Citrus bioflavonoid hesperidin as anti-viral agent for SARS-CoV-2 (Q3988870): Difference between revisions

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Property / summary
 
Corona COVID-19 is a serious viral pandemic that has already infected many people. Therapeutic treatment is not yet possible. This project investigates an active substance from the peels of citrus fruits, the flavonoid hesperidine, which may be able to prevent and cure infections with SARS-CoV-2 virus. International scientists have shown through computer calculations that hesperidine blocks the virus in three different ways. Hesperidine prevents the attachment to human ACE2 receptors, prevents the virus from entering the cell, if the virus is still in the cell, then hesperidine prevents the virus from multiplying by preventing DNA reading and sabotaging the virus assembly into the cell.A research consortium led by the University of Groningen and regional SMEs will experimentally test this theoretical invention and also investigate the best uptake routes for hesperidine in the human body. Prototype products such as a hesperidine Citrus syrup, a hesperidine gel/cream and an inhaler are being developed. (English)
Property / summary: Corona COVID-19 is a serious viral pandemic that has already infected many people. Therapeutic treatment is not yet possible. This project investigates an active substance from the peels of citrus fruits, the flavonoid hesperidine, which may be able to prevent and cure infections with SARS-CoV-2 virus. International scientists have shown through computer calculations that hesperidine blocks the virus in three different ways. Hesperidine prevents the attachment to human ACE2 receptors, prevents the virus from entering the cell, if the virus is still in the cell, then hesperidine prevents the virus from multiplying by preventing DNA reading and sabotaging the virus assembly into the cell.A research consortium led by the University of Groningen and regional SMEs will experimentally test this theoretical invention and also investigate the best uptake routes for hesperidine in the human body. Prototype products such as a hesperidine Citrus syrup, a hesperidine gel/cream and an inhaler are being developed. (English) / rank
 
Normal rank
Property / summary: Corona COVID-19 is a serious viral pandemic that has already infected many people. Therapeutic treatment is not yet possible. This project investigates an active substance from the peels of citrus fruits, the flavonoid hesperidine, which may be able to prevent and cure infections with SARS-CoV-2 virus. International scientists have shown through computer calculations that hesperidine blocks the virus in three different ways. Hesperidine prevents the attachment to human ACE2 receptors, prevents the virus from entering the cell, if the virus is still in the cell, then hesperidine prevents the virus from multiplying by preventing DNA reading and sabotaging the virus assembly into the cell.A research consortium led by the University of Groningen and regional SMEs will experimentally test this theoretical invention and also investigate the best uptake routes for hesperidine in the human body. Prototype products such as a hesperidine Citrus syrup, a hesperidine gel/cream and an inhaler are being developed. (English) / qualifier
 
point in time: 15 December 2021
Timestamp+2021-12-15T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0

Revision as of 06:20, 15 December 2021

Project Q3988870 in Netherlands
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English
Citrus bioflavonoid hesperidin as anti-viral agent for SARS-CoV-2
Project Q3988870 in Netherlands

    Statements

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    416,665.0 Euro
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    1,100,832.232 Euro
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    37.85 percent
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    11 May 2020
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    31 May 2022
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    Color & Brain BV
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    9750 AA
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    9700 AB
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    Corona COVID-19 is een ernstige virale pandemie die reeds vele mensen heeft geïnfecteerd. Er is nog geen therapeutische behandeling mogelijk. Dit project onderzoekt een actieve stof uit de schillen van citrusvruchten, de flavonoïde hesperidine, die mogelijkerwijs infecties met SARS-CoV-2 virus kan voorkomen en genezen. Internationale wetenschappers hebben via computerberekeningen laten zien dat hesperidine op drie verschillende manieren het virus blokkeert. Hesperidine voorkomt het aanhechten aan menselijk ACE2 receptoren, het voorkomt dat het virus de cel binnendringt, als het virus toch in de cel is, dan voorkomt hesperidine dat het virus zich kan vermenigvuldigen door het DNA aflezen te voorkomen en de virus assemblage inde cel te saboteren.Een onderzoek consortium onder leiding van de Rijksuniversiteit Groningen en regionaal MKB gaan deze theoretische vinding experimenteel testen en onderzoeken tevens de beste opname routes voor hesperidine in het menselijk lichaam. Hiervoor worden prototype producten zoals een hesperidine Citrus-siroop, een hesperidine gel/crème en een inhalator ontwikkeld. (Dutch)
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    Corona COVID-19 is a serious viral pandemic that has already infected many people. Therapeutic treatment is not yet possible. This project investigates an active substance from the peels of citrus fruits, the flavonoid hesperidine, which may be able to prevent and cure infections with SARS-CoV-2 virus. International scientists have shown through computer calculations that hesperidine blocks the virus in three different ways. Hesperidine prevents the attachment to human ACE2 receptors, prevents the virus from entering the cell, if the virus is still in the cell, then hesperidine prevents the virus from multiplying by preventing DNA reading and sabotaging the virus assembly into the cell.A research consortium led by the University of Groningen and regional SMEs will experimentally test this theoretical invention and also investigate the best uptake routes for hesperidine in the human body. Prototype products such as a hesperidine Citrus syrup, a hesperidine gel/cream and an inhaler are being developed. (English)
    15 December 2021
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    Identifiers

    OP-2014-2023-Noord-OPSNN0315
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