Centre of Excellence for Analytical and Diagnostic Research for Health and Sports Performance (Q3923158): Difference between revisions
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The government’s declared goal is to develop sport into a strategic sector, focusing on infrastructure and human resource expansion. The aim of the planned excellence workshop is to improve the latter’s quality, where we will research the methods of legal increase in sport performance, using the most modern fine analytical, blood-biochemical and molecular process analysis toolkit. The Hungarian Olympic Committee, which intends to organise the 2024 Olympics, also encourages the practical use of the results. By expanding the existing equipment pool and the research community at PTE, and with the help of basic scientific and applied research based on the available large sample athletes’ dataset, we will provide useful results for practitioners, which can be realised later in innovative tool developments. Diagnostics and performance enhancements supported by molecular foundations are also sporadically sporadic in Hungary and other major sports powers, taking this into account this proposal is a unique opportunity. In line with the objective of the National Intelligent Specialisation Strategy, the primary and long-term goal of this application is to strengthen the R & D capacity of our existing knowledge bases in order to produce internationally listed, high-quality research results. The Centre of Excellence for the purpose of the application combines the facilities of preventive and curative medical, sport science and performance diagnostics, molecular impact analysis and fine analytics research at our university. We hope that a combination of these would create a multidisciplinary research potential at the international forefront of the field of science. Monitoring of athlete performance based on molecular markers is not a new problem. The success of such attempts and the comparability of the results of the different centres is greatly limited by the differences in sampling and processing protocols and by the fact that the performance diagnostic tests underlying the process are performed under non-standardised conditions. All interventions and tests in the proposed centre of excellence would be carried out under standardised conditions, sampling, processing and storage would be based on optimised protocols. Furthermore, by aligning the perspectives of researchers with very different disciplines in the centre, it is possible to carry out scientifically valuable studies already at the design stage. To our knowledge, the centre of excellence proposed in the application would be the first research organisation with such characteristics in Hungary. In our studies we strive to use non-invasive sampling techniques, or to diagnose and monitor as small as possible. Our project supports the “Sporting Nation” concept, the effective operation of sports academies and clubs. Coordination of basic and applied research would develop research potential and performance in a self-exciting way. Sport science and sport medicine are characterised by the fact that the number of citations per average article in the field’s Q1 journals is in the range 0.8-2.8. Accordingly, research that inspires significant international interest must go beyond standard standards in terms of applied methodology, target group or topic. It must therefore be able to appear not in those specialist journals, but primarily in scientific journals of a broad scientific spectrum, physiological or medical. The proposed Centre of Excellence appears to be suitable in several respects. On the one hand, the processing of samples from tests carried out under standardised conditions with state-of-the-art methods ensures that scientific thoroughness cannot be criticised, and the studies proposed in this application, such as the full and sport-specific assessment of athletes, the determination of load physiological risk rates for free games, the identification of performance-related molecular markers, the separation of genetic potential and Exercise from each other, the issue of over-training or the examination of micro-injuries are among the most researched topics in the field. At the same time, a multidisciplinary approach can make such research suitable for achieving high standards and of interest to the wider scientific public. In the course of our project, we examine the anthropometric, load physiological, biomechanical and molecular parameters of individual and team sports as a function of performance. Our methodological studies can be divided into three groups. 1. Performance Physiology: With proprietary software, we monitor performance indicators using dynamometric, electromyographic, electro- and transcranial magnetic stimulation techniques, in addition to monitoring cardiovascular parameters. 2. Finomaanalysis: Fine-analytical analysis of the blood and saliva samples obtained during the load with HPLC and the mass spectrome of LCMS-Q-tof (English) | |||||||||||||||
