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(Created claim: summary (P836): The aim of the project is to develop high value-added biologically active compounds, potentially usable in cosmetics, with a characteristic safety and efficacy profile, from the processing of medicinal plants (Matricaria) and by-products of in vitro cell (Dracocephalum, Ribes and Juniperus) cultivation using the most advanced technologies of supercritical fluid extraction and fractionation. The project consists of six key actions:1. Extract...) |
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The aim of the project is to develop high value-added biologically active compounds, potentially usable in cosmetics, with a characteristic safety and efficacy profile, from the processing of medicinal plants (Matricaria) and by-products of in vitro cell (Dracocephalum, Ribes and Juniperus) cultivation using the most advanced technologies of supercritical fluid extraction and fractionation. The project consists of six key actions:1. Extraction of biologically active compounds from therapeutic plant processing and by-products of in vitro cell culture using supercritical fluid extraction (SFE) with supercritical carbon dioxide resulting in extraction methodology (extraction protocol).2. Fractionation of polar and non-polar compounds from extracts of supercritical fluid from herb processing; In vitro cell cultivation resulting in a fractionation methodology prototype (fractionation protocol).3. Chemical characterisation of extractions and fractions using qualitative and quantitative screening of biologically active phytochemical classes as well as the identification of predominant biologically active compounds using related methods (one phytochemical screening protocol, one identification protocol for biologically active compounds).4. Biological activity of extracts and fractions of by-products from the manufacture of medicinal plants and in vitro plant cell cultures (reports of cytotoxicity and phototoxicity tests; Antimicrobial activity testing reports; Test reports for skin protective activity of 10 extracts and fractions).5. Combination of biorefining fractions and extracts (from activities WP1 and WP2) to obtain combinations of high biological activity ingredients in cosmetic products (the prototype of the ingredient of the cosmetic product of the TRL 4).6. Project management and communication will focus on effective management and knowledge transfer to the general public, to the scientific community and to specialists. The results will be disseminated by publishing three articles in Open Access scientific journals, making six presentations at international conferences and informing the public via the Internet, social media and information activities. This is an industrial research project, related to the economic activities of biotechnology and bioeconomy, and is carried out by a cross-sectoral consortium: Institute for Environmental Solutions (VRI) (the main partner) is a scientific institution, an international network of scientists, artists, engineers and specialists who care for the environment. The Institute has established multidisciplinary teams to develop and develop tailor-made innovative environmental solutions. In recent years extensive knowledge has been gained from various projects on the research, analysis and testing of various plant species, including medicinal plants and their practices, such as essential oils, flower water and herbs, as well as the development of data-based solutions for the assessment of natural resources. The Institute is also an active member of the European Herb Growers Association.• SIA Field and Forest (FAF) is a certified organic farming company. It currently owns 338 ha of agricultural land and 644 hectares of forest land. More than 80 % of agricultural land is cultivated with medicinal and aromatic plants. The company is one of the largest organic camomile growers and producers in Eastern Europe. The FAF currently develops AAA essential oils and flower water distillation methods in industrial volumes in order to increase the added value of these products. The company is also introducing an innovative extraction of liquefied freon gas (phytosol extraction) from unconventional aromatic plants in experimental volumes.• Alternative Plants (AP) is currently the only company in the Baltic States that uses plant cell cultivation technology to produce biologically active cosmetic raw materials. The HR focuses on medicinal plants that are difficult to grow, which are rare or at risk. The AP is a company with experience in the creation of plant cell cultures, promoting the production of certain chemical compounds, using chemical and physical agents and expanding cell cultivation. Up to the sims, the AP has developed 8 different cell cultures, two of which are expanded. Components derived from plant cell biomass are characterised and their biological activity tested. At present, the EaP has created three different products. The AP has extensive experience in the development of anti-microbial and antioxidative substances. Product ‘cosmetic active ingredient’: a composition consisting of a combination of different extracts or fractions of by-products (prototype – corresponding to the evaluation of TRL4 high value added composite components of cosmetic products;3.825. FTE jobs in private organisations; EUR215 624.15 private R & D funding;Three public (English) | |||||||||||||||
