A RICE CELL MODERNISED FOR RESEARCH IN SYNTHETIC BIOLOGY AND ITS APPLICATIONS (Q3169370): Difference between revisions

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(‎Changed label, description and/or aliases in en: translated_label)
(‎Removed claim: summary (P836): THE PROJECT (RETRICELL) HAS A FUNDAMENTAL OBJECTIVE: CREATE NEW VIABLE CELLS, FOR INDUSTRIAL USE AND PLANTS WITH PROFOUND CHANGES IN THEIR MOLECULAR AND BIOSYNTHETIC MECHANISMS. THIS OBJECTIVE IS BASED ON OUR RESEARCH OF FUNDAMENTAL REGULATORY MECHANISMS AND THEIR APPLICATION IN THIS PROJECT WILL HELP US SOLVE THE CRITICAL POINTS THAT PREVENT THE FULL APPLICATION OF THE SYNTHETIC BIOLOGY IN PLANTS. THE STARTING POINT OF RETRICELL ARE PRELIMINA...)
Property / summary
THE PROJECT (RETRICELL) HAS A FUNDAMENTAL OBJECTIVE: CREATE NEW VIABLE CELLS, FOR INDUSTRIAL USE AND PLANTS WITH PROFOUND CHANGES IN THEIR MOLECULAR AND BIOSYNTHETIC MECHANISMS. THIS OBJECTIVE IS BASED ON OUR RESEARCH OF FUNDAMENTAL REGULATORY MECHANISMS AND THEIR APPLICATION IN THIS PROJECT WILL HELP US SOLVE THE CRITICAL POINTS THAT PREVENT THE FULL APPLICATION OF THE SYNTHETIC BIOLOGY IN PLANTS. THE STARTING POINT OF RETRICELL ARE PRELIMINARY RESULTS BASED ON THE OBVENCION OF A PARTIALLY REORGANISED RICE CELL THAT WOULD ALLOW THE ACCUMULATION OF CARBON AND ENERGY BY FAVORING ITS DIVERSION TO OTHER ROUTES WITHOUT RISKING THE VIABILITY OF THE CELL AND THE RESULTING PLANTS. AT THE LEVEL OF BASIC RESEARCH, THE PROJECT PROPOSES TO MODIFY THE NETWORKS OF BASIC METABOLISM AND DEREGULATE THE FORMATION OF KEY PRECURSORS, EVENTUALLY RECONSTITUTING A HETEROLOGOUS ROUTE WITH INDUSTRIAL APPLICATIONS, AS A DEMONSTRATION OF THE CONCEPT. DEDIFFERENTIATED CELLS OF RICE AND PLANTS, WILL ALLOW RETRICELL TO ADDRESS FUNDAMENTAL BIOLOGICAL ISSUES NECESSARY TO ESTABLISH THE BASIS FOR MOVING TOWARDS A PRACTICAL APPLICATION. _x000D_ is treated for an AMBICIOSA PROPOSAL, BUT REALISTA, BASED IN PRELIMINARY RESULTS AND IN THE EXPERIENCE OF THE GROUP TO LIVE TO CABO COMMITTEE PROGRAMMS OF COMPLEMENTS IN CEREALES. THE PROPOSED PROJECT IS HIGH-RISK BUT, AT THE SAME TIME, CAN BRING GREAT BENEFITS, AND IF IT SUCCEEDS, EITHER FULLY OR IN PART, IT WILL LEAD TO ADVANCES THAT WILL HELP SCIENCE, IN A NUMBER OF DIFFERENT AND IMPORTANT AREAS. THESE ARE DISCUSSED IN DETAIL IN THE PROJECT. OUR APPROACH OFFERS A UNIQUE AND INNOVATIVE OPPORTUNITY TO IMPROVE THE CURRENT LIMITS THAT HAVE SO FAR PREVENTED THE APPLICATION OF THE SYNTHETIC BIOLOGY, UNLOCKING THE POTENTIAL OF THE PLANT AS A MANUFACTURER USEFUL FOR THE EXPLOITATION OF ITS QUIMIODIVERSITY FOR INDUSTRIAL PURPOSE. THE PROPOSAL IS OF HIGH INTEREST TO INDUSTRY FOR TWO REASONS: FIRST, THE TECHNOLOGIES DEVELOPED DURING THE PROJECT AND THE INTELLECTUAL PROPERTY GENERATED ARE OF RELEVANCE NOT ONLY TO PLANTS BUT ALSO TO MICROORGANISMS. SECONDLY, TO DEMONSTRATE THE CONCEPT THAT PHYTOSTEROLS, IMPORTANT NUTRITIONALLY, ARE OF GREAT INTEREST TO THE NUTRACEUTICAL AND PHARMACEUTICAL INDUSTRIES AND WE WILL TAKE ADVANTAGE OF THIS INTEREST TO ATTRACT GREATER COMMERCIAL PARTICIPATION IN THE PROJECT (English)
 
