Q3681435 (Q3681435): Difference between revisions
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(Changed label, description and/or aliases in en: Setting new description) |
(Created claim: summary (P836): The social and economic consequences of changes in the nervous system, both during development and during ageing, are considerable. Due to the unprecedented increase in life expectancy of individuals in industrialised countries, the incidence of neurodegenerative diseases and strokes is increasing with great concern. As a result, developing regenerative strategies for the repair of the nervous system and functional recovery has become a major ch...) |
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The social and economic consequences of changes in the nervous system, both during development and during ageing, are considerable. Due to the unprecedented increase in life expectancy of individuals in industrialised countries, the incidence of neurodegenerative diseases and strokes is increasing with great concern. As a result, developing regenerative strategies for the repair of the nervous system and functional recovery has become a major challenge for the coming decades and is the priority research axis of many teams at the Universities of Caen and Rouen. Thus, within our region, there are a large number of teams that develop pharmacological strategies (peptides, non-peptide analogues, extracellular matrix molecules), cell therapies and new medical intervention techniques such as repetitive magnetic stimulation or physical activity to limit neuronal degeneration, promote tissue regeneration and promote functional recovery from nerve system damage caused by cerebral ischemia, subarachnoid hemorrhage, nervous trauma or neurodegenerative disease such as multiple sclerosis. Nevertheless, while the teams involved in this project are working on very complementary issues that often involve methodological developments and similar tools, collaborations in particular with regard to joint publications remain limited. As a result, the 9 research teams and 3 IBiSA platforms participating in this project decided to combine their skills and pool the tools they developed to study the ability of their respective therapeutic strategies to limit neuronal degeneration, promote tissue regeneration and promote functional recovery in the various models of alteration of the central and peripheral nervous system. (English) | |||||||||||||||
| Property / summary: The social and economic consequences of changes in the nervous system, both during development and during ageing, are considerable. Due to the unprecedented increase in life expectancy of individuals in industrialised countries, the incidence of neurodegenerative diseases and strokes is increasing with great concern. As a result, developing regenerative strategies for the repair of the nervous system and functional recovery has become a major challenge for the coming decades and is the priority research axis of many teams at the Universities of Caen and Rouen. Thus, within our region, there are a large number of teams that develop pharmacological strategies (peptides, non-peptide analogues, extracellular matrix molecules), cell therapies and new medical intervention techniques such as repetitive magnetic stimulation or physical activity to limit neuronal degeneration, promote tissue regeneration and promote functional recovery from nerve system damage caused by cerebral ischemia, subarachnoid hemorrhage, nervous trauma or neurodegenerative disease such as multiple sclerosis. Nevertheless, while the teams involved in this project are working on very complementary issues that often involve methodological developments and similar tools, collaborations in particular with regard to joint publications remain limited. As a result, the 9 research teams and 3 IBiSA platforms participating in this project decided to combine their skills and pool the tools they developed to study the ability of their respective therapeutic strategies to limit neuronal degeneration, promote tissue regeneration and promote functional recovery in the various models of alteration of the central and peripheral nervous system. (English) / rank | |||||||||||||||
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| Property / summary: The social and economic consequences of changes in the nervous system, both during development and during ageing, are considerable. Due to the unprecedented increase in life expectancy of individuals in industrialised countries, the incidence of neurodegenerative diseases and strokes is increasing with great concern. As a result, developing regenerative strategies for the repair of the nervous system and functional recovery has become a major challenge for the coming decades and is the priority research axis of many teams at the Universities of Caen and Rouen. Thus, within our region, there are a large number of teams that develop pharmacological strategies (peptides, non-peptide analogues, extracellular matrix molecules), cell therapies and new medical intervention techniques such as repetitive magnetic stimulation or physical activity to limit neuronal degeneration, promote tissue regeneration and promote functional recovery from nerve system damage caused by cerebral ischemia, subarachnoid hemorrhage, nervous trauma or neurodegenerative disease such as multiple sclerosis. Nevertheless, while the teams involved in this project are working on very complementary issues that often involve methodological developments and similar tools, collaborations in particular with regard to joint publications remain limited. As a result, the 9 research teams and 3 IBiSA platforms participating in this project decided to combine their skills and pool the tools they developed to study the ability of their respective therapeutic strategies to limit neuronal degeneration, promote tissue regeneration and promote functional recovery in the various models of alteration of the central and peripheral nervous system. (English) / qualifier | |||||||||||||||