| Property / summary: The aim of the project is to develop high value-added biologically active compounds, potentially usable in cosmetics, with a characteristic safety and efficacy profile, from the processing of medicinal plants (Matricaria) and by-products of in vitro cell (Dracocephalum, Ribes and Juniperus) cultivation using the most advanced technologies of supercritical fluid extraction and fractionation. The project consists of six key actions:1. Extraction of biologically active compounds from therapeutic plant processing and by-products of in vitro cell culture using supercritical fluid extraction (SFE) with supercritical carbon dioxide resulting in extraction methodology (extraction protocol).2. Fractionation of polar and non-polar compounds from extracts of supercritical fluid from herb processing; In vitro cell cultivation resulting in a fractionation methodology prototype (fractionation protocol).3. Chemical characterisation of extractions and fractions using qualitative and quantitative screening of biologically active phytochemical classes as well as the identification of predominant biologically active compounds using related methods (one phytochemical screening protocol, one identification protocol for biologically active compounds).4. Biological activity of extracts and fractions of by-products from the manufacture of medicinal plants and in vitro plant cell cultures (reports of cytotoxicity and phototoxicity tests; Antimicrobial activity testing reports; Test reports for skin protective activity of 10 extracts and fractions).5. Combination of biorefining fractions and extracts (from activities WP1 and WP2) to obtain combinations of high biological activity ingredients in cosmetic products (the prototype of the ingredient of the cosmetic product of the TRL 4).6. Project management and communication will focus on effective management and knowledge transfer to the general public, to the scientific community and to specialists. The results will be disseminated by publishing three articles in Open Access scientific journals, making six presentations at international conferences and informing the public via the Internet, social media and information activities. This is an industrial research project, related to the economic activities of biotechnology and bioeconomy, and is carried out by a cross-sectoral consortium: Institute for Environmental Solutions (VRI) (the main partner) is a scientific institution, an international network of scientists, artists, engineers and specialists who care for the environment. The Institute has established multidisciplinary teams to develop and develop tailor-made innovative environmental solutions. In recent years extensive knowledge has been gained from various projects on the research, analysis and testing of various plant species, including medicinal plants and their practices, such as essential oils, flower water and herbs, as well as the development of data-based solutions for the assessment of natural resources. The Institute is also an active member of the European Herb Growers Association.• SIA Field and Forest (FAF) is a certified organic farming company. It currently owns 338 ha of agricultural land and 644 hectares of forest land. More than 80 % of agricultural land is cultivated with medicinal and aromatic plants. The company is one of the largest organic camomile growers and producers in Eastern Europe. The FAF currently develops AAA essential oils and flower water distillation methods in industrial volumes in order to increase the added value of these products. The company is also introducing an innovative extraction of liquefied freon gas (phytosol extraction) from unconventional aromatic plants in experimental volumes.• Alternative Plants (AP) is currently the only company in the Baltic States that uses plant cell cultivation technology to produce biologically active cosmetic raw materials. The HR focuses on medicinal plants that are difficult to grow, which are rare or at risk. The AP is a company with experience in the creation of plant cell cultures, promoting the production of certain chemical compounds, using chemical and physical agents and expanding cell cultivation. Up to the sims, the AP has developed 8 different cell cultures, two of which are expanded. Components derived from plant cell biomass are characterised and their biological activity tested. At present, the EaP has created three different products. The AP has extensive experience in the development of anti-microbial and antioxidative substances. Product ‘cosmetic active ingredient’: a composition consisting of a combination of different extracts or fractions of by-products (prototype – corresponding to the evaluation of TRL4 high value added composite components of cosmetic products;3.825. FTE jobs in private organisations; EUR215 624.15 private R & D funding;Three public (English) / rank | |||||||||||||||
