Q3139142 (Q3139142): Difference between revisions
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(Created claim: summary (P836): Main objective: estimate the excess risk of chronic kidney disease (CKD) (stages 3-5) in cohorts of patients with resistant arterial hypertension (HRH) over a two-year follow-up period compared to a cohort of well-controlled hypertensives. Secondary objectives: identify patient factors related to the presence of HRH. Describe the pharmacological approach of patients with HTAR. Design: Prospective cohort study. Scope: multicenter in 8 health c...) |
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Main objective: estimate the excess risk of chronic kidney disease (CKD) (stages 3-5) in cohorts of patients with resistant arterial hypertension (HRH) over a two-year follow-up period compared to a cohort of well-controlled hypertensives. Secondary objectives: identify patient factors related to the presence of HRH. Describe the pharmacological approach of patients with HTAR. Design: Prospective cohort study. Scope: multicenter in 8 health centers in Madrid. Study population: of the 12,011 patients with high blood pressure from 8 health centers in Madrid, from the quotas of 40 family physicians, 667 will be studied in the HTAR cohort and 6,532 in the well-controlled HTA cohort. Exposure cohort shall be obtained from all those meeting HTAR criteria: HTA poorly controlled despite the use of 3 drugs, one of them diuretics, tested by MAPA and adherence to treatment. Control cohort: extracted from the same population quotas, well-controlled hypertensive in the last 6 months. For both cohorts, those that already have CRD shall be excluded. Data source: interview with patients, computerised medical history of Primary Care. Variables: sociodemographics, onset of CRD, TA control, medication, Diabetes Mellitus, cardiovascular disease. Data analysis: descriptive analysis, incidence rates of CRD in both cohorts, relative risk, relative risk reduction and absolute risk. Multivariate models by Cox regression. (English) | |||||||||||||||
| Property / summary: Main objective: estimate the excess risk of chronic kidney disease (CKD) (stages 3-5) in cohorts of patients with resistant arterial hypertension (HRH) over a two-year follow-up period compared to a cohort of well-controlled hypertensives. Secondary objectives: identify patient factors related to the presence of HRH. Describe the pharmacological approach of patients with HTAR. Design: Prospective cohort study. Scope: multicenter in 8 health centers in Madrid. Study population: of the 12,011 patients with high blood pressure from 8 health centers in Madrid, from the quotas of 40 family physicians, 667 will be studied in the HTAR cohort and 6,532 in the well-controlled HTA cohort. Exposure cohort shall be obtained from all those meeting HTAR criteria: HTA poorly controlled despite the use of 3 drugs, one of them diuretics, tested by MAPA and adherence to treatment. Control cohort: extracted from the same population quotas, well-controlled hypertensive in the last 6 months. For both cohorts, those that already have CRD shall be excluded. Data source: interview with patients, computerised medical history of Primary Care. Variables: sociodemographics, onset of CRD, TA control, medication, Diabetes Mellitus, cardiovascular disease. Data analysis: descriptive analysis, incidence rates of CRD in both cohorts, relative risk, relative risk reduction and absolute risk. Multivariate models by Cox regression. (English) / rank | |||||||||||||||
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| Property / summary: Main objective: estimate the excess risk of chronic kidney disease (CKD) (stages 3-5) in cohorts of patients with resistant arterial hypertension (HRH) over a two-year follow-up period compared to a cohort of well-controlled hypertensives. Secondary objectives: identify patient factors related to the presence of HRH. Describe the pharmacological approach of patients with HTAR. Design: Prospective cohort study. Scope: multicenter in 8 health centers in Madrid. Study population: of the 12,011 patients with high blood pressure from 8 health centers in Madrid, from the quotas of 40 family physicians, 667 will be studied in the HTAR cohort and 6,532 in the well-controlled HTA cohort. Exposure cohort shall be obtained from all those meeting HTAR criteria: HTA poorly controlled despite the use of 3 drugs, one of them diuretics, tested by MAPA and adherence to treatment. Control cohort: extracted from the same population quotas, well-controlled hypertensive in the last 6 months. For both cohorts, those that already have CRD shall be excluded. Data source: interview with patients, computerised medical history of Primary Care. Variables: sociodemographics, onset of CRD, TA control, medication, Diabetes Mellitus, cardiovascular disease. Data analysis: descriptive analysis, incidence rates of CRD in both cohorts, relative risk, relative risk reduction and absolute risk. Multivariate models by Cox regression. (English) / qualifier | |||||||||||||||
