Q3699866 (Q3699866): Difference between revisions
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(Created claim: summary (P836): MenisCare aims to propose a new approach to knee menisc surgery, by promoting the repair of meniscale lesions rather than ablation (meniscectomy). Preserving meniscus means preventing knee degradation, and delaying the ultimate treatment of osteoarthritis for as long as possible: the total knee prosthesis. At present, the literature shows a failure rate of meniscale repair between 5 % and 43 %. One of the main criteria for establishing a prognos...) |
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MenisCare aims to propose a new approach to knee menisc surgery, by promoting the repair of meniscale lesions rather than ablation (meniscectomy). Preserving meniscus means preventing knee degradation, and delaying the ultimate treatment of osteoarthritis for as long as possible: the total knee prosthesis. At present, the literature shows a failure rate of meniscale repair between 5 % and 43 %. One of the main criteria for establishing a prognosis of success is the presence of blood capillaries (microvascularisation) in the injured area to be sutured. This microvascularisation is currently not detectable under operating conditions, nor in pre-operative imaging. As lesions are in more than 50 % of the cases in the uncertainty zone, the surgeon’s decision tends in the overwhelming majority of cases to ablation rather than to an uncertain outcome repair. The challenge of the project is to provide the surgeon with repair options in all clinical cases: — an in-operative imaging tool to determine, with a sufficient level of certainty, whether a suture can be successfully carried out. — a new therapy for menisk for unsuturable lesions. This project has a major public health issue on the prevention of osteoarthritis, on reducing the loss of mobility, activity and autonomy. (English) | |||||||||||||||
| Property / summary: MenisCare aims to propose a new approach to knee menisc surgery, by promoting the repair of meniscale lesions rather than ablation (meniscectomy). Preserving meniscus means preventing knee degradation, and delaying the ultimate treatment of osteoarthritis for as long as possible: the total knee prosthesis. At present, the literature shows a failure rate of meniscale repair between 5 % and 43 %. One of the main criteria for establishing a prognosis of success is the presence of blood capillaries (microvascularisation) in the injured area to be sutured. This microvascularisation is currently not detectable under operating conditions, nor in pre-operative imaging. As lesions are in more than 50 % of the cases in the uncertainty zone, the surgeon’s decision tends in the overwhelming majority of cases to ablation rather than to an uncertain outcome repair. The challenge of the project is to provide the surgeon with repair options in all clinical cases: — an in-operative imaging tool to determine, with a sufficient level of certainty, whether a suture can be successfully carried out. — a new therapy for menisk for unsuturable lesions. This project has a major public health issue on the prevention of osteoarthritis, on reducing the loss of mobility, activity and autonomy. (English) / rank | |||||||||||||||
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| Property / summary: MenisCare aims to propose a new approach to knee menisc surgery, by promoting the repair of meniscale lesions rather than ablation (meniscectomy). Preserving meniscus means preventing knee degradation, and delaying the ultimate treatment of osteoarthritis for as long as possible: the total knee prosthesis. At present, the literature shows a failure rate of meniscale repair between 5 % and 43 %. One of the main criteria for establishing a prognosis of success is the presence of blood capillaries (microvascularisation) in the injured area to be sutured. This microvascularisation is currently not detectable under operating conditions, nor in pre-operative imaging. As lesions are in more than 50 % of the cases in the uncertainty zone, the surgeon’s decision tends in the overwhelming majority of cases to ablation rather than to an uncertain outcome repair. The challenge of the project is to provide the surgeon with repair options in all clinical cases: — an in-operative imaging tool to determine, with a sufficient level of certainty, whether a suture can be successfully carried out. — a new therapy for menisk for unsuturable lesions. This project has a major public health issue on the prevention of osteoarthritis, on reducing the loss of mobility, activity and autonomy. (English) / qualifier | |||||||||||||||
point in time: 22 November 2021
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Revision as of 11:43, 22 November 2021
Project Q3699866 in France
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | No label defined |
Project Q3699866 in France |
Statements
97,571.0 Euro
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97,571.0 Euro
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100.0 percent
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1 January 2019
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30 June 2023
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UNIVERSITE CLAUDE BERNARD LYON 1
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45°46'57.32"N, 4°52'35.80"E
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69621
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MenisCare vise à proposer une nouvelle approche de la chirurgie du ménisque du genou, en favorisant la réparation des lésions méniscales plutôt que l'ablation (méniscectomie). Préserver le ménisque, c'est prévenir la dégradation du genou, et retarder le plus longtemps possible le traitement ultime de l'arthrose : la prothèse totale de genou. À l'heure actuelle, la littérature montre un taux d'échec de la réparation méniscale entre 5% et 43%. Un des critères majeurs pour l'établissement d'un pronostic de succès est la présence de capillaires sanguines (micro-vascularisation) dans la zone lésée à suturer. Cette micro-vascularisation n'est à l'heure actuelle pas détectable en conditions opératoires, ni en imagerie pré-opératoire. Les lésions étant dans plus de 50% des cas situées dans la zone d'incertitude, la décision du chirurgien penche dans l'écrasante majorité des cas vers une ablation plutôt que vers une réparation à l'issue incertaine. L'enjeu du projet est d'apporter au chirurgien des options de réparation dans tous les cas cliniques : - un outil d'imagerie per-opératoire lui permettant de déterminer, avec un niveau de certitude suffisant, si une suture peut être réalisée avec succès. - une nouvelle thérapie du ménisque pour les lésions non suturables. Ce projet a un enjeu majeur de santé publique sur la prévention de l'arthrose, sur la réduction des pertes de mobilité, d'activité et d'autonomie. (French)
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MenisCare aims to propose a new approach to knee menisc surgery, by promoting the repair of meniscale lesions rather than ablation (meniscectomy). Preserving meniscus means preventing knee degradation, and delaying the ultimate treatment of osteoarthritis for as long as possible: the total knee prosthesis. At present, the literature shows a failure rate of meniscale repair between 5 % and 43 %. One of the main criteria for establishing a prognosis of success is the presence of blood capillaries (microvascularisation) in the injured area to be sutured. This microvascularisation is currently not detectable under operating conditions, nor in pre-operative imaging. As lesions are in more than 50 % of the cases in the uncertainty zone, the surgeon’s decision tends in the overwhelming majority of cases to ablation rather than to an uncertain outcome repair. The challenge of the project is to provide the surgeon with repair options in all clinical cases: — an in-operative imaging tool to determine, with a sufficient level of certainty, whether a suture can be successfully carried out. — a new therapy for menisk for unsuturable lesions. This project has a major public health issue on the prevention of osteoarthritis, on reducing the loss of mobility, activity and autonomy. (English)
22 November 2021
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Identifiers
RA0018296
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