ROGOWSKI (Q3680495): Difference between revisions
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(Created claim: summary (P836): Neurodegenerative pathologies lead to progressive deterioration of nerve cells causing symptoms of dementia. There is currently no treatment available to cure or limit the evolution of this dementia. The ROGOWSKI project pursues the objective of developing molecular compounds targeting an enzyme expressed in neurons and whose function is critical for the regulation of microtubules structuring cells. Research on this enzyme should ultimately lim...) |
(Changed label, description and/or aliases in en: translated_label) |
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Revision as of 17:09, 18 November 2021
Project Q3680495 in France
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | ROGOWSKI |
Project Q3680495 in France |
Statements
84,306.4 Euro
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297,688.0 Euro
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28.32 percent
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16 August 2017
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15 August 2019
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SATT AxLR SAS
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Les pathologies neurodégénératives entraînent une détérioriation progressive des cellules nerveuses provoquant des symptômes de démence. Il n'existe aujourd'hui aucun traitement permettant de guérir cette démence ou d'en limiter l'évolution. Le projet ROGOWSKI poursuit l'objectif de développement de composés moléculaires ciblant une enzyme exprimée dans les neurones et dont la fonction est critique pour la régulation des microtubules structurant les cellules. Les recherches menées sur cette enzyme doivent permettre à terme de limiter le changement morphologique des cellules et leur détérioration, en identifiant de nouvelles thérapies susceptibles de faire usage d'inhibiteurs de cette enzyme. (French)
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Neurodegenerative pathologies lead to progressive deterioration of nerve cells causing symptoms of dementia. There is currently no treatment available to cure or limit the evolution of this dementia. The ROGOWSKI project pursues the objective of developing molecular compounds targeting an enzyme expressed in neurons and whose function is critical for the regulation of microtubules structuring cells. Research on this enzyme should ultimately limit the morphological change of cells and their deterioration by identifying new therapies that may use inhibitors of this enzyme. (English)
18 November 2021
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Identifiers
LR0015473
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