PRE-CLINICAL DEVELOPMENT OF AN IP3K INHIBITOR FOR SOLID CANCER TREATMENT (Q2035314): Difference between revisions

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DESENVOLVIMENTO PRÉ-CLÍNICO DE UM INIBIDOR IP3K PARA TRATAMENTO SÓLIDO DO CANCRO
DESENVOLVIMENTO PRÉ-CLÍNICO DE UM INIBITOR IP3K PARA TRATAMENTO DE CANCRO SÓLIDO
Property / summary: THE PROJECT IS PROPOSED FOR THE PRE-CLINICAL CHARACTERISATION OF THE MEN1611, A NEW P3K INHIBITOR WHICH HAS THE CAPACITY TO BLOCK, IN A PREFERENTIAL MANNER, THE ALPHA, WILD, AND THE RANGE WHICH HAVE CHANGED. THE MOLECULAR DETERMINANTS OF AWARENESS WILL BE STUDIED. (English) / qualifier
 
readability score: 0.0057375662953202
Amount0.0057375662953202
Unit1
Property / summaryProperty / summary
O PROJETO É PROPOSTO PARA A CARACTERIZAÇÃO PRÉ-CLÍNICA DO MEN1611, UM NOVO INIBIDOR P3K QUE TEM A CAPACIDADE DE BLOQUEAR, DE FORMA PREFERENCIAL, O ALFA, SELVAGEM E O INTERVALO QUE MUDARAM. OS DETERMINANTES MOLECULARES DA CONSCIÊNCIA SERÃO ESTUDADOS. (Portuguese)
PROPOSTA-SE O PROJETO PARA A CARACTERIZAÇÃO PRÉ-CLÍNICA DO MEN1611, UM NOVO INIBITOR P3K QUE TEM A CAPACIDADE DE BLOQUEAR, DE UMA FORMA PREFERENCIAL, O ALPHA, O SELVAGEM E A GRANDE QUALIFICAÇÃO. Os DETERMINANTES MOLECULARES DE SENSIBILIZAÇÃO SERÃO ESTUDADOS. (Portuguese)
Property / contained in Local Administrative Unit
 
Property / contained in Local Administrative Unit: Pomezia / rank
 
Normal rank

Latest revision as of 06:10, 10 October 2024

Project Q2035314 in Italy
Language Label Description Also known as
English
PRE-CLINICAL DEVELOPMENT OF AN IP3K INHIBITOR FOR SOLID CANCER TREATMENT
Project Q2035314 in Italy

    Statements

    country
    Italy
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    EU contribution
    471,265.84 Euro
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    budget
    963,843.12 Euro
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    co-financing rate
    48.89 percent
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    start time
    28 December 2017
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    end time
    24 February 2021
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    expected end time
    6 July 2019
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    beneficiary name (string)
    MENARINI RICERCHE - S.P.A.
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    beneficiary
    Q282210
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    programme
    Lazio - ERDF
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    coordinate location

