionnelle de Fourier sera développée et mise en œuvre dans divers types de spectroscopie RMN: à l’état solide, au changement pur, à la résolution dans le temps et à l’ordre de diffusion. Les résultats contribueront à une exploitation plus efficace de la RMN dans la recherche pharmaceutique et l’industrie alimentaire, pour ne citer que quelques applications. (French)
30 November 2021
0 references
Identifiers
POIR.04.04.00-00-4343/17
0 references