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| Property / summary: The aim of the project is to develop high value-added biologically active compounds, potentially usable in cosmetics, with a characteristic safety and efficacy profile, from the processing of medicinal plants (Matricaria) and by-products of in vitro cell (Dracocephalum, Ribes and Juniperus) cultivation using the most advanced technologies of supercritical fluid extraction and fractionation. The project consists of six key actions:1. Extraction of biologically active compounds from therapeutic plant processing and by-products of in vitro cell culture using supercritical fluid extraction (SFE) with supercritical carbon dioxide resulting in extraction methodology (extraction protocol).2. Fractionation of polar and non-polar compounds from extracts of supercritical fluid from herb processing; In vitro cell cultivation resulting in a fractionation methodology prototype (fractionation protocol).3. Chemical characterisation of extractions and fractions using qualitative and quantitative screening of biologically active phytochemical classes as well as the identification of predominant biologically active compounds using related methods (one phytochemical screening protocol, one identification protocol for biologically active compounds).4. Biological activity of extracts and fractions of by-products from the manufacture of medicinal plants and in vitro plant cell cultures (reports of cytotoxicity and phototoxicity tests; Antimicrobial activity testing reports; Test reports for skin protective activity of 10 extracts and fractions).5. Combination of biorefining fractions and extracts (from activities WP1 and WP2) to obtain combinations of high biological activity ingredients in cosmetic products (the prototype of the ingredient of the cosmetic product of the TRL 4).6. Project management and communication will focus on effective management and knowledge transfer to the general public, to the scientific community and to specialists. The results will be disseminated by publishing three articles in Open Access scientific journals, making six presentations at international conferences and informing the public via the Internet, social media and information activities. This is an industrial research project, related to the economic activities of biotechnology and bioeconomy, and is carried out by a cross-sectoral consortium: Institute for Environmental Solutions (VRI) (the main partner) is a scientific institution, an international network of scientists, artists, engineers and specialists who care for the environment. The Institute has established multidisciplinary teams to develop and develop tailor-made innovative environmental solutions. In recent years extensive knowledge has been gained from various projects on the research, analysis and testing of various plant species, including medicinal plants and their practices, such as essential oils, flower water and herbs, as well as the development of data-based solutions for the assessment of natural resources. The Institute is also an active member of the European Herb Growers Association.• SIA Field and Forest (FAF) is a certified organic farming company. It currently owns 338 ha of agricultural land and 644 hectares of forest land. More than 80 % of agricultural land is cultivated with medicinal and aromatic plants. The company is one of the largest organic camomile growers and producers in Eastern Europe. The FAF currently develops AAA essential oils and flower water distillation methods in industrial volumes in order to increase the added value of these products. The company is also introducing an innovative extraction of liquefied freon gas (phytosol extraction) from unconventional aromatic plants in experimental volumes.• Alternative Plants (AP) is currently the only company in the Baltic States that uses plant cell cultivation technology to produce biologically active cosmetic raw materials. The HR focuses on medicinal plants that are difficult to grow, which are rare or at risk. The AP is a company with experience in the creation of plant cell cultures, promoting the production of certain chemical compounds, using chemical and physical agents and expanding cell cultivation. Up to the sims, the AP has developed 8 different cell cultures, two of which are expanded. Components derived from plant cell biomass are characterised and their biological activity tested. At present, the EaP has created three different products. The AP has extensive experience in the development of anti-microbial and antioxidative substances. Product ‘cosmetic active ingredient’: a composition consisting of a combination of different extracts or fractions of by-products (prototype – corresponding to the evaluation of TRL4 high value added composite components of cosmetic products;3.825. FTE jobs in private organisations; EUR215 624.15 private R & D funding;Three public (English) / qualifier | |||||||||||||||
point in time: 15 July 2021
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Revision as of 12:35, 15 July 2021
Project Q3056450 in Latvia
| Language | Label | Description | Also known as |
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| English | No label defined |
Project Q3056450 in Latvia |
Statements
584,177.01 Euro
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799,801.16 Euro
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1 July 2020
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30 June 2023