point in time: 12 October 2021
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Revision as of 13:23, 12 October 2021
Project Q3139142 in Spain
| Language | Label | Description | Also known as |
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| English | No label defined |
Project Q3139142 in Spain |
Statements
14,750.0 Euro
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29,500.0 Euro
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50.0 percent
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1 January 2017
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31 March 2020
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FUNDACION PARA LA INVESTIGACION E INNOVACION BIOMEDICA DE AT. PRIMARIA DE LA COMUNIDAD DE MADRID
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40°25'0.12"N, 3°42'12.89"W
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28079
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Objetivo principal: estimar el exceso de riesgo de enfermedad renal crónica (ERC) ( estadios 3-5) en cohorte de pacientes con hipertensión arterial resistente (HTAR) en un periodo de dos años de seguimiento comparado con cohorte de hipertensos bien controlados. Objetivos secundarios: identificar los factores del paciente relacionados con la presencia de HTAR . Describir el abordaje farmacológico de los pacientes con HTAR. Diseño: Estudio prospectivo de cohortes. Ambito: multicéntrico en 8 centros de salud de Madrid. Población de estudio: de los 12.011 pacientes con hipertensión arterial de 8 centros de salud de Madrid, de los cupos de 40 médicos de familia, serán estudiados 667 en la cohorte de HTAR y 6.532 en la cohorte de HTA bien controlada. Cohorte de exposición se obtendrá de todos los que reúnan criterios de HTAR: HTA mal controlada a pesar del uso de 3 fármacos, uno de ellos diuréticos, comprobado mediante MAPA y adherencia al tratamiento. Cohorte de control: extraída de los mismos cupos de población, hipertensos bien controlados en los últimos 6 meses. De ambas cohortes se excluirán los que ya tengan ERC. Fuente de datos: entrevista con los pacientes, historia clínica informatizada de Atención Primaria. Variables: sociodemográficas, aparición de ERC, control de TA, medicación, Diabetes Mellitus, enfermedad cardiovascular. Análisis de datos: análisis descriptivo, tasas de incidencia de ERC en ambas cohortes, riesgo relativo, reducción relativa del riesgo y riesgo absoluto. Modelos multivariantes mediante regresión de Cox. (Spanish)
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Main objective: estimate the excess risk of chronic kidney disease (CKD) (stages 3-5) in cohorts of patients with resistant arterial hypertension (HRH) over a two-year follow-up period compared to a cohort of well-controlled hypertensives. Secondary objectives: identify patient factors related to the presence of HRH. Describe the pharmacological approach of patients with HTAR. Design: Prospective cohort study. Scope: multicenter in 8 health centers in Madrid. Study population: of the 12,011 patients with high blood pressure from 8 health centers in Madrid, from the quotas of 40 family physicians, 667 will be studied in the HTAR cohort and 6,532 in the well-controlled HTA cohort. Exposure cohort shall be obtained from all those meeting HTAR criteria: HTA poorly controlled despite the use of 3 drugs, one of them diuretics, tested by MAPA and adherence to treatment. Control cohort: extracted from the same population quotas, well-controlled hypertensive in the last 6 months. For both cohorts, those that already have CRD shall be excluded. Data source: interview with patients, computerised medical history of Primary Care. Variables: sociodemographics, onset of CRD, TA control, medication, Diabetes Mellitus, cardiovascular disease. Data analysis: descriptive analysis, incidence rates of CRD in both cohorts, relative risk, relative risk reduction and absolute risk. Multivariate models by Cox regression. (English)
12 October 2021
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Madrid
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Identifiers
PI16_01609
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