VALIDATION OF CENTRAL VERSUS PERIPHERY INDICATORS OF STRESS RESPONSE IN FISH (Q3168060): Difference between revisions
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(Created claim: summary (P836): THE COORDINATED DETECSTRESS-2 PROJECT IS DESIGNED TO ANSWER THE QUESTION THAT QUANTIFIABLE AND NON-INVASIVE STRESS INDICATORS CAN BE APPLIED IN AQUACULTURE. IN THIS WAY, THE GENERAL OBJECTIVE OF THIS RESEARCH PROJECT IS TO IMPROVE THE PROCESSES OF ACUICOLA MANAGEMENT IN FISH STRESS EPISODES BY IDENTIFYING AN APPROPRIATE OBJECTIVE FOR THE PROGRAM CHALLENGES, AND USING AS MODEL THE GOLDEN (SPARUS AURATA), MARINE TELEOSTEO OF HIGH COMMERCIAL VALUE....) |
(Changed label, description and/or aliases in en: translated_label) |
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VALIDATION OF CENTRAL VERSUS PERIPHERY INDICATORS OF STRESS RESPONSE IN FISH | |||
Revision as of 16:52, 12 October 2021
Project Q3168060 in Spain
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | VALIDATION OF CENTRAL VERSUS PERIPHERY INDICATORS OF STRESS RESPONSE IN FISH |
Project Q3168060 in Spain |
Statements
111,320.0 Euro
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139,150.0 Euro
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80.0 percent
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30 December 2016
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31 December 2020
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UNIVERSIDAD DE CADIZ
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36°31'43.28"N, 6°11'24.79"W
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11028
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EL PROYECTO COORDINADO DETECSTRESS-2 ESTA DISEÑADO PARA RESPONDER A LA PREGUNTA DE QUE INDICADORES DE ESTRES CUANTIFICABLES Y POCO INVASIVOS SE PUEDEN APLICAR EN ACUICULTURA. DE ESTE MODO, EL OBJETIVO GENERAL DEL PRESENTE PROYECTO DE INVESTIGACION ES MEJORAR LOS PROCESOS DE GESTION ACUICOLA EN LOS EPISODIOS DE ESTRES EN PECES IDENTIFICANDO UN OBJETIVO ADECUADO AL PROGRAMA RETOS, Y UTILIZANDO COMO MODELO LA DORADA (SPARUS AURATA), TELEOSTEO MARINO DE ALTO VALOR COMERCIAL. _x000D_ EN EL PROYECTO SE PROPONE: I) ANALIZAR NUEVOS INDICADORES FISIOLOGICOS Y MOLECULARES DE LA RESPUESTA CENTRAL O SISTEMICA DE LOS PECES AL ESTRES, II) DETERMINAR LA CAPACIDAD DE LOS MARCADORES PERIFERICOS DE LA MUCOSA DE LA PIEL PARA DETECTAR RESPUESTA DE ESTRES, III) COMPLETAR LA CARACTERIZACION DE COMPONENTES DE EJE HIPOTALAMO-HIPOFISARIO-INTERRENAL, Y IV) FINALMENTE VALIDAR LOS INDICADORES NO-INVASIVOS COMPARANDO SU RESPUESTA CON LOS INDICADORES CENTRALES CONOCIDOS (OBJETIVOS ESPECIFICOS 1 AL 4). _x000D_ PARA ELLO ABORDAREMOS EL ANALISIS DE LOS EFECTOS DE DIVERSOS AGENTES ESTRESANTES TIPICOS DE LA PRACTICA ACUICOLA. ASI, SE