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Nodibinājums "VIDES RISINĀJUMU INSTITŪTS"
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56°58'25.43"N, 24°4'37.92"E
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Projekta mērķis ir izstrādāt augstas pievienotās vērtības bioloģiski aktīvu savienojumu, kas potenciāli izmantojams kosmētikā, ar raksturīgu drošuma un iedarbīguma profilu, no ārstniecības augu (Matricaria) pārstrādes un in vitro šūnu (Dracocephalum, Ribes and Juniperus) kultivēšanas blakusproduktiem, izmantojot superkritiskā šķidruma ekstrakcijas un frakcionēšanas modernākās tehnoloģijas. Projektā ir sešas galvenajās darbības:1. Bioloģiski aktīvo savienojumu ekstrahēšana no ārstniecības augu pārstrādes un šūnu in vitro kultivēšanas blakusproduktiem, izmantojot superkritiskā šķidruma ekstrakciju (SFE) ar superkritisko oglekļa dioksīdu, rezultātā iegūstot ekstrakcijas metodoloģiju (ekstrakcijas protokolu).2. Polāro un nepolāro savienojumu frakcionēšana no ārstniecības augu pārstrādes superkritiskā šķidruma ekstraktiem; šūnu audzēšana in vitro, iegūstot frakcionēšanas metodikas prototipu (frakcionēšanas protokolu).3. Ekstrakciju un frakciju ķīmiskais raksturojums, izmantojot bioloģiski aktīvo fitoķīmisko klašu kvalitatīvo un kvantitatīvo skrīningu, kā arī dominējošo bioloģiski aktīvo savienojumu identifikācija, izmantojot saistītās metodes (viens fitoķīmiskā skrīninga protokols, viens bioloģiski aktīvo savienojumu identifikācijas protokols).4. Ārstniecības augu pārstrādes un in vitro augu šūnu kultūrās iegūtu sastāvdaļu ražošanas blakusproduktu ekstraktu un frakciju bioloģiskās aktivitātes raksturojums (citotoksiskuma un fototoksiskuma testēšanas pārskati; antibakteriālas aktivitātes testēšanas pārskati; ādas aizsargaktivitātes testēšanas pārskati 10 ekstraktiem un frakcijām).5. Biorafinēšanas frakciju un ekstraktu (no aktivitātēm WP1 un WP2) kombinēšana, lai iegūtu kombinētas kosmētikas līdzekļu sastāvdaļas ar paaugstinātu bioloģisko aktivitāti (TRL 4 kosmētikas līdzekļa sastāvdaļas prototips).6. Projekta vadība un saziņa koncentrēsies uz efektīvu vadību un uz zināšanu nodošanu gan plašai sabiedrībai, gan zinātniskajai aprindām un speciālistiem. Rezultāti tiks izplatīti, publicējot trīs rakstus brīvpieejas (Open Access) zinātniskajos žurnālos, veicot sešas prezentācijas starptautiskās konferencēs un informējot sabiedrību ar interneta, sociālo plašsaziņas līdzekļu un informatīvu pasākumu palīdzību. Šis ir rūpnieciskās pētniecības projekts, saistīts ar biotehnoloģijas un bioekonomikas saimniecisko darbību un to īsteno starpnozaru konsorcijs:Vides risinājumu institūts (VRI) (galvenais partneris) ir zinātniska institūcija, NVO, ko veido zinātnieku, mākslinieku, inženieru un speciālistu, kas rūpējas par vidi, starptautisks tīkls. Institūtā izveidotas daudznozaru komandas, lai izstrādātu un attīstītu pielāgotus novatoriskus vides risinājumus. Pēdējo gadu laikā, realizējot daudzveidīgus projektus, uzkrātas plašas zināšanas gan par dažādu augu sugu, tostarp ārstniecības augu, gan to saturošo praoduktu, tādu kā ēterisko eļļu, ziedūdeņu un garšaugu izpēti, analīzi un testēšanu, kā arī uz datiem balstītu risinājumu izstrādi dabas resursu novērtēšanai. Institūts ir arī aktīvs Eiropas Ārstniecības augu asocācijas (EUROPAM- European Herb Growers Association) biedrs.• SIA “Field and Forest” (FAF) ir sertificēts bioloģiskās lauksaimniecības uzņēmums. Pašlaik tam pieder 338 ha lauksaimniecības zemes un 644 hektāri meža zemes. Vairāk nekā 80 % no lauksaimniecībā izmantojamās zemes tiek audzēti ārstniecības un aromātiskie augi (ĀAA). Uzņēmums ir viens no lielākajiem bioloģiski sertificētu kumelīšu audzētājiem un ražotājiem Austrumeiropā. Pašlaik FAF rūpnieciskos apjomos izstrādā ĀAA ēterisko eļļu un ziedūdeņu destilācijas metodes, lai paaugstinātu šo produktu pievienoto vērtību. Uzņēmums arī eksperimentālos apjomos ievieš novatorisku sašķidrinātas freona gāzes ekstrakciju (fitosola ekstrakciju) no netradicionāliem aromātiskajiem augiem.• Alternative Plants (AP) pašlaik ir vienīgais uzņēmums Baltijas valstīs, kas bioloģiski aktīvo kosmētisko izejvielu ražošanai izmanto augu šūnu kultivēšanas tehnoloģiju. AP koncentrējas uz ārstniecības augiem, kurus ir grūti audzēt, kuri ir reti sastopami vai apdraudēti. AP ir uzņēmums ar pieredzi augu šūnu kultūru izveidē, veicinot atsevišķu ķīmisku savienojumu ražošanu, izmantojot ķīmiskos un fizikālos ierosinātājus un paplašinot šūnu audzēšanu. Līdz sīm AP ir izstrādātas 8 dažādas šūnu kultūras, divas no tām tiek paplašinātas. No augu šūnu biomasas iegūtas sastāvdaļas tiek raksturotas, un tiek pārbaudīta to bioloģiskā aktivitāte. Pašlaik AP ir radījis trīs dažādus produktus. AP ir plaša pieredze ādu aizsargājošu, pretmikrobu un antioksidatīvu vielu izstrādē.Plānotie projekta rezultāti: Produkts “kosmētikas aktīvā sastāvdaļa” - kompozīcija, kas sastāv no dažādu ekstraktu vai frakciju, kuras iegūtas no blakusproduktiem kombinācijas, (prototips -atbilst TRL4kosmētisko līdzekļu kompozītu sastāvdaļu ar augstu pievienoto vērtību novērtēšana;3.825. FTE darba vietas privātajās organizācijās;€215 624.15 privātais pētniecības un attīstības finansējums;Trīs publi (Latvian)
