Q3167758 (Q3167758): Difference between revisions
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(Created claim: summary (P836): With the aim of broadening the knowledge of the tuberculosis complex genome that facilitates an optimal strategy for TB control, we propose: 1.- Design a rapid diagnostic method of drug resistance that provides information on evolutionary lineage. 2.- Contrast genotypic and phenotypic resistances in clinical isolations of circulating MDR tuberculosis in our country since 1998. 3.- Analyse differential regions in the tuberculosis genome...) |
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With the aim of broadening the knowledge of the tuberculosis complex genome that facilitates an optimal strategy for TB control, we propose: 1.- Design a rapid diagnostic method of drug resistance that provides information on evolutionary lineage. 2.- Contrast genotypic and phenotypic resistances in clinical isolations of circulating MDR tuberculosis in our country since 1998. 3.- Analyse differential regions in the tuberculosis genome by genomic sequencing and assess its significance in pathogenesis and evolution. 4.- Study the microevolution of isolation due to a reactivation of tuberculosis in Aragon and identify the risk factors that may be associated. 5.- Geolocalise, visualise and spatially analyse the prevalence of tuberculosis. (English) | |||||||||||||||
| Property / summary: With the aim of broadening the knowledge of the tuberculosis complex genome that facilitates an optimal strategy for TB control, we propose: 1.- Design a rapid diagnostic method of drug resistance that provides information on evolutionary lineage. 2.- Contrast genotypic and phenotypic resistances in clinical isolations of circulating MDR tuberculosis in our country since 1998. 3.- Analyse differential regions in the tuberculosis genome by genomic sequencing and assess its significance in pathogenesis and evolution. 4.- Study the microevolution of isolation due to a reactivation of tuberculosis in Aragon and identify the risk factors that may be associated. 5.- Geolocalise, visualise and spatially analyse the prevalence of tuberculosis. (English) / rank | |||||||||||||||
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| Property / summary: With the aim of broadening the knowledge of the tuberculosis complex genome that facilitates an optimal strategy for TB control, we propose: 1.- Design a rapid diagnostic method of drug resistance that provides information on evolutionary lineage. 2.- Contrast genotypic and phenotypic resistances in clinical isolations of circulating MDR tuberculosis in our country since 1998. 3.- Analyse differential regions in the tuberculosis genome by genomic sequencing and assess its significance in pathogenesis and evolution. 4.- Study the microevolution of isolation due to a reactivation of tuberculosis in Aragon and identify the risk factors that may be associated. 5.- Geolocalise, visualise and spatially analyse the prevalence of tuberculosis. (English) / qualifier | |||||||||||||||
point in time: 12 October 2021
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Revision as of 16:23, 12 October 2021
Project Q3167758 in Spain
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | No label defined |
Project Q3167758 in Spain |
Statements
31,000.0 Euro
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62,000.0 Euro
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50.0 percent
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1 January 2019
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31 March 2022
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INSTITUTO ARAGONES DE CIENCIAS DE LA SALUD
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41°39'7.67"N, 0°52'51.38"W
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50297
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Con el objetivo de ampliar el conocimiento del genoma del complejo tuberculosis que facilite una estrategia óptima para el control de la TB, nos planteamos: 1.- Diseñar un método de diagnóstico rápido de resistencia a fármacos que proporcione información sobre linaje evolutivo. 2.- Contrastar las resistencias genotípicas y fenotípicas en aislamientos clínicos de tuberculosis MDR circulantes en nuestro país desde 1998. 3.- Analizar regiones diferenciales en el genoma de tuberculosis mediante secuenciación genómica y valorar su significado en la patogenia y evolución. 4.- Estudiar la microevolución de los aislamientos debidos a una reactivación de tuberculosis en Aragón e identificar los factores de riesgo que se puedan asociar. 5.- Geolocalizar, visualizar y analizar espacialmente la prevalencia de tuberculosis. (Spanish)
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With the aim of broadening the knowledge of the tuberculosis complex genome that facilitates an optimal strategy for TB control, we propose: 1.- Design a rapid diagnostic method of drug resistance that provides information on evolutionary lineage. 2.- Contrast genotypic and phenotypic resistances in clinical isolations of circulating MDR tuberculosis in our country since 1998. 3.- Analyse differential regions in the tuberculosis genome by genomic sequencing and assess its significance in pathogenesis and evolution. 4.- Study the microevolution of isolation due to a reactivation of tuberculosis in Aragon and identify the risk factors that may be associated. 5.- Geolocalise, visualise and spatially analyse the prevalence of tuberculosis. (English)
12 October 2021
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Zaragoza
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Identifiers
PI18_00336
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