| Property / summary: The government’s declared goal is to develop sport into a strategic sector, focusing on infrastructure and human resource expansion. The aim of the planned excellence workshop is to improve the latter’s quality, where we will research the methods of legal increase in sport performance, using the most modern fine analytical, blood-biochemical and molecular process analysis toolkit. The Hungarian Olympic Committee, which intends to organise the 2024 Olympics, also encourages the practical use of the results. By expanding the existing equipment pool and the research community at PTE, and with the help of basic scientific and applied research based on the available large sample athletes’ dataset, we will provide useful results for practitioners, which can be realised later in innovative tool developments. Diagnostics and performance enhancements supported by molecular foundations are also sporadically sporadic in Hungary and other major sports powers, taking this into account this proposal is a unique opportunity. In line with the objective of the National Intelligent Specialisation Strategy, the primary and long-term goal of this application is to strengthen the R & D capacity of our existing knowledge bases in order to produce internationally listed, high-quality research results. The Centre of Excellence for the purpose of the application combines the facilities of preventive and curative medical, sport science and performance diagnostics, molecular impact analysis and fine analytics research at our university. We hope that a combination of these would create a multidisciplinary research potential at the international forefront of the field of science. Monitoring of athlete performance based on molecular markers is not a new problem. The success of such attempts and the comparability of the results of the different centres is greatly limited by the differences in sampling and processing protocols and by the fact that the performance diagnostic tests underlying the process are performed under non-standardised conditions. All interventions and tests in the proposed centre of excellence would be carried out under standardised conditions, sampling, processing and storage would be based on optimised protocols. Furthermore, by aligning the perspectives of researchers with very different disciplines in the centre, it is possible to carry out scientifically valuable studies already at the design stage. To our knowledge, the centre of excellence proposed in the application would be the first research organisation with such characteristics in Hungary. In our studies we strive to use non-invasive sampling techniques, or to diagnose and monitor as small as possible. Our project supports the “Sporting Nation” concept, the effective operation of sports academies and clubs. Coordination of basic and applied research would develop research potential and performance in a self-exciting way. Sport science and sport medicine are characterised by the fact that the number of citations per average article in the field’s Q1 journals is in the range 0.8-2.8. Accordingly, research that inspires significant international interest must go beyond standard standards in terms of applied methodology, target group or topic. It must therefore be able to appear not in those specialist journals, but primarily in scientific journals of a broad scientific spectrum, physiological or medical. The proposed Centre of Excellence appears to be suitable in several respects. On the one hand, the processing of samples from tests carried out under standardised conditions with state-of-the-art methods ensures that scientific thoroughness cannot be criticised, and the studies proposed in this application, such as the full and sport-specific assessment of athletes, the determination of load physiological risk rates for free games, the identification of performance-related molecular markers, the separation of genetic potential and Exercise from each other, the issue of over-training or the examination of micro-injuries are among the most researched topics in the field. At the same time, a multidisciplinary approach can make such research suitable for achieving high standards and of interest to the wider scientific public. In the course of our project, we examine the anthropometric, load physiological, biomechanical and molecular parameters of individual and team sports as a function of performance. Our methodological studies can be divided into three groups. 1. Performance Physiology: With proprietary software, we monitor performance indicators using dynamometric, electromyographic, electro- and transcranial magnetic stimulation techniques, in addition to monitoring cardiovascular parameters. 2. Finomaanalysis: Fine-analytical analysis of the blood and saliva samples obtained during the load with HPLC and the mass spectrome of LCMS-Q-tof (English) / rank | |||||||||||||||
