(3553.04032020.158000265) SOFIA (Q4081996): Difference between revisions
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(Changed label, description and/or aliases in en: Setting new description) |
(Changed label, description and/or aliases in en, and other parts: Adding English translations) |
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(3553.04032020.158000265) SOFIA | |||||||||||||||
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AT PRESENT, BIOLOGICAL, COSMETIC AND PHARMACEUTICAL RESEARCH USES ANIMAL TESTING AS A STANDARD METHOD, BUT A LARGE PART OF THE RESULTS OBTAINED ARE DIFFICULT TO TRANSFER TO HUMANS; IN FACT, THE CASES OF FAILURE OF ACTIVE AGENTS TESTED IN THIS WAY AND STARTED AT THE NEXT CLINICAL STAGES ARE AROUND 90 %.OTHER THESE TESTS ARE EXPENSIVE: TO THE COST OF THE GUINEA PIGS SHOULD IN FACT BE ADDED THE AMORTISATION OF THE ENCLOSURE, OF THE NECESSARY TO KEEP THE STRUCTURE FUNCTIONING, AS WELL AS TO THE NECESSARY CARE DURING THE GROWTH AND MATURATION OF THE GUINEA PIG UNTIL IT IS PREPARED FOR THE TEST.L? ALTERNATIVE TO ANIMAL TESTING? REPRESENTED BY IN-VITRO MODELS, I.E. CELL CULTURES OR EXPLANTS OF TISSUES GROWN IN AN ARTIFICIAL AND CONTROLLED ENVIRONMENT, WHICH ALLOW A SIMPLE AND EXTENSIVE FIRST SCREENING OF THE SUBSTANCES TO BE TESTED. UNFORTUNATELY, COMMONLY ACCEPTED IN-VITRO MODELS USE OUTDATED TECHNOLOGIES AND ALLOW ONLY STRONG APPROXIMATIONS (English) | |||||||||||||||
| Property / summary: AT PRESENT, BIOLOGICAL, COSMETIC AND PHARMACEUTICAL RESEARCH USES ANIMAL TESTING AS A STANDARD METHOD, BUT A LARGE PART OF THE RESULTS OBTAINED ARE DIFFICULT TO TRANSFER TO HUMANS; IN FACT, THE CASES OF FAILURE OF ACTIVE AGENTS TESTED IN THIS WAY AND STARTED AT THE NEXT CLINICAL STAGES ARE AROUND 90 %.OTHER THESE TESTS ARE EXPENSIVE: TO THE COST OF THE GUINEA PIGS SHOULD IN FACT BE ADDED THE AMORTISATION OF THE ENCLOSURE, OF THE NECESSARY TO KEEP THE STRUCTURE FUNCTIONING, AS WELL AS TO THE NECESSARY CARE DURING THE GROWTH AND MATURATION OF THE GUINEA PIG UNTIL IT IS PREPARED FOR THE TEST.L? ALTERNATIVE TO ANIMAL TESTING? REPRESENTED BY IN-VITRO MODELS, I.E. CELL CULTURES OR EXPLANTS OF TISSUES GROWN IN AN ARTIFICIAL AND CONTROLLED ENVIRONMENT, WHICH ALLOW A SIMPLE AND EXTENSIVE FIRST SCREENING OF THE SUBSTANCES TO BE TESTED. UNFORTUNATELY, COMMONLY ACCEPTED IN-VITRO MODELS USE OUTDATED TECHNOLOGIES AND ALLOW ONLY STRONG APPROXIMATIONS (English) / rank | |||||||||||||||
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| Property / summary: AT PRESENT, BIOLOGICAL, COSMETIC AND PHARMACEUTICAL RESEARCH USES ANIMAL TESTING AS A STANDARD METHOD, BUT A LARGE PART OF THE RESULTS OBTAINED ARE DIFFICULT TO TRANSFER TO HUMANS; IN FACT, THE CASES OF FAILURE OF ACTIVE AGENTS TESTED IN THIS WAY AND STARTED AT THE NEXT CLINICAL STAGES ARE AROUND 90 %.OTHER THESE TESTS ARE EXPENSIVE: TO THE COST OF THE GUINEA PIGS SHOULD IN FACT BE ADDED THE AMORTISATION OF THE ENCLOSURE, OF THE NECESSARY TO KEEP THE STRUCTURE FUNCTIONING, AS WELL AS TO THE NECESSARY CARE DURING THE GROWTH AND MATURATION OF THE GUINEA PIG UNTIL IT IS PREPARED FOR THE TEST.L? ALTERNATIVE TO ANIMAL TESTING? REPRESENTED BY IN-VITRO MODELS, I.E. CELL CULTURES OR EXPLANTS OF TISSUES GROWN IN AN ARTIFICIAL AND CONTROLLED ENVIRONMENT, WHICH ALLOW A SIMPLE AND EXTENSIVE FIRST SCREENING OF THE SUBSTANCES TO BE TESTED. UNFORTUNATELY, COMMONLY ACCEPTED IN-VITRO MODELS USE OUTDATED TECHNOLOGIES AND ALLOW ONLY STRONG APPROXIMATIONS (English) / qualifier | |||||||||||||||