Property / summary: THE PROJECT (RETRICELL) HAS A FUNDAMENTAL OBJECTIVE: CREATE NEW VIABLE CELLS, FOR INDUSTRIAL USE AND PLANTS WITH PROFOUND CHANGES IN THEIR MOLECULAR AND BIOSYNTHETIC MECHANISMS. THIS OBJECTIVE IS BASED ON OUR RESEARCH OF FUNDAMENTAL REGULATORY MECHANISMS AND THEIR APPLICATION IN THIS PROJECT WILL HELP US SOLVE THE CRITICAL POINTS THAT PREVENT THE FULL APPLICATION OF THE SYNTHETIC BIOLOGY IN PLANTS. THE STARTING POINT OF RETRICELL ARE PRELIMINARY RESULTS BASED ON THE OBVENCION OF A PARTIALLY REORGANISED RICE CELL THAT WOULD ALLOW THE ACCUMULATION OF CARBON AND ENERGY BY FAVORING ITS DIVERSION TO OTHER ROUTES WITHOUT RISKING THE VIABILITY OF THE CELL AND THE RESULTING PLANTS. AT THE LEVEL OF BASIC RESEARCH, THE PROJECT PROPOSES TO MODIFY THE NETWORKS OF BASIC METABOLISM AND DEREGULATE THE FORMATION OF KEY PRECURSORS, EVENTUALLY RECONSTITUTING A HETEROLOGOUS ROUTE WITH INDUSTRIAL APPLICATIONS, AS A DEMONSTRATION OF THE CONCEPT. DEDIFFERENTIATED CELLS OF RICE AND PLANTS, WILL ALLOW RETRICELL TO ADDRESS FUNDAMENTAL BIOLOGICAL ISSUES NECESSARY TO ESTABLISH THE BASIS FOR MOVING TOWARDS A PRACTICAL APPLICATION. _x000D_ is treated for an AMBICIOSA PROPOSAL, BUT REALISTA, BASED IN PRELIMINARY RESULTS AND IN THE EXPERIENCE OF THE GROUP TO LIVE TO CABO COMMITTEE PROGRAMMS OF COMPLEMENTS IN CEREALES. THE PROPOSED PROJECT IS HIGH-RISK BUT, AT THE SAME TIME, CAN BRING GREAT BENEFITS, AND IF IT SUCCEEDS, EITHER FULLY OR IN PART, IT WILL LEAD TO ADVANCES THAT WILL HELP SCIENCE, IN A NUMBER OF DIFFERENT AND IMPORTANT AREAS. THESE ARE DISCUSSED IN DETAIL IN THE PROJECT. OUR APPROACH OFFERS A UNIQUE AND INNOVATIVE OPPORTUNITY TO IMPROVE THE CURRENT LIMITS THAT HAVE SO FAR PREVENTED THE APPLICATION OF THE SYNTHETIC BIOLOGY, UNLOCKING THE POTENTIAL OF THE PLANT AS A MANUFACTURER USEFUL FOR THE EXPLOITATION OF ITS QUIMIODIVERSITY FOR INDUSTRIAL PURPOSE. THE PROPOSAL IS OF HIGH INTEREST TO INDUSTRY FOR TWO REASONS: FIRST, THE TECHNOLOGIES DEVELOPED DURING THE PROJECT AND THE INTELLECTUAL PROPERTY GENERATED ARE OF RELEVANCE NOT ONLY TO PLANTS BUT ALSO TO MICROORGANISMS. SECONDLY, TO DEMONSTRATE THE CONCEPT THAT PHYTOSTEROLS, IMPORTANT NUTRITIONALLY, ARE OF GREAT INTEREST TO THE NUTRACEUTICAL AND PHARMACEUTICAL INDUSTRIES AND WE WILL TAKE ADVANTAGE OF THIS INTEREST TO ATTRACT GREATER COMMERCIAL PARTICIPATION IN THE PROJECT (English) / rank
Normal rank
 