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| Property / summary: The government’s declared goal is to develop sport into a strategic sector, focusing on infrastructure and human resource expansion. The aim of the planned excellence workshop is to improve the latter’s quality, where we will research the methods of legal increase in sport performance, using the most modern fine analytical, blood-biochemical and molecular process analysis toolkit. The Hungarian Olympic Committee, which intends to organise the 2024 Olympics, also encourages the practical use of the results. By expanding the existing equipment pool and the research community at PTE, and with the help of basic scientific and applied research based on the available large sample athletes’ dataset, we will provide useful results for practitioners, which can be realised later in innovative tool developments. Diagnostics and performance enhancements supported by molecular foundations are also sporadically sporadic in Hungary and other major sports powers, taking this into account this proposal is a unique opportunity. In line with the objective of the National Intelligent Specialisation Strategy, the primary and long-term goal of this application is to strengthen the R & D capacity of our existing knowledge bases in order to produce internationally listed, high-quality research results. The Centre of Excellence for the purpose of the application combines the facilities of preventive and curative medical, sport science and performance diagnostics, molecular impact analysis and fine analytics research at our university. We hope that a combination of these would create a multidisciplinary research potential at the international forefront of the field of science. Monitoring of athlete performance based on molecular markers is not a new problem. The success of such attempts and the comparability of the results of the different centres is greatly limited by the differences in sampling and processing protocols and by the fact that the performance diagnostic tests underlying the process are performed under non-standardised conditions. All interventions and tests in the proposed centre of excellence would be carried out under standardised conditions, sampling, processing and storage would be based on optimised protocols. Furthermore, by aligning the perspectives of researchers with very different disciplines in the centre, it is possible to carry out scientifically valuable studies already at the design stage. To our knowledge, the centre of excellence proposed in the application would be the first research organisation with such characteristics in Hungary. In our studies we strive to use non-invasive sampling techniques, or to diagnose and monitor as small as possible. Our project supports the “Sporting Nation” concept, the effective operation of sports academies and clubs. Coordination of basic and applied research would develop research potential and performance in a self-exciting way. Sport science and sport medicine are characterised by the fact that the number of citations per average article in the field’s Q1 journals is in the range 0.8-2.8. Accordingly, research that inspires significant international interest must go beyond standard standards in terms of applied methodology, target group or topic. It must therefore be able to appear not in those specialist journals, but primarily in scientific journals of a broad scientific spectrum, physiological or medical. The proposed Centre of Excellence appears to be suitable in several respects. On the one hand, the processing of samples from tests carried out under standardised conditions with state-of-the-art methods ensures that scientific thoroughness cannot be criticised, and the studies proposed in this application, such as the full and sport-specific assessment of athletes, the determination of load physiological risk rates for free games, the identification of performance-related molecular markers, the separation of genetic potential and Exercise from each other, the issue of over-training or the examination of micro-injuries are among the most researched topics in the field. At the same time, a multidisciplinary approach can make such research suitable for achieving high standards and of interest to the wider scientific public. In the course of our project, we examine the anthropometric, load physiological, biomechanical and molecular parameters of individual and team sports as a function of performance. Our methodological studies can be divided into three groups. 1. Performance Physiology: With proprietary software, we monitor performance indicators using dynamometric, electromyographic, electro- and transcranial magnetic stimulation techniques, in addition to monitoring cardiovascular parameters. 2. Finomaanalysis: Fine-analytical analysis of the blood and saliva samples obtained during the load with HPLC and the mass spectrome of LCMS-Q-tof (English) / qualifier | |||||||||||||||
point in time: 8 February 2022
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Revision as of 17:46, 8 February 2022
Project Q3923158 in Hungary
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | Centre of Excellence for Analytical and Diagnostic Research for Health and Sports Performance |
Project Q3923158 in Hungary |
Statements
1,412,733,061 forint
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3,861,883.262 Euro
0.0027336256 Euro
15 December 2021
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1,412,733,061.0 forint
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100.0 percent
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1 February 2017