    41°40'3.11"N, 12°30'17.24"E
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    summary
    IL PROGETTO SI PROPONE LA CARATTERIZZAZIONE PRECLINICA DEL MEN1611, UN NUOVO INIBITORE DI PI3K CHE HA LA CAPACITà DI INIBIRE IN MODO PREFERENZIALE L?ISOFORMA ALFA, WILD TYPE E MUTATA. VERRANNO STUDIATI I DETERMINANTI MOLECOLARI DELLA SENSIBILITà (Italian)
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    THE PROJECT IS PROPOSED FOR THE PRE-CLINICAL CHARACTERISATION OF THE MEN1611, A NEW P3K INHIBITOR WHICH HAS THE CAPACITY TO BLOCK, IN A PREFERENTIAL MANNER, THE ALPHA, WILD, AND THE RANGE WHICH HAVE CHANGED. THE MOLECULAR DETERMINANTS OF AWARENESS WILL BE STUDIED. (English)
    readability score
    0.0057375662953202
    0 references
    LE PROJET PROPOSE LA CARACTÉRISATION PRÉCLINIQUE DU MEN1611, UN NOUVEL INHIBITEUR PI3K CAPABLE D’INHIBER PRÉFÉRENTIELLEMENT L’ISOFORME ALPHA, DE TYPE SAUVAGE ET MUTÉ. LES DÉTERMINANTS MOLÉCULAIRES DE LA SENSIBILITÉ SERONT ÉTUDIÉS (French)
    point in time
    16 December 2021
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    HET PROJECT STELT DE PREKLINISCHE KARAKTERISERING VAN DE MEN1611 VOOR, EEN NIEUWE PI3K-REMMER DIE DE MOGELIJKHEID HEEFT OM BIJ VOORKEUR HET ALFA-ISOFORM, WILDTYPE EN GEMUTEERD TE REMMEN. MOLECULAIRE DETERMINANTEN VAN GEVOELIGHEID ZULLEN WORDEN ONDERZOCHT (Dutch)
    point in time
    23 December 2021
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    DAS PROJEKT SCHLÄGT DIE PRÄKLINISCHE CHARAKTERISIERUNG DES MEN1611 VOR, EINEM NEUEN PI3K-INHIBITOR, DER DIE FÄHIGKEIT HAT, DIE ALPHA-ISOFORM, WILDE ART UND MUTATION BEVORZUGT ZU HEMMEN. MOLEKULARE DETERMINANTEN DER SENSITIVITÄT WERDEN UNTERSUCHT (German)
    point in time
    24 December 2021
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    EL PROYECTO PROPONE LA CARACTERIZACIÓN PRECLÍNICA DEL MEN1611, UN NUEVO INHIBIDOR PI3K QUE TIENE LA CAPACIDAD DE INHIBIR PREFERENTEMENTE LA ISOFORMA ALFA, SALVAJE Y MUTADA. SE ESTUDIARÁN LOS DETERMINANTES MOLECULARES DE LA SENSIBILIDAD (Spanish)
    point in time
    25 January 2022
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    PROJEKTET FORESLÅS MED HENBLIK PÅ DEN PRÆKLINISKE KARAKTERISERING AF MEN1611, EN NY P3K-HÆMMER, SOM HAR KAPACITET TIL AT BLOKERE ALFA, WILD OG DET ÆNDREDE INTERVAL. DE MOLEKYLÆRE DETERMINANTER FOR BEVIDSTHED VIL BLIVE UNDERSØGT. (Danish)
    point in time
    5 July 2022
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    ΤΟ ΈΡΓΟ ΠΡΟΤΕΊΝΕΤΑΙ ΓΙΑ ΤΟΝ ΠΡΟΚΛΙΝΙΚΌ ΧΑΡΑΚΤΗΡΙΣΜΌ ΤΟΥ MEN1611, ΕΝΌΣ ΝΈΟΥ ΑΝΑΣΤΟΛΈΑ P3K ΠΟΥ ΈΧΕΙ ΤΗΝ ΙΚΑΝΌΤΗΤΑ ΝΑ ΜΠΛΟΚΆΡΕΙ, ΚΑΤΆ ΠΡΟΤΊΜΗΣΗ, ΤΟ ΆΛΦΑ, ΤΟ ΆΓΡΙΟ ΚΑΙ ΤΟ ΕΎΡΟΣ ΠΟΥ ΈΧΕΙ ΑΛΛΆΞΕΙ. ΘΑ ΜΕΛΕΤΗΘΟΎΝ ΟΙ ΜΟΡΙΑΚΟΊ ΚΑΘΟΡΙΣΤΙΚΟΊ ΠΑΡΆΓΟΝΤΕΣ ΤΗΣ ΕΥΑΙΣΘΗΤΟΠΟΊΗΣΗΣ. (Greek)
    point in time
    5 July 2022