Property / summary: THE PROJECT (RETRICELL) HAS A FUNDAMENTAL OBJECTIVE: CREATE NEW VIABLE CELLS, FOR INDUSTRIAL USE AND PLANTS WITH PROFOUND CHANGES IN THEIR MOLECULAR AND BIOSYNTHETIC MECHANISMS. THIS OBJECTIVE IS BASED ON OUR RESEARCH OF FUNDAMENTAL REGULATORY MECHANISMS AND THEIR APPLICATION IN THIS PROJECT WILL HELP US SOLVE THE CRITICAL POINTS THAT PREVENT THE FULL APPLICATION OF THE SYNTHETIC BIOLOGY IN PLANTS. THE STARTING POINT OF RETRICELL ARE PRELIMINARY RESULTS BASED ON THE OBVENCION OF A PARTIALLY REORGANISED RICE CELL THAT WOULD ALLOW THE ACCUMULATION OF CARBON AND ENERGY BY FAVORING ITS DIVERSION TO OTHER ROUTES WITHOUT RISKING THE VIABILITY OF THE CELL AND THE RESULTING PLANTS. AT THE LEVEL OF BASIC RESEARCH, THE PROJECT PROPOSES TO MODIFY THE NETWORKS OF BASIC METABOLISM AND DEREGULATE THE FORMATION OF KEY PRECURSORS, EVENTUALLY RECONSTITUTING A HETEROLOGOUS ROUTE WITH INDUSTRIAL APPLICATIONS, AS A DEMONSTRATION OF THE CONCEPT. DEDIFFERENTIATED CELLS OF RICE AND PLANTS, WILL ALLOW RETRICELL TO ADDRESS FUNDAMENTAL BIOLOGICAL ISSUES NECESSARY TO ESTABLISH THE BASIS FOR MOVING TOWARDS A PRACTICAL APPLICATION. _x000D_ is treated for an AMBICIOSA PROPOSAL, BUT REALISTA, BASED IN PRELIMINARY RESULTS AND IN THE EXPERIENCE OF THE GROUP TO LIVE TO CABO COMMITTEE PROGRAMMS OF COMPLEMENTS IN CEREALES. THE PROPOSED PROJECT IS HIGH-RISK BUT, AT THE SAME TIME, CAN BRING GREAT BENEFITS, AND IF IT SUCCEEDS, EITHER FULLY OR IN PART, IT WILL LEAD TO ADVANCES THAT WILL HELP SCIENCE, IN A NUMBER OF DIFFERENT AND IMPORTANT AREAS. THESE ARE DISCUSSED IN DETAIL IN THE PROJECT. OUR APPROACH OFFERS A UNIQUE AND INNOVATIVE OPPORTUNITY TO IMPROVE THE CURRENT LIMITS THAT HAVE SO FAR PREVENTED THE APPLICATION OF THE SYNTHETIC BIOLOGY, UNLOCKING THE POTENTIAL OF THE PLANT AS A MANUFACTURER USEFUL FOR THE EXPLOITATION OF ITS QUIMIODIVERSITY FOR INDUSTRIAL PURPOSE. THE PROPOSAL IS OF HIGH INTEREST TO INDUSTRY FOR TWO REASONS: FIRST, THE TECHNOLOGIES DEVELOPED DURING THE PROJECT AND THE INTELLECTUAL PROPERTY GENERATED ARE OF RELEVANCE NOT ONLY TO PLANTS BUT ALSO TO MICROORGANISMS. SECONDLY, TO DEMONSTRATE THE CONCEPT THAT PHYTOSTEROLS, IMPORTANT NUTRITIONALLY, ARE OF GREAT INTEREST TO THE NUTRACEUTICAL AND PHARMACEUTICAL INDUSTRIES AND WE WILL TAKE ADVANTAGE OF THIS INTEREST TO ATTRACT GREATER COMMERCIAL PARTICIPATION IN THE PROJECT (English) / qualifier
point in time: 12 October 2021
Timestamp+2021-10-12T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
 

Revision as of 18:18, 12 October 2021

Project Q3169370 in Spain
Language Label Description Also known as
English
A RICE CELL MODERNISED FOR RESEARCH IN SYNTHETIC BIOLOGY AND ITS APPLICATIONS
Project Q3169370 in Spain