PROYECTAN UNA SERIE DE 5 EXPERIMENTOS-MODELO CON AGENTES ESTRESANTES DE DIVERSO TIPO. EN PRIMER LUGAR SE ABORDARAN DOS SITUACIONES EXPERIMENTALES DE INTERES PARA LA PRACTICA ACUICOLA QUE CONSTITUYEN DOS DE LOS OBJETIVOS ESPECIFICOS DEL MISMO: I) ESTRES CRONICO POR DENSIDAD CON SUSTANCIAS QUE ATENUEN LA ACTIVACION DEL EJE HIPOTALAMO-HIPOFISARIO-INTERRENAL (OBJETIVO ESPECIFICO 5), Y II) ESTRES INDUCIDO POR TRANSPORTE Y USO DE ANESTESICOS BAJO DOSIS DE SEDACION (OBJETIVO ESPECIFICO 6). DE ACUERDO CON EL PARADIGMA CLASICO, EL ORDEN DE ACTIVACION DEL SISTEMA DE ESTRES TENDRIA UNA DIRECCION DESDE EL CENTRO (HIPOTALAMO) HACIA LA PERIFERIA. SIN EMBARGO, LA INDUCCION NO NECESARIAMENTE SE PRODUCE EN ESTE ORDEN, SINO QUE PUEDE INICIARSE EN LA PERIFERIA. POR ESTE MOTIVO EL PROYECTO INCORPORA TRES DISEÑOS EXPERIMENTALES MAS QUE CONTEMPLAN ESAS NUEVA APROXIMACION: I) EL TRATAMIENTO CON AFLATOXINAS, SUSTANCIAS TOXICAS PRESENTES EN PIENSOS QUE ACTUAN A NIVEL INTESTINAL (OBJETIVO ESPECIFICO 7), II) EL TRATAMIENTO CON NANOPARTICULAS, CONTAMINANTES EMERGENTES PRESENTES EN EL AGUA (OBJETIVO ESPECIFICO 8), Y II) EL TRATAMIENTO CON VACUNA, COMO UN CLASICO ELEMENTO INMUNOGENICO (OBJETIVO ESPECIFICO 9). _x000D_ EN TODOS ESTOS EXPERIMENTOS SE DETERMINARA Y DESPUES SE COMPARARA LA RESPUESTA CENTRAL Y PERIFERICA DE ESTRES, DE UNA MANERA MAS COMPLEJA E INTEGRADA DE LO QUE SE HA ESTADO HACIENDO HASTA EL PRESENTE. FINALMENTE, AL VALIDAR LA RESPUESTA CENTRAL VERSUS PERIFERICA, EL PROYECTO PRETENDE PRESENTAR A LA INDUSTRIA ACUICOLA AQUELLOS INDICADORES DE ESTRES QUE SEAN MAS REPRESENTATIVOS Y QUE PUEDAN SER UTILIZADOS EN LA FORMA MENOS INVASIVA POSIBLE. DE ESTE MODO, LOS RESULTADOS PODRAN SER USADOS PARA UNA OPTIMIZACION DEL CULTIVO DE S. AURATA EN RELACION A LOS EPISODIOS DE ESTRES. LOS RESULTADOS SERAN DIFUNDIDOS TANTO MEDIANTE LA PUBLICACION CIENTIFICA COMO POR INFORMES TECNICOS PARA EL SECTOR._x000D_ EN ESTE PROYECTO SE REUNEN DOS EQUIPOS DE CADIZ Y BARCELONA QUE REUNEN DOS CARACTERISTICAS IMPORTANTES: I) LA EXPERIENCIA EN EL CAMPO DE LA FISIOLOGIA DEL ESTRES EN PECES, Y II) LA CAPACIDAD DE TRABAJAR EN EQUIPO Y EN COLABORACION, COMO HAN DEMOSTRADO ANTERIORMENTE. (Spanish)
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THE COORDINATED DETECSTRESS-2 PROJECT IS DESIGNED TO ANSWER THE QUESTION THAT QUANTIFIABLE AND NON-INVASIVE STRESS INDICATORS CAN BE APPLIED IN AQUACULTURE. IN THIS WAY, THE GENERAL OBJECTIVE OF THIS RESEARCH PROJECT IS TO IMPROVE THE PROCESSES OF ACUICOLA MANAGEMENT IN FISH STRESS EPISODES BY IDENTIFYING AN APPROPRIATE OBJECTIVE FOR THE PROGRAM CHALLENGES, AND USING AS MODEL THE GOLDEN (SPARUS AURATA), MARINE TELEOSTEO OF HIGH COMMERCIAL VALUE. _x000D_ in THE PROJECT IS PROPONE: I) ANALYSE NEW PHYSIOLOGICAL AND MOLECULAR