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    PROJEKT JE PREDLOŽEN ZA PRETKLINIČKU KARAKTERIZACIJU MEN1611, NOVOG P3K INHIBITORA KOJI MOŽE NA POVLAŠTENI NAČIN BLOKIRATI ALFA, DIVLJE I RASPON KOJI SU SE PROMIJENILI. PROUČAVAT ĆE SE MOLEKULARNE ODREDNICE SVIJESTI. (Croatian)
    point in time
    5 July 2022
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    PROIECTUL ESTE PROPUS PENTRU CARACTERIZAREA PRECLINICĂ A MEN1611, UN NOU INHIBITOR P3K CARE ARE CAPACITATEA DE A BLOCA, ÎN MOD PREFERENȚIAL, ALFA, SĂLBATIC ȘI GAMA CARE S-A SCHIMBAT. FACTORII MOLECULARI DETERMINANȚI AI CONȘTIENTIZĂRII VOR FI STUDIAȚI. (Romanian)
    point in time
    5 July 2022
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    PROJEKT JE NAVRHNUTÝ PRE PREDKLINICKÚ CHARAKTERIZÁCIU MEN1611, NOVÉHO INHIBÍTORA P3K, KTORÝ MÁ SCHOPNOSŤ PREDNOSTNE BLOKOVAŤ ALFA, DIVOKÝ A ROZSAH, KTORÝ SA ZMENIL. MOLEKULÁRNE DETERMINANTY POVEDOMIA SA BUDÚ SKÚMAŤ. (Slovak)
    point in time
    5 July 2022
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    IL-PROĠETT HUWA PROPOST GĦALL-KARATTERIZZAZZJONI PREKLINIKA TAL-MEN1611, INIBITUR P3K ĠDID LI GĦANDU L-KAPAĊITÀ LI JIMBLOKKA, B’MOD PREFERENZJALI, L-ALFA, IS-SELVAĠĠ, U L-FIRXA LI NBIDLU. ID-DETERMINANTI MOLEKULARI TAL-GĦARFIEN SE JIĠU STUDJATI. (Maltese)
    point in time
    5 July 2022
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    PROPOSTA-SE O PROJETO PARA A CARACTERIZAÇÃO PRÉ-CLÍNICA DO MEN1611, UM NOVO INIBITOR P3K QUE TEM A CAPACIDADE DE BLOQUEAR, DE UMA FORMA PREFERENCIAL, O ALPHA, O SELVAGEM E A GRANDE QUALIFICAÇÃO. Os DETERMINANTES MOLECULARES DE SENSIBILIZAÇÃO SERÃO ESTUDADOS. (Portuguese)
    point in time
    5 July 2022
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    HANKKEELLE EHDOTETAAN MEN1611:N ESIKLIINISTÄ LUONNEHDINTAA, JOKA ON UUSI P3K-INHIBIITTORI, JOKA PYSTYY ENSISIJAISESTI ESTÄMÄÄN ALFAN, VILLIN JA MUUTTUNEEN ALUEEN. TIETOISUUDEN MOLEKULAARISIA TAUSTATEKIJÖITÄ TUTKITAAN. (Finnish)
    point in time
    5 July 2022
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    PROJEKT PROPONUJE SIĘ DLA PRZEDKLINICZNEJ CHARAKTERYSTYKI MEN1611, NOWEGO INHIBITORA P3K, KTÓRY MA ZDOLNOŚĆ BLOKOWANIA, W SPOSÓB UPRZYWILEJOWANY, ALFA, DZIKIEGO I ZMIENIONEGO ZAKRESU. MOLEKULARNE WYZNACZNIKI ŚWIADOMOŚCI ZOSTANĄ ZBADANE. (Polish)
    point in time
    5 July 2022
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    PROJEKT JE PREDLAGAN ZA PREDKLINIČNO KARAKTERIZACIJO MEN1611, NOVEGA ZAVIRALCA P3K, KI IMA SPOSOBNOST, DA PREDNOSTNO BLOKIRA ALFA, DIVJINO IN OBSEG, KI SO SE SPREMENILI. PROUČILI BOMO MOLEKULARNE DETERMINANTE ZAVEDANJA. (Slovenian)
    point in time
    5 July 2022
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    PROJEKT JE NAVRŽEN PRO PŘEDKLINICKÉ CHARAKTERIZACI MEN1611, NOVÉHO INHIBITORU P3K, KTERÝ MÁ SCHOPNOST PREFERENČNÍM ZPŮSOBEM BLOKOVAT ALFA, DIVOCE A ROZSAH, KTERÝ SE ZMĚNIL. MOLEKULÁRNÍ DETERMINANTY POVĚDOMÍ BUDOU STUDOVÁNY. (Czech)
