No label defined (Q3157157)

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Revision as of 15:19, 12 October 2021 by DG Regio (talk | contribs) (‎Created claim: summary (P836): VASCULAR DISEASES KNOWN AS WILT ARE AMONG THE MOST DESTRUCTIVE ON ANNUAL CROPS AND WOODY PLANTS, AFFECTING FOOD AND FEED PRODUCTION AND NATURAL ECOSYSTEMS. RALSTONIA SOLANACEARUM IS A SOIL-BORNE BACTERIA THAT IS AN EXCELLENT MODEL FOR STUDYING VASCULAR PATHOGENS, AS WE HAVE SHOWN IN OUR PREVIOUS WORK. OUR HYPOTHESIS IS THAT A BETTER KNOWLEDGE OF THE ARCHITECTURE OF THE VESSELS, THE GENIC EXPRESSION IN R. SOLANACEARUM AND THE VIRULENCE INHIBITORS...)
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Project Q3157157 in Spain
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Project Q3157157 in Spain

    Statements

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    127,050.0 Euro
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    254,100.0 Euro
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    50.0 percent
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    30 December 2016
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    31 December 2020
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    CENTRO DE INVESTIGACION EN AGRIGENOMICA
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    41°29'27.71"N, 2°8'15.00"E
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    08266
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    LAS ENFERMEDADES VASCULARES CONOCIDAS COMO MARCHITEZ SE ENCUENTRAN ENTRE LAS MAS DESTRUCTIVAS SOBRE CULTIVOS ANUALES Y PLANTAS LEÑOSAS, AFECTANDO A LA PRODUCCION DE ALIMENTOS Y PIENSOS Y A LOS ECOSISTEMAS NATURALES. RALSTONIA SOLANACEARUM ES UNA BACTERIA TRANSMITIDA POR EL SUELO QUE CONSTITUYE UN EXCELENTE MODELO PARA ESTUDIAR PATOGENOS VASCULARES, COMO HEMOS DEMOSTRADO EN NUESTRO TRABAJO ANTERIOR. NUESTRA HIPOTESIS ES QUE UN MEJOR CONOCIMIENTO DE LA ARQUITECTURA DE LOS VASOS, DE LA EXPRESION GENICA EN R. SOLANACEARUM Y DE LOS INHIBIDORES DE LA VIRULENCIA PROPORCIONARA NUEVAS ESTRATEGIAS CONTRA LAS ENFERMEDADES BACTERIANAS Y VASCULARES DE LAS PLANTAS QUE PODRA SER APLICADA PARA EL TRATAMIENTO DE LAS PRINCIPALES AMENAZAS AGRICOLAS. ESTE PROYECTO PRETENDE: 1) IDENTIFICAR GENES ESENCIALES PARA LA VIRULENCIA DE R. SOLANACEARUM, MEDIANTE LA REALIZACION DE UN ANALISIS EXHAUSTIVO DE TRANSCRIPTOMICA LAS DIFERENTES ETAPAS DEL CICLO DE VIDA DE LA BACTERIA Y EL DESARROLLO DE NUEVAS TECNOLOGIAS PARA EL SEGUIMIENTO DEL PATOGENO Y LA SECRECION DE EFECTORES IN PLANTA; 2) ESTUDIAR SISTEMATICAMENTE LOS DIFERENTES NIVELES DE DEFENSA DESARROLLADAS POR LAS PLANTAS PARA CONTRARRESTAR LA INFECCION POR R. SOLANACEARUM, MEDIANTE LA DISECCION DE LOS MECANISMOS VEGETALES QUE GENERAN BARRERAS ESTRUCTURALES VASCULARES, LA CARACTERIZACION GENETICA DE LAS PRIMERAS DEFENSAS INDUCIBLES ESPECIFICAS DE LA RAIZ, LA IDENTIFICACION DE PROTEASAS DE AOPLASTO Y XILEMA QUE PARTICIPAN EN LA LUCHA CONTRA EL PATOGENO Y LA EVALUACION DEL PAPEL DE LOS AGREGADOS