Cross-border network of personalised immunotherapies in the treatment of non-Hodgkin's lymphoma (Q4295764)

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Cross-border network of personalised immunotherapies in the treatment of non-Hodgkin's lymphoma
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    1,343,659.2 Euro
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    2,067,168.0 Euro
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    65.0 percent
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    1 January 2018
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    31 December 2020
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    Consorci Institut d'Investigacions Biomèdiques August Pi i Sunyer
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    43°33'45.04"N, 1°25'34.57"E
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    41°58'13.30"N, 2°47'47.26"E
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    41°23'25.08"N, 2°9'12.46"E
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    42°45'15.95"N, 1°38'14.10"W
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    43°36'43.99"N, 1°23'51.29"E
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    In the era of personalised medicine, IMLINFO aims to create a repository of Non-Hodgkin Lymphoma (NHL) associated to a 3 dimension (3D) culture platform, that will allow the determination of efficacy of new immunotherapy treatments. 450-1050 new NHL cases are detected each year inside POCTEFA´s territory ; current treatments include a polychemotherapy backbone of variable efficacy often associated to significant side effects. IMLINFO gathers hospitals, research institutes, one pharmaceutical company and one technological company, to establish personalized immunotherapies that reactivate patient´s immune system, inducing tumor regression in the absence of chemotherapy. IMLINFO is a multidisciplinary team with experts in 3D culture and multicellular cultures, together with the characterisation of 3D structures and drug penetrance by next generation microscopy. Moreover, the pharmaceutical company integrated in IMLINFO has recognized experience in the development of small molecules as innovative immunotherapies, some of them already licensed to international pharmaceutical companies. Aiming to progress towards personalized medicine, the cross-border cooperation is mandatory for the collection of material of a significant number of NHL patients from each of the hospital in the cross-border territory, together with scientific and technological collaboration. (English)
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