Patenting of the invention “Construction, Properties and Purification Techniques for Heterodimeric Mixed GCSF and SCF Protein” (Q3786805)

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Project Q3786805 in Lithuania
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English
Patenting of the invention “Construction, Properties and Purification Techniques for Heterodimeric Mixed GCSF and SCF Protein”
Project Q3786805 in Lithuania

    Statements

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    12,045.0 Euro
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    16,060.0 Euro
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    75.0 percent
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    27 September 2017
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    1 April 2018
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    Uždaroji akcinė bendrovė "Profarma"
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    54°37'34.50"N, 25°8'26.59"E
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    LT-02241
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    Patentinė paraiška atskleidžia sulietų biofarmacinių baltymų biologines savybes ir jų paruošimo metodus. Baltymai sukonstruoti iš granulocitų kolonijas stimuliuojančio faktoriaus ir kamieninių ląstelių faktoriaus. Išradimo duomenys parodo, kad šios baltymo konstrukcijos gali būti panaudotos terapijoje, kadangi yra nustatytas jų sinergetinis veikimas in vivo (pelėse), o taip pat pademonstruotas prailgintas cirkuliacijos puslaikis palyginus su kiekvienu preparato konstrukciją sudarančiu monomeriniu baltymu. (Lithuanian)
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    The patent application reveals the biological properties of the fusion of biopharmaceutical proteins and the methods of their preparation. Proteins are constructed from granulocyte colony stimulating factor and stem cell factor. The data from the invention indicate that these protein designs can be used for therapeutic use, since their synergistic activity in vivo (mouse) has been established, as well as an extended half-life of circulation compared to each monomeric protein in the formulation. (English)
    1 February 2022
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    V.A. Graičiūno 6, Vilnius
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    Identifiers

    01.2.1-MITA-T-845-01-0006
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