PRETEICOS EN EL CONTEXTO DE LA MUERTE CELULAR INDUCIDA POR PATOGENOS; Y 3) IDENTIFICAR NUEVOS PRODUCTOS NATURALES EFICACES CONTRA LAS ENFERMEDADES BACTERIANAS DE LAS PLANTAS EN COLABORACION CON EMPRESAS DE AGROBIOTECNOLOGIA Y EXPERTOS DE NANOMATERIALES. A LARGO PLAZO, ESPERAMOS QUE ESTE PROYECTO CONTRIBUYA A AUMENTAR LA PRODUCCION DE ALIMENTOS DE MANERA SOSTENIBLE, LUCHANDO DE FORMA DURADERA CONTRA LA ENFERMEDAD. EL PROYECTO ESTA RESPALDADO POR UNA PYME ESPAÑOLA, DOS COMPAÑIAS MULTINACIONALES Y EL INSTITUTO NACIONAL DE INVESTIGACION AGRICOLA DEL URUGUAY, CON QUIENES COLABORAMOS. ESTO ASEGURARA LA TRANSFERENCIA DE LOS RESULTADOS Y METODOLOGIAS HACIA EL SISTEMA PRODUCTIVO Y, POR TANTO, A LA SOCIEDAD EN GENERAL. (Spanish)
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    VASCULAR DISEASES KNOWN AS WILT ARE AMONG THE MOST DESTRUCTIVE ON ANNUAL CROPS AND WOODY PLANTS, AFFECTING FOOD AND FEED PRODUCTION AND NATURAL ECOSYSTEMS. RALSTONIA SOLANACEARUM IS A SOIL-BORNE BACTERIA THAT IS AN EXCELLENT MODEL FOR STUDYING VASCULAR PATHOGENS, AS WE HAVE SHOWN IN OUR PREVIOUS WORK. OUR HYPOTHESIS IS THAT A BETTER KNOWLEDGE OF THE ARCHITECTURE OF THE VESSELS, THE GENIC EXPRESSION IN R. SOLANACEARUM AND THE VIRULENCE INHIBITORS WILL PROVIDE NEW STRATEGIES AGAINST BACTERIAL AND VASCULAR DISEASES OF PLANTS THAT CAN BE APPLIED TO THE TREATMENT OF THE MAIN AGRICULTURAL THREATS. THIS PROJECT AIMS TO: 1) IDENTIFY GENES ESSENTIAL FOR THE VIRULENCE OF R. SOLANACEARUM, BY PERFORMING A THOROUGH ANALYSIS OF TRANSCRIPTOMICA THE DIFFERENT STAGES OF THE LIFE CYCLE OF THE BACTERIA AND THE DEVELOPMENT OF NEW TECHNOLOGIES FOR THE MONITORING OF PATHOGENS AND SECRETION OF EFFECTORS IN PLANT; 2) SYSTEMATICALLY STUDY THE DIFFERENT LEVELS OF DEFENSE DEVELOPED BY PLANTS TO COUNTERACT THE INFECTION BY R. SOLANACEARUM, THROUGH THE DISSECTION OF THE PLANT MECHANISMS THAT GENERATE VASCULAR STRUCTURAL BARRIERS, GENETIC CHARACTERISATION OF THE FIRST INDUCIBLE DEFENSES SPECIFIC TO THE ROOT, THE IDENTIFICATION OF AOPLASTE PROTEASES AND XYLEMA INVOLVED IN THE FIGHT AGAINST PATHOGENS AND THE EVALUATION OF THE ROLE OF PRETEICOS AGGREGATES IN THE CONTEXT OF PATHOGEN-INDUCED CELL DEATH; AND 3) IDENTIFY NEW EFFECTIVE NATURAL PRODUCTS AGAINST BACTERIAL PLANT DISEASES IN COLLABORATION WITH AGROBIOTECNOLOGY COMPANIES AND NANOMATERIAL EXPERTS. IN THE LONG TERM, WE HOPE THAT THIS PROJECT WILL CONTRIBUTE TO INCREASING FOOD PRODUCTION IN A SUSTAINABLE WAY, FIGHTING THE DISEASE IN A LASTING WAY. THE PROJECT IS SUPPORTED BY A SPANISH SME, TWO MULTINATIONAL COMPANIES AND THE NATIONAL AGRICULTURAL RESEARCH INSTITUTE OF URUGUAY, WITH WHOM WE COLLABORATE. THIS WILL ENSURE THE TRANSFER OF RESULTS AND METHODS TO THE PRODUCTIVE SYSTEM AND, THEREFORE, TO SOCIETY IN GENERAL. (English)
    12 October 2021
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    Cerdanyola del Vallès
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    Identifiers

    AGL2016-78002-R
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