point in time: 18 November 2021
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Revision as of 16:54, 18 November 2021
Project Q3681435 in France
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | No label defined |
Project Q3681435 in France |
Statements
251,500.00 Euro
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503,000.0 Euro
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50.0 percent
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30 September 2021
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UNIVERSITE DE ROUEN-NORMANDIE
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76821
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Les conséquences sociales et économiques des altérations du système nerveux, à la fois pendant le développement mais aussi au cours du vieillissement, sont considérables. En raison de l'accroissement sans précédent de l'espérance de vie des individus dans les pays industrialisés, l'incidence des maladies neurodégénératives et des accidents vasculaires cérébraux augmente de façon très préoccupante. De ce fait, développer des stratégies régénératrices pour la réparation du système nerveux et la récupération fonctionnelle est devenu un défi majeur pour les décennies à venir et constitue l'axe de recherche prioritaire de nombreuses équipes des Universités de Caen et de Rouen. C'est ainsi que l'on retrouve au sein de notre région un nombre important d'équipes qui développent des stratégies pharmacologiques (peptides, analogues non-peptidiques, molécules de la matrice extracellulaire,), des thérapies cellulaires et des nouvelles techniques d'intervention médicale telles que la stimulation magnétique répétitive ou encore la pratique d'une activité physique pour limiter la dégénérescence neuronale, favoriser la régénération tissulaire et promouvoir la récupération fonctionnelle suite à des lésions du système nerveux provoquées par une ischémie cérébrale, une hémorragie sous-arachnoïdienne, un trauma nerveux ou une maladie neurodégénérative comme la sclérose en plaques. Néanmoins, on constate que si les équipes associées à ce projet travaillent sur des problématiques très complémentaires qui font souvent appel à des développements méthodologiques et des outils similaires, les collaborations au regard en particulier des publications conjointes restent limitées. De ce fait, les 9 équipes de recherche et 3 plateformes IBiSA participant à ce projet ont décidé d'associer leurs compétences et de mutualiser les outils qu'elles ont développés pour étudier la capacité de leurs stratégies thérapeutiques respectives à limiter la dégénérescence neuronale, favoriser la régénération tissulaire et promouvoir la récupération fonctionnelle dans les différents modèles d'altération du système nerveux central et périphérique. (French)
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The social and economic consequences of changes in the nervous system, both during development and during ageing, are considerable. Due to the unprecedented increase in life expectancy of individuals in industrialised countries, the incidence of neurodegenerative diseases and strokes is increasing with great concern. As a result, developing regenerative strategies for the repair of the nervous system and functional recovery has become a major challenge for the coming decades and is the priority research axis of many teams at the Universities of Caen and Rouen. Thus, within our region, there are a large number of teams that develop pharmacological strategies (peptides, non-peptide analogues, extracellular matrix molecules), cell therapies and new medical intervention techniques such as repetitive magnetic stimulation or physical activity to limit neuronal degeneration, promote tissue regeneration and promote functional recovery from nerve system damage caused by cerebral ischemia, subarachnoid hemorrhage, nervous trauma or neurodegenerative disease such as multiple sclerosis. Nevertheless, while the teams involved in this project are working on very complementary issues that often involve methodological developments and similar tools, collaborations in particular with regard to joint publications remain limited. As a result, the 9 research teams and 3 IBiSA platforms participating in this project decided to combine their skills and pool the tools they developed to study the ability of their respective therapeutic strategies to limit neuronal degeneration, promote tissue regeneration and promote functional recovery in the various models of alteration of the central and peripheral nervous system. (English)
18 November 2021
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Identifiers
18P03681
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