Q3179342 (Q3179342): Difference between revisions
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(Created claim: summary (P836): The general objectives: Describe the diagnostic process of oropharyngeal cancer COF from the first symptom(s) to the diagnosis and initiation of treatment and establish the time intervals dependent on the patient, the professional and the healthcare system. Also identifying factors associated with diagnostic delay and at time intervals of the process. As well as to evaluate the risk that long first symptom-definitive diagnostic intervals (diagno...) |
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The general objectives: Describe the diagnostic process of oropharyngeal cancer COF from the first symptom(s) to the diagnosis and initiation of treatment and establish the time intervals dependent on the patient, the professional and the healthcare system. Also identifying factors associated with diagnostic delay and at time intervals of the process. As well as to evaluate the risk that long first symptom-definitive diagnostic intervals (diagnostic delay) may encourage diagnosis to be established in advanced stages of the disease. Methodology: We have designed a cross-sectional study, considering this study as a variant of a case-control study in terms of sample calculation, analysis and presentation of results. The COF included will be cases of cancer with histological diagnosis of FOC diagnosed during the inclusion period (2.5 years) in the CHUAC (Coruña), Hospital Povisa (Vigo) and Facultad Medicina-Odontologia (Santiago de Compostela), which have open history in a health center in their health areas. These hospitals serve as reference to 24 minor hospitals, 356 health centres and 1797000 inhabitants. The variables studied will be the patient’s sociodemographic and clinical variables, those specific to the tumor (type, degree of malignancy, Ki-67, p14, p21, p27, PRB, Caderin E, CD44, matrix metalloproteinases, Bax), and the health system Odds Ratio will be used as a measure of association between intervals and MRT at the time of diagnosis. (English) | |||||||||||||||
| Property / summary: The general objectives: Describe the diagnostic process of oropharyngeal cancer COF from the first symptom(s) to the diagnosis and initiation of treatment and establish the time intervals dependent on the patient, the professional and the healthcare system. Also identifying factors associated with diagnostic delay and at time intervals of the process. As well as to evaluate the risk that long first symptom-definitive diagnostic intervals (diagnostic delay) may encourage diagnosis to be established in advanced stages of the disease. Methodology: We have designed a cross-sectional study, considering this study as a variant of a case-control study in terms of sample calculation, analysis and presentation of results. The COF included will be cases of cancer with histological diagnosis of FOC diagnosed during the inclusion period (2.5 years) in the CHUAC (Coruña), Hospital Povisa (Vigo) and Facultad Medicina-Odontologia (Santiago de Compostela), which have open history in a health center in their health areas. These hospitals serve as reference to 24 minor hospitals, 356 health centres and 1797000 inhabitants. The variables studied will be the patient’s sociodemographic and clinical variables, those specific to the tumor (type, degree of malignancy, Ki-67, p14, p21, p27, PRB, Caderin E, CD44, matrix metalloproteinases, Bax), and the health system Odds Ratio will be used as a measure of association between intervals and MRT at the time of diagnosis. (English) / rank | |||||||||||||||
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| Property / summary: The general objectives: Describe the diagnostic process of oropharyngeal cancer COF from the first symptom(s) to the diagnosis and initiation of treatment and establish the time intervals dependent on the patient, the professional and the healthcare system. Also identifying factors associated with diagnostic delay and at time intervals of the process. As well as to evaluate the risk that long first symptom-definitive diagnostic intervals (diagnostic delay) may encourage diagnosis to be established in advanced stages of the disease. Methodology: We have designed a cross-sectional study, considering this study as a variant of a case-control study in terms of sample calculation, analysis and presentation of results. The COF included will be cases of cancer with histological diagnosis of FOC diagnosed during the inclusion period (2.5 years) in the CHUAC (Coruña), Hospital Povisa (Vigo) and Facultad Medicina-Odontologia (Santiago de Compostela), which have open history in a health center in their health areas. These hospitals serve as reference to 24 minor hospitals, 356 health centres and 1797000 inhabitants. The variables studied will be the patient’s sociodemographic and clinical variables, those specific to the tumor (type, degree of malignancy, Ki-67, p14, p21, p27, PRB, Caderin E, CD44, matrix metalloproteinases, Bax), and the health system Odds Ratio will be used as a measure of association between intervals and MRT at the time of diagnosis. (English) / qualifier | |||||||||||||||