    point in time
    5 July 2022
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    PROJEKTAS SIŪLOMAS DĖL NAUJO P3K INHIBITORIAUS MEN1611, KURIS GALI PIRMUMO TVARKA BLOKUOTI ALFA, LAUKINĮ IR PASIKEITUSĮ DIAPAZONĄ, IKIKLINIKINIO APIBŪDINIMO. BUS TIRIAMI MOLEKULINIAI SĄMONINGUMO VEIKSNIAI. (Lithuanian)
    point in time
    5 July 2022
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    PROJEKTS IR IEROSINĀTS MEN1611 — JAUNA P3K INHIBITORA — PREKLĪNISKAJAI RAKSTUROŠANAI, KAS SPĒJ PREFERENCIĀLĀ VEIDĀ BLOĶĒT ALFA, SAVVAĻĀ UN AMPLITŪDĀ, KAS IR MAINĪJUSIES. TIKS PĒTĪTI IZPRATNES MOLEKULĀRIE FAKTORI. (Latvian)
    point in time
    5 July 2022
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    ПРОЕКТЪТ Е ПРЕДЛОЖЕН ЗА ПРЕДКЛИНИЧНА ХАРАКТЕРИСТИКА НА MEN1611, НОВ P3K ИНХИБИТОР, КОЙТО ИМА СПОСОБНОСТТА ДА БЛОКИРА, ПО ПРЕФЕРЕНЦИАЛЕН НАЧИН, АЛФА, ДИВА ПРИРОДА И ПРОМЕНЕНАТА ГАМА. ЩЕ БЪДАТ ПРОУЧЕНИ МОЛЕКУЛЯРНИТЕ ДЕТЕРМИНАНТИ НА ОСЪЗНАВАНЕТО. (Bulgarian)
    point in time
    5 July 2022
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    A PROJEKT A MEN1611 – EGY ÚJ P3K-GÁTLÓ – PREKLINIKAI JELLEMZÉSÉRE VONATKOZIK, AMELY LEHETŐVÉ TESZI, HOGY PREFERENCIÁLIS MÓDON BLOKKOLJA AZ ALFA, A VAD ÉS A MEGVÁLTOZOTT TARTOMÁNYT. A TUDATOSSÁG MOLEKULÁRIS MEGHATÁROZÓIT TANULMÁNYOZZÁK. (Hungarian)
    point in time
    5 July 2022
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    TÁ AN TIONSCADAL BEARTAITHE DO THRÉITHRIÚ RÉAMHCHLINICIÚIL AN MEN1611, COSCAIRE P3K NUA A BHFUIL SÉ DE CHUMAS AIGE AN ALFA, AN FIÁIN AGUS AN RAON ATÁ ATHRAITHE A BHLOCÁIL AR BHEALACH FABHRACH. DÉANFAR STAIDÉAR AR NA DEITÉARMANAINT MHÓILÍNEACHA FEASACHTA. (Irish)
    point in time
    5 July 2022
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    PROJEKTET FÖRESLÅS FÖR PREKLINISK KARAKTERISERING AV MEN1611, EN NY P3K-HÄMMARE SOM HAR KAPACITET ATT PÅ ETT FÖRMÅNLIGT SÄTT BLOCKERA ALFA, WILD OCH DET OMRÅDE SOM HAR FÖRÄNDRATS. DE MOLEKYLÄRA BESTÄMNINGSFAKTORERNA FÖR MEDVETENHET KOMMER ATT STUDERAS. (Swedish)
    point in time
    5 July 2022
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    PROJEKT ON KAVANDATUD UUE P3K INHIBIITORI MEN1611 PREKLIINILISEKS ISELOOMUSTAMISEKS, MIS SUUDAB EELISTATULT BLOKEERIDA MUUTUNUD ALFA-, METSIKU JA VAHEMIKU. UURITAKSE TEADLIKKUSE MOLEKULAARSEID DETERMINANTE. (Estonian)
    point in time
    5 July 2022
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    location (string)
    POMEZIA
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    date of last update
    8 April 2023
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    Identifiers

    Italian Unique Project Code
    F57H18000070007
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