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31 October 2021
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PÉCSI TUDOMÁNYEGYETEM
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46°4'35.72"N, 18°13'40.94"E
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A Kormány deklarált célja a sport stratégiai ágazattá fejlesztése, a törekvés fókuszában infrastruktúra és a humán-erőforrás bővítés áll. Az utóbbi minőségi javítását célozza a tervezett kiválósági műhely, ahol a sportteljesítmény legális növelésének módszereit fogjuk kutatni, alkalmazva a legmodernebb finomanalitikai, vér-biokémiai, molekuláris folyamatelemzési eszköztárat. Az eredmények gyakorlati hasznosítását a 2024-es olimpiát megrendezni kívánó Magyar Olimpiai Bizottság is szorgalmazza. A PTE-n meglevő eszközpark és kutatói kör bővítésével, valamint a rendelkezésre álló nagymintás sportolói adatállományra építő tudományos alap- és alkalmazott kutatások segítségével, gyakorló szakemberek számára is hasznosítható eredményeket fogunk közölni, amelyek a későbbiekben innovatív eszközfejlesztésekben is realizálódhatnak. Hazánkban és más sport-nagyhatalmakban is sporadikus még a molekuláris alapokkal támogatott diagnosztika és teljesítményfokozás, ezt figyelembe véve jelen pályázat unikális lehetőség. Jelen pályázatunk, összhangban a Nemzeti Intelligens Szakosodási Stratégia célkitűzésével, elsődleges és hosszútávú célja meglévő tudásbázisaink K+F kapacitásának erősítése annak érdekében, hogy nemzetközileg jegyzett, magas színvonalú kutatási eredmények születhessenek. A pályázat célját képező kiválósági központ egyesíti az egyetemünkön meglévő preventív és kuratív medicinális, a sporttudományi és teljesítménydiagnosztikai, valamint a molekuláris hatások elemzésének és finomanalitikai kutatásainak facilitásait. Ezek együttese reményeink szerint a tudományterület nemzetközi élvonalába tartozó multidiszciplináris kutatási potenciált hozna létre. A sportolói teljesítmény molekuláris markereken alapuló monitorozása nem újkeletű probléma. Az erre irányuló próbálkozások sikerét, és a különböző centrumok eredményeinek összevethetőségét nagyban limitálja a mintavételi és feldolgozási protokollok eltérő volta, valamint az, hogy a folyamat alapjául szolgáló teljesítménydiagnosztikai vizsgálatokat nem standardizált körülmények között hajtják végre. A javasolt kiválósági centrumban az összes beavatkozás és vizsgálat, standardizált körülmények között valósulna meg, a mintavétel, feldolgozás és tárolás optimálizált protokollok szerint történne. Továbbá, a centrumot alkotó nagyon eltérő diszciplináris háttérrel rendelkező kutatók szempontjainak összehangolásával már a tervezés fázisában tudományosan valóban értékes vizsgálatokat lehet elvégezni. Tudomásunk szerint, a pályázatban javasolt kiválósági centrum az első ilyen sajátosságokkal rendelkező kutatóhely lenne Magyarországon. Vizsgálatainkban törekszünk a nem-invazív mintavételi technikák alkalmazására, vagy minél kisebb mintából történő diagnosztizálásra, monitorozása. Projektünk alapjaiban támogatja a „Sportoló Nemzet” koncepciót, a sportakadémiák, a klubok hatékony működését. Az alap- és alkalmazott kutatások összehangolása öngerjesztő módon fejlesztené a kutatási potenciált és teljesítményt. A sporttudomány és sportmedicina jellegzetessége, hogy a terület Q1-es szakfolyóirataiban az átlagos cikkre jutó citációk száma a 0.8-2.8 tartományba esik. Ennek megfelelően a jelentős nemzetközi érdeklődésre aspiráló kutatásoknak az alkalmazott metodikák, a célcsoport vagy a téma tekintetében meg kell haladnia a szokványos színvonalat. Ezáltal alkalmasnak kell lennie arra, hogy nem az említett szakfolyóiratokban, hanem elsősorban széles tudományos spektrumú, élettani vagy orvosi tudományos folyóiratokban tudjon megjelenni. A javasolt kiválósági centrum több szempontból is alkalmasnak látszik erre. Egyrészt a standardizált körülmények között végzett vizsgálatokból származó minták legmodernebb metodikákkal történő feldolgozása biztosíték arra, hogy a tudományos alaposság ne legyen kifogásolható, továbbá, a jelen pályázatban javasolt vizsgálatok, mint amilyen a sportolók teljes körű és sportágspecifikus felmérése, a szabadjátékok terhelésélettani kockázati rátáinak meghatározása, teljesítménnyel összefüggő molekuláris markerek azonosítása, a genetikai potenciál és edzhetőség elválasztása egymástól, a túledzettség kérdése vagy éppen a mikrosérülések vizsgálata a szakterület leginkább kutatott témái közé tartoznak. Ugyanakkor, a multidiszciplináris megközelítés a kiemelkedő színvonal elérésére alkalmassá, és a szélesebb tudományos közvélemény számára érdekessé teheti ezeket a kutatásokat. Projektünk során a és egyéni és csapatsportágakat űzők antropometriai, terhelésélettani, biomechanikai és molekuláris paramétereit vizsgáljuk a teljesítmény függvényében. Módszertani vizsgálataink három csoportba oszthatók. 1. Teljesítményélettan: Saját fejlesztésű szoftverekkel a kardiovaszkuláris paraméterek követése mellett dinamometriai, elektromiográfiai, valamint elektro- és transcraniális mágneses stimulációs technikákkal monitorozzuk a teljesítménymutatókat. 2. Finomanalítika: A terhelés során nyert vér és nyálminták finomanalitikai elemzése HPLC-vel, valamint LCMS-Q-tof tömegspektromét (Hungarian)
