The use of spectroscopic methods to evaluate bone formation on biomaterials of ceramic type in vitro (Q84310)

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Project Q84310 in Poland
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English
The use of spectroscopic methods to evaluate bone formation on biomaterials of ceramic type in vitro
Project Q84310 in Poland

    Statements

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    801,380.0 zloty
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    192,331.20 Euro
    13 January 2020
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    801,380.0 zloty
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    192,331.20 Euro
    13 January 2020
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    100.0 percent
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    1 July 2018
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    30 June 2020
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    UNIWERSYTET MEDYCZNY W LUBLINIE
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    The increasing number of accidents, injuries and bone tumours along with developments in medical sciences result in growing demand for bone substitute materials. The global bone graftsand substitutes (BGS) market is expected to reach US$3482.0 million by 2023 according to a new report published by Transparency Market Research. Nowadays the challenge for the Medical engineering technologies is designing bone substitute materials without the providing animal test. In this proposed project the modern advanced spectroscopic methods FT-IR, Raman, Solid state NMR and LC MS/MS will be used to access bone formation markers produced by stem cells cultured directly on the ceramic-based biomaterial. This approach allows to detect structural changes of the organic and inorganic phase of designed biomaterials in vitro. These experiments will assess the bioactivity of the modified biomaterial without the need for performing animal testing. (Polish)
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    The increasing number of accidents, injuries and bone tumours along with developments in medical sciences result in growing demand for bone substitute materials. The global bone graftsand Substitutes (BGS) market is expected to reach US$3482.0 million by 2023 according to a new report published by Transparency Market Research. Nowadays the challenge for the Medical engineering technologies is designing bone substitute materials without the providing animal test. In this proposed project the modern advanced spectroscopic methods FT-IR, Raman, Solid state NMR and LC MS/MS will be used to access bone formation markers produced by stem cells cultured directly on the ceramic-based biomaterial. This approach allows to detect structural changes of the organic and inorganic phase of designed biomaterials in vitro. These experiments will assess the bioactivity of the modified biomaterial without the need for performing animal testing. (English)
    14 October 2020
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    Identifiers

    POIR.04.04.00-00-4398/17
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