Nanoantibodies based on conexin and panexin as new hemicanal inhibitors for the therapy of inflammatory diseases COPACABANA (Q3252312)
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Project Q3252312 in Spain
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | Nanoantibodies based on conexin and panexin as new hemicanal inhibitors for the therapy of inflammatory diseases COPACABANA |
Project Q3252312 in Spain |
Statements
6,250.0 Euro
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12,500.0 Euro
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50.0 percent
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1 January 2018
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31 December 2018
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PROTOQSAR 2000 SL
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39°28'10.96"N, 0°22'34.82"W
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46250
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El proyecto COPACABANA pretende introducir nano-anticuerpos elegibles para fines terapéuticos dirigidos contra Cx43, Cx32, Cx26 y Panx1, utilizando protocolos novedosos, incluida la inmunización con ADN de llamas combinada con tecnología de nano-discos. COPACABANA probará estos nano-anticuerpos por su potencial para inhibir los hemicanales y para aliviar las características patológicas en modelos en roedores de una variedad de enfermedades inflamatorias. (Spanish)
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The COPACABANA eligible project aims to introduce nano-antibodies for therapeutic purposes directed against Cx43, Cx32, Cx26 and Panx1, using novel protocols including DNA immunization with combined flames nano-discs. COPACABANA test these nano-antibodies for their potential to inhibit hemichannels and to alleviate the pathological features in rodent models of a variety of inflammatory diseases. (English)
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Valencia
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Identifiers
20F01020101U_IVCI00000APEA8025
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