point in time: 12 October 2021
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Revision as of 19:03, 12 October 2021
Project Q3179342 in Spain
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | No label defined |
Project Q3179342 in Spain |
Statements
41,200.0 Euro
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51,500.0 Euro
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80.0 percent
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1 January 2015
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31 March 2019
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FUNDACION INSTITUTO DE INVESTIGACION SANITARIA DE SANTIAGO DE COMPOSTELA
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43°2'46.39"N, 7°28'26.36"W
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27028
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Los objetivos generales: Describir el proceso diagnóstico del cáncer oro-faringeo COF desde el primer síntoma/s hasta el diagnóstico e inicio del tratamiento y establecer los intervalos temporales dependientes del paciente, el profesional y el sistema sanitario. También el identificar factores asociados al retraso diagnóstico y a intervalos temporales del proceso. Así como evaluar el riesgo de que largos intervalos primer síntoma- diagnóstico definitivo (retraso diagnóstico) favorezcan que los diagnósticos se establezcan en fases avanzadas de la enfermedad. Metodología: Hemos diseñado un estudio de carácter transversal, considerando este estudio como una variante de un estudio de casos y controles en lo referente a cálculo de muestra, análisis y presentación de resultados. Los COF incluidos serán casos incidentes de cáncer con diagnóstico histológico de COF diagnosticados durante el período de inclusión (2,5 años) en el CHUAC (Coruña), Hospital POVISA (Vigo) y Facultad Medicina-Odontologia (Santiago de Compostela), que tengan historia abierta en un centro de salud de sus áreas sanitarias. Estos Hospitales sirven de referencia a 24 hospitales menores, 356 centros de salud y 1797000 habitantes. Las variables estudiadas serán las sociodemográficas y clínicas del paciente, las propias del tumor (tipo, grado de malignidad, Ki-67, p14,p21,p27,PRb, Caderina E, CD44, metaloproteinasas de matriz, Bax),y del sistema sanitario Se utilizará el Odds Ratio como medida de asociación entre intervalos y TNM en el momento del diagnóstico. (Spanish)
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The general objectives: Describe the diagnostic process of oropharyngeal cancer COF from the first symptom(s) to the diagnosis and initiation of treatment and establish the time intervals dependent on the patient, the professional and the healthcare system. Also identifying factors associated with diagnostic delay and at time intervals of the process. As well as to evaluate the risk that long first symptom-definitive diagnostic intervals (diagnostic delay) may encourage diagnosis to be established in advanced stages of the disease. Methodology: We have designed a cross-sectional study, considering this study as a variant of a case-control study in terms of sample calculation, analysis and presentation of results. The COF included will be cases of cancer with histological diagnosis of FOC diagnosed during the inclusion period (2.5 years) in the CHUAC (Coruña), Hospital Povisa (Vigo) and Facultad Medicina-Odontologia (Santiago de Compostela), which have open history in a health center in their health areas. These hospitals serve as reference to 24 minor hospitals, 356 health centres and 1797000 inhabitants. The variables studied will be the patient’s sociodemographic and clinical variables, those specific to the tumor (type, degree of malignancy, Ki-67, p14, p21, p27, PRB, Caderin E, CD44, matrix metalloproteinases, Bax), and the health system Odds Ratio will be used as a measure of association between intervals and MRT at the time of diagnosis. (English)
12 October 2021
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Lugo
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Identifiers
PI14_01446
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