Innovative polymeric composites for bone loss (Q84127): Difference between revisions
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(Removed claim: summary (P836): There is currently an increase in the number of orthopaedic and dental procedures that require the use of materials filled with bone losses.Most of the products for such applications are flawed, including in particular:uncontrolled resorption, low osteinductance, inadequate strength parameters, no supporting application form.For these reasons, there are growing interest in both plastic and injection systems with a fully resorption and osteoind...) |
(Created claim: summary (P836): Today, the number of orthopaedic and dental procedures requiring the use of biomaterials to fill bone defects is increasing worldwide. Most of the products dedicated to this type of use are affected by defects, including in particular: uncontrolled resorption, low osteoinductivity, insufficient endurance parameters, bulky application form. For these reasons, plastic and injective systems, containing fully resorbable and osteoinductive church rep...) |
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Today, the number of orthopaedic and dental procedures requiring the use of biomaterials to fill bone defects is increasing worldwide. Most of the products dedicated to this type of use are affected by defects, including in particular: uncontrolled resorption, low osteoinductivity, insufficient endurance parameters, bulky application form. For these reasons, plastic and injective systems, containing fully resorbable and osteoinductive church replacement materials, are increasingly popular. In response to this demand, new polymer biocompositions containing innovative patented nanohydroxyapatite (nhap) will be developed and marketed as a result of the project. Based on the principle of biomimethism of the natural bone structure, a product will be created optimally combining the organic and mineral phases. His distinguishing features will be: • presence of Hap nanoparticles, conducive to bone regeneration, • improved mechanical properties and consistency in vivo conditions, thanks to the use of polymers, • optimised application method. As part of the research work – six stages have been planned for development: I – optimised nhap synthesis, II – creating composites based on nhap, III – modifications of polymer composites, IV – in vitro and in vivo tests of product prototypes, V – transfer of production scale from laboratory to industrial, VI – clinical trials of the product. Innovative approach to the production of materials included in products and care for high quality while minimising production costs will ensure high competitiveness of biocompositors. The products obtained will have osteoinductive, osteoconductive and osteointegrative properties. (English) | |||||||||||||||
| Property / summary: Today, the number of orthopaedic and dental procedures requiring the use of biomaterials to fill bone defects is increasing worldwide. Most of the products dedicated to this type of use are affected by defects, including in particular: uncontrolled resorption, low osteoinductivity, insufficient endurance parameters, bulky application form. For these reasons, plastic and injective systems, containing fully resorbable and osteoinductive church replacement materials, are increasingly popular. In response to this demand, new polymer biocompositions containing innovative patented nanohydroxyapatite (nhap) will be developed and marketed as a result of the project. Based on the principle of biomimethism of the natural bone structure, a product will be created optimally combining the organic and mineral phases. His distinguishing features will be: • presence of Hap nanoparticles, conducive to bone regeneration, • improved mechanical properties and consistency in vivo conditions, thanks to the use of polymers, • optimised application method. As part of the research work – six stages have been planned for development: I – optimised nhap synthesis, II – creating composites based on nhap, III – modifications of polymer composites, IV – in vitro and in vivo tests of product prototypes, V – transfer of production scale from laboratory to industrial, VI – clinical trials of the product. Innovative approach to the production of materials included in products and care for high quality while minimising production costs will ensure high competitiveness of biocompositors. The products obtained will have osteoinductive, osteoconductive and osteointegrative properties. (English) / rank | |||||||||||||||
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| Property / summary: Today, the number of orthopaedic and dental procedures requiring the use of biomaterials to fill bone defects is increasing worldwide. Most of the products dedicated to this type of use are affected by defects, including in particular: uncontrolled resorption, low osteoinductivity, insufficient endurance parameters, bulky application form. For these reasons, plastic and injective systems, containing fully resorbable and osteoinductive church replacement materials, are increasingly popular. In response to this demand, new polymer biocompositions containing innovative patented nanohydroxyapatite (nhap) will be developed and marketed as a result of the project. Based on the principle of biomimethism of the natural bone structure, a product will be created optimally combining the organic and mineral phases. His distinguishing features will be: • presence of Hap nanoparticles, conducive to bone regeneration, • improved mechanical properties and consistency in vivo conditions, thanks to the use of polymers, • optimised application method. As part of the research work – six stages have been planned for development: I – optimised nhap synthesis, II – creating composites based on nhap, III – modifications of polymer composites, IV – in vitro and in vivo tests of product prototypes, V – transfer of production scale from laboratory to industrial, VI – clinical trials of the product. Innovative approach to the production of materials included in products and care for high quality while minimising production costs will ensure high competitiveness of biocompositors. The products obtained will have osteoinductive, osteoconductive and osteointegrative properties. (English) / qualifier | |||||||||||||||
point in time: 14 October 2020
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Revision as of 14:30, 14 October 2020
Project in Poland financed by DG Regio
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | Innovative polymeric composites for bone loss |
Project in Poland financed by DG Regio |
Statements
4,566,444.0 zloty
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6,274,385.0 zloty
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72.78 percent
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1 January 2016
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31 December 2020
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BIOVICO SP. Z O. O.
