Increase the diagnostic performance of dynamic imaging on a dynamic contrast in personalised oncology by extraction of new and improved biomarkers (Q78907): Difference between revisions

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(‎Removed claim: summary (P836): A dynamic contract on CT (‘DCE’) using CT and MRI is intensively studied in order to allow for an assessment of cancer and other tissues.It has been demonstrated that biomarkers that have been extracted from dynamic contrast trials correlate with physiological and molecular processes that can be observed in the angiogenesis of cancer.These biomarkers can be used to assess the characteristics and maturity of the cancer by stratifying the risk i...)
Property / summary
A dynamic contract on CT (‘DCE’) using CT and MRI is intensively studied in order to allow for an assessment of cancer and other tissues.It has been demonstrated that biomarkers that have been extracted from dynamic contrast trials correlate with physiological and molecular processes that can be observed in the angiogenesis of cancer.These biomarkers can be used to assess the characteristics and maturity of the cancer by stratifying the risk in patients with cancer.This project will establish an innovative system for a comprehensive DCE analysis.The aim of the project is to increase the effectiveness of diagnostic dynamic imaging by strengthening the contrast in personalised oncology by extraction of new and improved biomarkers.The system will allow interactive collaboration of interdisciplinary teams of eskepras in real time for diagnostic purposes, will be easy to handle and integrate with the existing software.It will make it possible to reduce costs and provide personalised medical care, and will be used for remote learning and cooperation between experts, which in turn will be of interest to the new users of the system and will enable the development of the field of medical imaging.The system will be equipped with novel 4D image segmentation algorithms, image recording, machine learning and DCE analysis, which will help to improve the diagnostic performance of dynamic imaging.Innovative algorithms for advanced mapping of perfusion maps will allow new biomarkers to be extracted and analysed, and advanced statistical tools will allow in-depth analysis of extracted biomarkers.The aim of the project is to provide an innovative product to be implemented in daily clinical practice to improve the diagnosis and treatment of cancer patients. (English)
 
Property / summary: A dynamic contract on CT (‘DCE’) using CT and MRI is intensively studied in order to allow for an assessment of cancer and other tissues.It has been demonstrated that biomarkers that have been extracted from dynamic contrast trials correlate with physiological and molecular processes that can be observed in the angiogenesis of cancer.These biomarkers can be used to assess the characteristics and maturity of the cancer by stratifying the risk in patients with cancer.This project will establish an innovative system for a comprehensive DCE analysis.The aim of the project is to increase the effectiveness of diagnostic dynamic imaging by strengthening the contrast in personalised oncology by extraction of new and improved biomarkers.The system will allow interactive collaboration of interdisciplinary teams of eskepras in real time for diagnostic purposes, will be easy to handle and integrate with the existing software.It will make it possible to reduce costs and provide personalised medical care, and will be used for remote learning and cooperation between experts, which in turn will be of interest to the new users of the system and will enable the development of the field of medical imaging.The system will be equipped with novel 4D image segmentation algorithms, image recording, machine learning and DCE analysis, which will help to improve the diagnostic performance of dynamic imaging.Innovative algorithms for advanced mapping of perfusion maps will allow new biomarkers to be extracted and analysed, and advanced statistical tools will allow in-depth analysis of extracted biomarkers.The aim of the project is to provide an innovative product to be implemented in daily clinical practice to improve the diagnosis and treatment of cancer patients. (English) / rank
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Revision as of 10:32, 14 October 2020

Project in Poland financed by DG Regio
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English
Increase the diagnostic performance of dynamic imaging on a dynamic contrast in personalised oncology by extraction of new and improved biomarkers
Project in Poland financed by DG Regio

    Statements

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    9,000,832.76 zloty
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    2,160,199.86 Euro
    13 January 2020
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    19,445,026.24 zloty
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    4,666,806.30 Euro
    13 January 2020
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    46.29 percent
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    1 February 2016
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    31 December 2018
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    FUTURE PROCESSING SP. Z O.O.
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    50°34'7.3"N, 19°14'3.8"E
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    Obrazowanie dynamiczne po wzmocnieniu kontrastowym (ang. dynamic contrast enhanced imaging – DCE) przy użyciu tomografii komputerowej oraz rezonansu magnetycznego jest intensywnie badane w celu umożliwienia oceny unaczynienia nowotworów i innych tkanek. Wykazano, że biomarkery wyekstrahowane z badań dynamicznych po wzmocnieniu kontrastowym są skorelowane z procesami fizjologicznymi i molekularnymi, które można obserwować w angiogenezie nowotworowej. Biomarkery te mogą zostać wykorzystane do oceny charakterystyki i etapu zaawansowania nowotworu umożliwiając stratyfikację ryzyka u pacjentów z chorobą nowotworową. W ramach tego projektu zostanie stworzony innowacyjny system do kompleksowej analizy DCE. Celem projektu jest zwiększenie skuteczności diagnostycznej obrazowania dynamicznego po wzmocnieniu kontrastem w spersonalizowanej onkologii poprzez ekstrakcję nowych i ulepszonych biomarkerów. System będzie pozwalał na interaktywną współpracę interdyscyplinarnych zespołów eskeprtów w czasie rzeczywistym w celach diagnostycznych, będzie łatwy do obsługi i integracji z istniejącym oprogramowaniem. Umożliwi redukcję kosztów i pozwoli na zapewnienie spersonalizowanej opieki medycznej, oraz będzie mógł zostać użyty do zdalnej nauki i współpracy pomiędzy ekspertami, a to z kolei zainteresuje nowych użytkowników systemem oraz umożliwi rozwój dziedziny obrazowania medycznego. System będzie wyposażony w nowatorskie algorytmy segmentacji obrazów 4D, rejestracji obrazów, uczenia maszynowego oraz analizy DCE, które pomogą poprawić skuteczność diagnostyczną obrazowania dynamicznego. Innowacyjne algorytmy do zaawansowanej analizy map perfuzji pozwolą na ekstrakcję i analizę nowych biomarkerów, a zaawansowane narzędzia statystyczne pozwolą na dogłębną analizę wyekstrahowanych biomarkerów. Celem projektu jest dostarczenie innowacyjnego produktu, który zostanie wdrożony w codziennej praktyce klinicznej dla poprawienia skuteczności diagnozy i leczenia pacjentów z chorobami nowotworowymi. (Polish)
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    Identifiers

    POIR.01.02.00-00-0030/15
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