    Statements

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    145,200.0 Euro
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    290,400.0 Euro
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    50.0 percent
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    1 January 2015
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    31 December 2018
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    UNIVERSIDAD DE LERIDA
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    41°36'53.14"N, 0°37'36.41"E
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    25120
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    EL PROYECTO (RETRICELL) TIENE UN OBJETIVO FUNDAMENTAL: CREAR NUEVAS CELULAS VIABLES, PARA USO INDUSTRIAL Y PLANTAS CON PROFUNDOS CAMBIOS EN SUS MECANISMOS MOLECULARES Y BIOSINTETICOS. ESTE OBJETIVO ESTA BASADO EN NUESTRAS INVESTIGACIONES DE LOS MECANISMOS FUNDAMENTALES REGULADORES Y SU APLICACION EN ESTE PROYECTO NOS AYUDARA A RESOLVER LOS PUNTOS CRITICOS QUE IMPIDEN LA PLENA APLICACION DE LA BIOLOGIA SINTETICA EN PLANTAS. EL PUNTO DE PARTIDA DE RETRICELL SON RESULTADOS PRELIMINARES BASADOS EN LA OBVENCION DE UN CELULA DE ARROZ PARCIALMENTE ¿REORGANIZADA¿ QUE PERMITIRA LA ACUMULACION DE CARBONO Y ENERGIA FAVORECIENDO SU DESVIO HACIA OTRAS VIAS SIN ARRIESGAR LA VIABILIDAD DE LA CELULA Y LAS PLANTAS RESULTANTES. A NIVEL DE INVESTIGACION BASICA, EL PROYECTO PROPONE MODIFICAR LAS REDES DEL METABOLISMO BASICO Y DESREGULAR LA FORMACION DE PRECURSORES CLAVE, RECONSTITUYENDO FINALMENTE UNA VIA HETEROLOGA CON APLICACIONES INDUSTRIALES, COMO DEMOSTRACION DEL CONCEPTO. CELULAS DESDIFERENCIADAS DE ARROZ Y PLANTAS, PERMITIRAN A RETRICELL ABORDAR CUESTIONES BIOLOGICAS FUNDAMENTALES NECESARIAS PARA ESTABLECER LA BASE QUE AVANCE HACIA UNA APLICACION PRACTICA. _x000D_ SE TRATA DE UNA PROPUESTA AMBICIOSA, PERO REALISTA, BASADA EN RESULTADOS PRELIMINARES Y EN LA EXPERIENCIA DEL GRUPO PARA LLEVAR A CABO PROGRAMAS DE INGENIERIA METABOLICA COMPLEJOS EN CEREALES. EL PROYECTO PROPUESTO ES DE ALTO RIESGO PERO, A LA VEZ, PUEDE APORTAR GRANDES BENEFICIOS, Y SI TIENE EXITO, YA SEA TOTALMENTE O EN PARTE, DARA LUGAR A AVANCES QUE AYUDARAN A LA CIENCIA, EN UN NUMERO DE AREAS DIFERENTES E IMPORTANTES. ESTOS SE DISCUTEN EN DETALLE EN EL PROYECTO. NUESTRO ENFOQUE OFRECE UNA OPORTUNIDAD UNICA E INNOVADORA PARA MEJORAR LOS LIMITES ACTUALES QUE HASTA AHORA HAN IMPEDIDO LA APLICACION DE LA BIOLOGIA SINTETICA, DESBLOQUEANDO EL POTENCIAL DE LA PLANTA COMO UNA ¿FABRICA¿ UTIL PARA LA EXPLOTACION DE SU QUIMIODIVERSIDAD CON FINALIDAD INDUSTRIAL. LA PROPUESTA ES DE ELEVADO INTERES PARA LA INDUSTRIA POR DOS MOTIVOS: EN PRIMER LUGAR LAS TECNOLOGIAS QUE SE DESARROLLARAN EN EL TRANSCURSO DEL PROYECTO Y DE LA PROPIEDAD INTELECTUAL GENERADAS SON DE RELEVANCIA NO SOLO PARA LAS PLANTAS SINO TAMBIEN PARA LOS MICROORGANISMOS. EN SEGUNDO LUGAR EL DEMOSTRAR EL CONCEPTO DE QUE LOS FITOESTEROLES, IMPORTANTES NUTRICIONALMENTE, SON ADEMAS DE GRAN INTERES PARA LAS INDUSTRIAS DE NUTRACEUTICAS Y FARMACEUTICAS Y VAMOS A APROVECHAR ESTE INTERES PARA ATRAER UNA MAYOR PARTICIPACION COMERCIAL EN EL PROYECTO (Spanish)
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    Lleida
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    Identifiers

    BIO2014-54426-P
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