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The aim of the project is to develop high value-added biologically active compounds, potentially usable in cosmetics, with a characteristic safety and efficacy profile, from the processing of medicinal plants (Matricaria) and by-products of in vitro cell (Dracocephalum, Ribes and Juniperus) cultivation using the most advanced technologies of supercritical fluid extraction and fractionation. The project consists of six key actions:1. Extraction of biologically active compounds from therapeutic plant processing and by-products of in vitro cell culture using supercritical fluid extraction (SFE) with supercritical carbon dioxide resulting in extraction methodology (extraction protocol).2. Fractionation of polar and non-polar compounds from extracts of supercritical fluid from herb processing; In vitro cell cultivation resulting in a fractionation methodology prototype (fractionation protocol).3. Chemical characterisation of extractions and fractions using qualitative and quantitative screening of biologically active phytochemical classes as well as the identification of predominant biologically active compounds using related methods (one phytochemical screening protocol, one identification protocol for biologically active compounds).4. Biological activity of extracts and fractions of by-products from the manufacture of medicinal plants and in vitro plant cell cultures (reports of cytotoxicity and phototoxicity tests; Antimicrobial activity testing reports; Test reports for skin protective activity of 10 extracts and fractions).5. Combination of biorefining fractions and extracts (from activities WP1 and WP2) to obtain combinations of high biological activity ingredients in cosmetic products (the prototype of the ingredient of the cosmetic product of the TRL 4).6. Project management and communication will focus on effective management and knowledge transfer to the general public, to the scientific community and to specialists. The results will be disseminated by publishing three articles in Open Access scientific journals, making six presentations at international conferences and informing the public via the Internet, social media and information activities. This is an industrial research project, related to the economic activities of biotechnology and bioeconomy, and is carried out by a cross-sectoral consortium: Institute for Environmental Solutions (VRI) (the main partner) is a scientific institution, an international network of scientists, artists, engineers and specialists who care for the environment. The Institute has established multidisciplinary teams to develop and develop tailor-made innovative environmental solutions. In recent years extensive knowledge has been gained from various projects on the research, analysis and testing of various plant species, including medicinal plants and their practices, such as essential oils, flower water and herbs, as well as the development of data-based solutions for the assessment of natural resources. The Institute is also an active member of the European Herb Growers Association.• SIA Field and Forest (FAF) is a certified organic farming company. It currently owns 338 ha of agricultural land and 644 hectares of forest land. More than 80 % of agricultural land is cultivated with medicinal and aromatic plants. The company is one of the largest organic camomile growers and producers in Eastern Europe. The FAF currently develops AAA essential oils and flower water distillation methods in industrial volumes in order to increase the added value of these products. The company is also introducing an innovative extraction of liquefied freon gas (phytosol extraction) from unconventional aromatic plants in experimental volumes.• Alternative Plants (AP) is currently the only company in the Baltic States that uses plant cell cultivation technology to produce biologically active cosmetic raw materials. The HR focuses on medicinal plants that are difficult to grow, which are rare or at risk. The AP is a company with experience in the creation of plant cell cultures, promoting the production of certain chemical compounds, using chemical and physical agents and expanding cell cultivation. Up to the sims, the AP has developed 8 different cell cultures, two of which are expanded. Components derived from plant cell biomass are characterised and their biological activity tested. At present, the EaP has created three different products. The AP has extensive experience in the development of anti-microbial and antioxidative substances. Product ‘cosmetic active ingredient’: a composition consisting of a combination of different extracts or fractions of by-products (prototype – corresponding to the evaluation of TRL4 high value added composite components of cosmetic products;3.825. FTE jobs in private organisations; EUR215 624.15 private R & D funding;Three public (English)
15 July 2021
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Lidlauks, Priekuļu pag., Cēsu nov., LV-4126
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Izstādes iela 2, Priekuļi, Priekuļu pag., Cēsu nov., LV-4126
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Podraga iela 2, Rīga, LV-1007
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Identifiers
1.1.1.1/19/A/075
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