point in time: 27 January 2022
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Revision as of 10:20, 27 January 2022
Project Q4081996 in Italy
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | (3553.04032020.158000265) SOFIA |
Project Q4081996 in Italy |
Statements
33,821.91 Euro
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67,643.82 Euro
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50.0 percent
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IVTECH SRL
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ATTUALMENTE LA RICERCA NEL CAMPO BIOLOGICO, COSMETICO E FARMACEUTICO UTILIZZA I TEST SU ANIMALI COME METODO STANDARD, MA UNA LARGA PARTE DEI RISULTATI OTTENUTI SONO DIFFICILMENTE TRASFERIBILI SULL?UOMO; INFATTI I CASI DI FALLIMENTO DI AGENTI ATTIVI TESTATI IN QUESTO MODO E AVVIATI ALLE SUCCESSIVE FASI CLINICHE SI AGGIRANO INTORNO AL 90%.INOLTRE QUESTI TEST SONO COSTOSI: AL COSTO DELLE CAVIE VA INFATTI AGGIUNTO L?AMMORTAMENTO DELLO STABULARIO, DEL NECESSARIO PER MANTENERE LA STRUTTURA FUNZIONANTE, OLTRE CHE ALLE CURE NECESSARIE DURANTE LA CRESCITA E MATURAZIONE DELLA CAVIA FINO A PREPARARLA PER IL TEST.L?ALTERNATIVA AI TEST ANIMALI ? RAPPRESENTATA DAI MODELLI IN-VITRO, OVVERO COLTURE CELLULARI O ESPIANTI DI TESSUTI FATTI CRESCERE IN UN AMBIENTE ARTIFICIALE E CONTROLLATO, CHE CONSENTONO UN PRIMO SCREENING SEMPLICE ED ESTENSIVO DELLE SOSTANZE DA TESTARE. SFORTUNATAMENTE, I MODELLI IN-VITRO AD OGGI COMUNEMENTE ACCETTATI UTILIZZANO TECNOLOGIE OBSOLETE E CONSENTONO SOLO FORTI APPROSSIMAZIONI (Italian)
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AT PRESENT, BIOLOGICAL, COSMETIC AND PHARMACEUTICAL RESEARCH USES ANIMAL TESTING AS A STANDARD METHOD, BUT A LARGE PART OF THE RESULTS OBTAINED ARE DIFFICULT TO TRANSFER TO HUMANS; IN FACT, THE CASES OF FAILURE OF ACTIVE AGENTS TESTED IN THIS WAY AND STARTED AT THE NEXT CLINICAL STAGES ARE AROUND 90 %.OTHER THESE TESTS ARE EXPENSIVE: TO THE COST OF THE GUINEA PIGS SHOULD IN FACT BE ADDED THE AMORTISATION OF THE ENCLOSURE, OF THE NECESSARY TO KEEP THE STRUCTURE FUNCTIONING, AS WELL AS TO THE NECESSARY CARE DURING THE GROWTH AND MATURATION OF THE GUINEA PIG UNTIL IT IS PREPARED FOR THE TEST.L? ALTERNATIVE TO ANIMAL TESTING? REPRESENTED BY IN-VITRO MODELS, I.E. CELL CULTURES OR EXPLANTS OF TISSUES GROWN IN AN ARTIFICIAL AND CONTROLLED ENVIRONMENT, WHICH ALLOW A SIMPLE AND EXTENSIVE FIRST SCREENING OF THE SUBSTANCES TO BE TESTED. UNFORTUNATELY, COMMONLY ACCEPTED IN-VITRO MODELS USE OUTDATED TECHNOLOGIES AND ALLOW ONLY STRONG APPROXIMATIONS (English)
27 January 2022
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PISA
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