INDICATORS OF THE CENTRAL OR SEISMIC RESPONSE OF FISH TO STRESS, II) DETERMINE THE ABILITY OF PERIPHERAL MARKERS OF THE MUCOSA OF THE SKIN TO DETECT STRESS RESPONSE, III) COMPLETE THE CHARACTERISATION OF HYPOTHALAME-HYPOPHYSARY-INTERRENAL AXIS COMPONENTS, AND IV) FINALLY VALIDATE THE NON-INVASIVE INDICATORS BY COMPARING THEIR RESPONSE WITH THE KNOWN CENTRAL INDICATORS (SPECIFIC OBJECTIVES 1 TO 4). _x000D_ for ACUICOLA PRACTICAL TIPICOL STRESSES THE ANALISIS OF THE EFFECTS OF AGENT DIVERSES. THUS, A SERIES OF FIVE MODEL EXPERIMENTS ARE PROJECTED WITH STRESSFUL AGENTS OF DIFFERENT TYPES. FIRST, TWO EXPERIMENTAL SITUATIONS OF INTEREST FOR ACUICOLA PRACTICE WILL BE ADDRESSED, WHICH CONSTITUTE TWO OF ITS SPECIFIC OBJECTIVES: CHRONIC STRESS BY DENSITY WITH SUBSTANCES THAT ATTENUATE THE ACTIVATION OF THE HYPOTHALAME-HYPOPHYSARY-INTERRENAL AXIS (SPECIFIC OBJECTIVE 5), AND II) STRESS INDUCED BY TRANSPORT AND USE OF ANESTHETICS UNDER SEDATION DOSES (SPECIFIC OBJECTIVE 6). ACCORDING TO THE CLASSICAL PARADIGM, THE ORDER OF ACTIVATION OF THE STRESS SYSTEM WOULD HAVE A DIRECTION FROM THE CENTER (HYPOTALAM) TO THE PERIPHERY. HOWEVER, THE INDUCTION DOES NOT NECESSARILY OCCUR IN THIS ORDER, BUT CAN BE INITIATED ON THE PERIPHERY. FOR THIS REASON THE PROJECT INCORPORATES THREE MORE EXPERIMENTAL DESIGNS THAT CONTEMPLATE THESE NEW APPROACH: TREATMENT WITH AFLATOXINS, TOXIC SUBSTANCES PRESENT IN FEED THAT ACT AT THE INTESTINAL LEVEL (SPECIFIC OBJECTIVE 7), II) TREATMENT WITH NANOPARTICULATES, EMERGING CONTAMINANTS PRESENT IN WATER (SPECIFIC OBJECTIVE 8), AND II) TREATMENT WITH VACCINE, AS A CLASSIC INMUNOGENIC ELEMENT (SPECIFIC OBJECTIVE 9). _x000D_ in ALL these EXPERIMENTS will be determined and awaited a comparison of the CENTRAL AND PERIFERICAL RESPONSE OF THIS, OF A MORE COMPANY AND INTEGRATED WAY OF THAT THAT THIS FROM THE PRESENT. FINALLY, BY VALIDATING THE CENTRAL VERSUS PERIPHERY RESPONSE, THE PROJECT AIMS TO PRESENT TO THE AQUACULTURE INDUSTRY THOSE INDICATORS OF STRESS THAT ARE MORE REPRESENTATIVE AND THAT CAN BE USED IN THE LEAST INVASIVE WAY POSSIBLE. IN THIS WAY, THE RESULTS CAN BE USED TO OPTIMISE THE CULTIVATION OF S. AURATA IN RELATION TO STRESS EPISODES. The results will be disseminated as well as by technical reports for the section._x000D_ In this project, there will be two CADIZ and BARCELONA EQUIPMENTS that come together with two important CHARACTERISTICS: I) EXPERIENCE IN THE FIELD OF FISH STRESS PHYSIOLOGY, AND II) THE ABILITY TO WORK AS A TEAM AND IN COLLABORATION, AS DEMONSTRATED ABOVE. (English)
12 October 2021
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Puerto Real
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Identifiers
AGL2016-76069-C2-1-R
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