Platform for fast, non-powerful imaging, identification and sorting of subtypes of leukaemia cells (Q84151): Difference between revisions
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(Removed claim: summary (P836): Leukaemia are haematopoietic necrosis produced by genetic aberrations, resulting in biochemical, proteomic and metabolomic changes.The diagnostic base is a complex procedure involving the identification of genetic changes and phenotypic transformation of leukaemia cells.The aim of this project is to create a micro-fluident diagnostic device with a microcopy technology based on SRS micro-replicate (Stimulated Raman Sctering) and then on a clini...) |
(Created claim: summary (P836): Leukaemias are haematopoietic tumours resulting from genetic aberrations that lead to biochemical, proteomic and metabolomic changes. Diagnosis is based on a complex procedure involving the identification of genetic changes and phenotypic leukaemia cells. The aim of this project is to create a microfluidic diagnostic device with SRS-based detection technology (Stimulated Raman Scattering), followed by its clinical implementation. Through the int...) |
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Leukaemias are haematopoietic tumours resulting from genetic aberrations that lead to biochemical, proteomic and metabolomic changes. Diagnosis is based on a complex procedure involving the identification of genetic changes and phenotypic leukaemia cells. The aim of this project is to create a microfluidic diagnostic device with SRS-based detection technology (Stimulated Raman Scattering), followed by its clinical implementation. Through the interaction of multidisciplinary teams, the Consortium will conduct multi-faceted studies of Ramanian leukaemia cell spectra and link them to the biological-clinical features of the disease. The developed diagnostic algorithm combined with a unique device will allow for rapid analysis of leukaemia cells and sorting them without using fluorescent markers. The device should allow rapid, objective and cheaper diagnosis at the stage of diagnosis and during the treatment of the disease. (English) | |||||||||||||||
| Property / summary: Leukaemias are haematopoietic tumours resulting from genetic aberrations that lead to biochemical, proteomic and metabolomic changes. Diagnosis is based on a complex procedure involving the identification of genetic changes and phenotypic leukaemia cells. The aim of this project is to create a microfluidic diagnostic device with SRS-based detection technology (Stimulated Raman Scattering), followed by its clinical implementation. Through the interaction of multidisciplinary teams, the Consortium will conduct multi-faceted studies of Ramanian leukaemia cell spectra and link them to the biological-clinical features of the disease. The developed diagnostic algorithm combined with a unique device will allow for rapid analysis of leukaemia cells and sorting them without using fluorescent markers. The device should allow rapid, objective and cheaper diagnosis at the stage of diagnosis and during the treatment of the disease. (English) / rank | |||||||||||||||
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| Property / summary: Leukaemias are haematopoietic tumours resulting from genetic aberrations that lead to biochemical, proteomic and metabolomic changes. Diagnosis is based on a complex procedure involving the identification of genetic changes and phenotypic leukaemia cells. The aim of this project is to create a microfluidic diagnostic device with SRS-based detection technology (Stimulated Raman Scattering), followed by its clinical implementation. Through the interaction of multidisciplinary teams, the Consortium will conduct multi-faceted studies of Ramanian leukaemia cell spectra and link them to the biological-clinical features of the disease. The developed diagnostic algorithm combined with a unique device will allow for rapid analysis of leukaemia cells and sorting them without using fluorescent markers. The device should allow rapid, objective and cheaper diagnosis at the stage of diagnosis and during the treatment of the disease. (English) / qualifier | |||||||||||||||
point in time: 14 October 2020
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Revision as of 14:35, 14 October 2020
Project in Poland financed by DG Regio
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | Platform for fast, non-powerful imaging, identification and sorting of subtypes of leukaemia cells |
Project in Poland financed by DG Regio |
Statements
26,371,262.5 zloty
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26,371,262.5 zloty
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100.0 percent
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1 October 2019
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30 September 2023
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UNIWERSYTET WARSZAWSKI
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Białaczki są nowotworami układu krwiotwórczego, powstającymi w wyniku aberracji genetycznych, które prowadzą do zmian biochemicznych, proteomicznych i metabolomicznych. Podstawę diagnostyki stanowi złożona procedura obejmująca identyfikację zmian genetycznych i fenotypowych komórek białaczkowych. Celem tego projektu jest stworzenie mikrofluidycznego urządzenia diagnostycznego z technologią detekcją opartą o mikroskopię SRS (Stimulated Raman Scattering), a następnie jego kliniczną implementację. Poprzez współdziałanie wielodyscyplinarnych zespołów, Konsorcjum przeprowadzi wielopłaszczyznowe badania widm ramanowskich komórek białaczkowych i powiąże je z biologiczno-klinicznymi cechami choroby. Wytworzony algorytm diagnostyczny w połączeniu z unikalnym urządzeniem umożliwi szybką analizy komórek białaczkowych i ich sortowanie bez użycia znaczników fluorescencyjnych. Urządzenie powinno pozwolić na szybką, obiektywną i tańszą diagnostykę na etapie rozpoznania i w trakcie leczenia choroby. (Polish)
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Leukaemias are haematopoietic tumours resulting from genetic aberrations that lead to biochemical, proteomic and metabolomic changes. Diagnosis is based on a complex procedure involving the identification of genetic changes and phenotypic leukaemia cells. The aim of this project is to create a microfluidic diagnostic device with SRS-based detection technology (Stimulated Raman Scattering), followed by its clinical implementation. Through the interaction of multidisciplinary teams, the Consortium will conduct multi-faceted studies of Ramanian leukaemia cell spectra and link them to the biological-clinical features of the disease. The developed diagnostic algorithm combined with a unique device will allow for rapid analysis of leukaemia cells and sorting them without using fluorescent markers. The device should allow rapid, objective and cheaper diagnosis at the stage of diagnosis and during the treatment of the disease. (English)
14 October 2020
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Identifiers
POIR.04.04.00-00-16ED/18
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