No label defined (Q3250163)
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Project Q3250163 in Spain
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | No label defined |
Project Q3250163 in Spain |
Statements
5,000.0 Euro
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10,000.0 Euro
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50.0 percent
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1 January 2019
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31 December 2019
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PROTOQSAR 2000 SL
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46190
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PANACHE GENERARÁ PÉPTIDOS MODIFICADOS Y PEPTIDOMIMÉTICOS DIRIGIDOS CONTRA PANX1, CX43 Y CX32, UTILIZANDO MOLDES CONFORMACIONALES SIN PRECEDENTES PARA ENTREGAR COMPUESTOS DE PLOMO SELECTIVOS HACIA INHIBIDORES DE HEMICANAL TERAPÉUTICAMENTE PROMETEDORES. COMO PRUEBA DE CONCEPTO, SE ANALIZARÁN LOS ANÁLOGOS DE PÉPTIDOS GENERADOS A PARTIR DE RESTOS DE PANX1, CX43 Y CX32 PARA DETERMINAR SU POTENCIAL PARA ALIVIAR CARACTERÍSTICAS PATOLÓGICAS EN MODELOS ANIMALES DE ENFERMEDADES INFLAMATORIAS EN EL SISTEMA CARDIOVASCULAR, EL HÍGADO Y LAS ARTICULACIONES. (Spanish)
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PANACHE GENERATE MODIFIED PEPTIDES AND PEPTIDOMIMETICS DIRECTED AGAINST PANX1, CX43 AND CX32, USING CONFORMATIONAL MOLDS TO DELIVER UNPRECEDENTED LEAD COMPOUNDS SELECTIVE INHIBITORS TOWARDS HEMICHANNEL THERAPEUTICALLY PROMISING. AS PROOF OF CONCEPT, PEPTIDE ANALOGS ARE ANALYZED GENERATED FROM RESIDUES PANX1, CX43 AND CX32 TO DETERMINE ITS POTENTIAL TO ALLEVIATE PATHOLOGICAL FEATURES IN ANIMAL MODELS OF INFLAMMATORY DISEASES IN THE CARDIOVASCULAR SYSTEM, LIVER AND JOINTS. (English)
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Paterna
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Identifiers
20F01020101U_IVCI00000APEA9011
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