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The government’s declared goal is to develop sport into a strategic sector, focusing on infrastructure and human resource expansion. The aim of the planned excellence workshop is to improve the latter’s quality, where we will research the methods of legal increase in sport performance, using the most modern fine analytical, blood-biochemical and molecular process analysis toolkit. The Hungarian Olympic Committee, which intends to organise the 2024 Olympics, also encourages the practical use of the results. By expanding the existing equipment pool and the research community at PTE, and with the help of basic scientific and applied research based on the available large sample athletes’ dataset, we will provide useful results for practitioners, which can be realised later in innovative tool developments. Diagnostics and performance enhancements supported by molecular foundations are also sporadically sporadic in Hungary and other major sports powers, taking this into account this proposal is a unique opportunity. In line with the objective of the National Intelligent Specialisation Strategy, the primary and long-term goal of this application is to strengthen the R & D capacity of our existing knowledge bases in order to produce internationally listed, high-quality research results. The Centre of Excellence for the purpose of the application combines the facilities of preventive and curative medical, sport science and performance diagnostics, molecular impact analysis and fine analytics research at our university. We hope that a combination of these would create a multidisciplinary research potential at the international forefront of the field of science. Monitoring of athlete performance based on molecular markers is not a new problem. The success of such attempts and the comparability of the results of the different centres is greatly limited by the differences in sampling and processing protocols and by the fact that the performance diagnostic tests underlying the process are performed under non-standardised conditions. All interventions and tests in the proposed centre of excellence would be carried out under standardised conditions, sampling, processing and storage would be based on optimised protocols. Furthermore, by aligning the perspectives of researchers with very different disciplines in the centre, it is possible to carry out scientifically valuable studies already at the design stage. To our knowledge, the centre of excellence proposed in the application would be the first research organisation with such characteristics in Hungary. In our studies we strive to use non-invasive sampling techniques, or to diagnose and monitor as small as possible. Our project supports the “Sporting Nation” concept, the effective operation of sports academies and clubs. Coordination of basic and applied research would develop research potential and performance in a self-exciting way. Sport science and sport medicine are characterised by the fact that the number of citations per average article in the field’s Q1 journals is in the range 0.8-2.8. Accordingly, research that inspires significant international interest must go beyond standard standards in terms of applied methodology, target group or topic. It must therefore be able to appear not in those specialist journals, but primarily in scientific journals of a broad scientific spectrum, physiological or medical. The proposed Centre of Excellence appears to be suitable in several respects. On the one hand, the processing of samples from tests carried out under standardised conditions with state-of-the-art methods ensures that scientific thoroughness cannot be criticised, and the studies proposed in this application, such as the full and sport-specific assessment of athletes, the determination of load physiological risk rates for free games, the identification of performance-related molecular markers, the separation of genetic potential and Exercise from each other, the issue of over-training or the examination of micro-injuries are among the most researched topics in the field. At the same time, a multidisciplinary approach can make such research suitable for achieving high standards and of interest to the wider scientific public. In the course of our project, we examine the anthropometric, load physiological, biomechanical and molecular parameters of individual and team sports as a function of performance. Our methodological studies can be divided into three groups. 1. Performance Physiology: With proprietary software, we monitor performance indicators using dynamometric, electromyographic, electro- and transcranial magnetic stimulation techniques, in addition to monitoring cardiovascular parameters. 2. Finomaanalysis: Fine-analytical analysis of the blood and saliva samples obtained during the load with HPLC and the mass spectrome of LCMS-Q-tof (English)
8 February 2022
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Pécs, Baranya
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Identifiers
GINOP-2.3.2-15-2016-00047
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