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Obecnie na świecie obserwuje się wzrost liczby procedur ortopedycznych i dentystycznych wymagających użycia biomateriałów wypełniających ubytki kostne. Większość produktów dedykowanych tego rodzaju zastosowaniom, obarczona jest wadami, w tym w szczególności: niekontrolowaną resorpcją, niską osteoindukcyjnością, niedostatecznymi parametrami wytrzymałościowymi, nieporęczną formą aplikacyjną. Z tych względów rosnącym zainteresowaniem cieszą się systemy plastyczne oraz iniekcyjne, zawierające w pełni resorbowalne i osteoindukcyjne materiały kościozastępcze. W odpowiedzi na to zapotrzebowanie, w wyniku realizacji projektu, opracowane i wprowadzone na rynek zostaną nowe biokompozyty polimerowe, zawierające innowacyjny opatentowany nanohydroksyapatyt (nHAp). Opierając się o zasadę biomimetyzmu naturalnej struktury kości, stworzony zostanie produkt optymalnie łączący fazę organiczną i mineralną. Jego wyróżnikami będą: • obecność nanocząstek HAp, sprzyjająca odtwarzaniu kości, • poprawione właściwości mechaniczne i spójność w warunkach in vivo, dzięki zastosowaniu polimerów, • zoptymalizowany sposób aplikacji. W ramach prac badawczo – rozwojowych zaplanowano sześć etapów: I - zoptymalizowany proces syntezy nHAp, II - stworzenie kompozytów na bazie nHAp, III – modyfikacje kompozytów polimerami, IV - badania in vitro oraz in vivo prototypów produktu, V - przeniesienie skali produkcyjnej z laboratoryjnej na przemysłową, VI - badania kliniczne produktu. Innowacyjne podejście do produkcji materiałów wchodzących w skład produktów oraz dbałość o wysoką jakość przy minimalizacji kosztów produkcji, zapewni wysoką konkurencyjność biokompozytów. Otrzymane produkty będą posiadały właściwości osteoindukcyjne, osteokondukcyjne oraz osteointegracyjne. (Polish)
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Today, the number of orthopaedic and dental procedures requiring the use of biomaterials to fill bone defects is increasing worldwide. Most of the products dedicated to this type of use are affected by defects, including in particular: uncontrolled resorption, low osteoinductivity, insufficient endurance parameters, bulky application form. For these reasons, plastic and injective systems, containing fully resorbable and osteoinductive church replacement materials, are increasingly popular. In response to this demand, new polymer biocompositions containing innovative patented nanohydroxyapatite (nhap) will be developed and marketed as a result of the project. Based on the principle of biomimethism of the natural bone structure, a product will be created optimally combining the organic and mineral phases. His distinguishing features will be: • presence of Hap nanoparticles, conducive to bone regeneration, • improved mechanical properties and consistency in vivo conditions, thanks to the use of polymers, • optimised application method. As part of the research work – six stages have been planned for development: I – optimised nhap synthesis, II – creating composites based on nhap, III – modifications of polymer composites, IV – in vitro and in vivo tests of product prototypes, V – transfer of production scale from laboratory to industrial, VI – clinical trials of the product. Innovative approach to the production of materials included in products and care for high quality while minimising production costs will ensure high competitiveness of biocompositors. The products obtained will have osteoinductive, osteoconductive and osteointegrative properties. (English)
14 October 2020
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Identifiers
POIR.04.01.04-00-0133/15
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