Preparation of candidates for drugs in psychotic and cognitive therapy (Q77688): Difference between revisions
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(Removed claim: summary (P836): The aim of the project is to develop a candidate for an innovative medicine in the therapy of psychotic disorders, in particular the type of Alzheimer’s Disease (“Alzheimer’s”).Dementia of Alzheimer’s & leaves;DATES).The essential functionality of the project will be the pharmacological activity of a new candidate in medicine which is superior in terms of effectiveness and/or security for competitive cures.It should be noted in this regard tha...) |
(Created claim: summary (P836): The aim of the project is to develop a candidate for an innovative drug in the treatment of psychotic disorders in dementia, especially Alzheimer’s type. Dementia of Alzheimer’s IT’S DAT. The main functionality of the project result will be the pharmacological activity of the new candidate for the medicine, which exceeds the competitive therapies in terms of efficacy and/or safety. It should be noted that there is currently no pharmacotherapy de...) |
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The aim of the project is to develop a candidate for an innovative drug in the treatment of psychotic disorders in dementia, especially Alzheimer’s type. Dementia of Alzheimer’s IT’S DAT. The main functionality of the project result will be the pharmacological activity of the new candidate for the medicine, which exceeds the competitive therapies in terms of efficacy and/or safety. It should be noted that there is currently no pharmacotherapy developed specifically for psychotic disorders in dementia, e.g. Alzheimer’s type, and antipsychotics, with an indication for the treatment of schizophrenia, are not authorised for the treatment of patients with dementia, mainly due to serious life-threatening adverse reactions. Meanwhile, it is estimated that the number of patients with dementia has already exceeded 30 million worldwide and is expected to triple over the next 50 years due to population ageing. This project therefore addresses a very important, unmet medical need. The result of the project is to be an innovative molecule, selected for preclinical development based on the results of extended pharmacological characteristics, then characterised in Phase 1 and 2a clinical trials, i.e. proof-of-concept studies in patients with dementia psychosis, ready for further clinical development and commercialisation in the form of biopartnering. An important element of the therapeutic value of the candidate for a drug and distinguishing him from current market competition is its innovative mechanism of action. Reference number of the aid programme: SA.41471(2015/X) Purpose of public aid: Article 25 of EC Regulation No 651/2014 of 17 June 2014 declaring certain types of aid compatible with the internal market in the application of Articles 107 and 108 of the Treaty (OJ L. I'm sorry. EU L 187/1 of 26.06.2014). (English) | |||||||||||||||
| Property / summary: The aim of the project is to develop a candidate for an innovative drug in the treatment of psychotic disorders in dementia, especially Alzheimer’s type. Dementia of Alzheimer’s IT’S DAT. The main functionality of the project result will be the pharmacological activity of the new candidate for the medicine, which exceeds the competitive therapies in terms of efficacy and/or safety. It should be noted that there is currently no pharmacotherapy developed specifically for psychotic disorders in dementia, e.g. Alzheimer’s type, and antipsychotics, with an indication for the treatment of schizophrenia, are not authorised for the treatment of patients with dementia, mainly due to serious life-threatening adverse reactions. Meanwhile, it is estimated that the number of patients with dementia has already exceeded 30 million worldwide and is expected to triple over the next 50 years due to population ageing. This project therefore addresses a very important, unmet medical need. The result of the project is to be an innovative molecule, selected for preclinical development based on the results of extended pharmacological characteristics, then characterised in Phase 1 and 2a clinical trials, i.e. proof-of-concept studies in patients with dementia psychosis, ready for further clinical development and commercialisation in the form of biopartnering. An important element of the therapeutic value of the candidate for a drug and distinguishing him from current market competition is its innovative mechanism of action. Reference number of the aid programme: SA.41471(2015/X) Purpose of public aid: Article 25 of EC Regulation No 651/2014 of 17 June 2014 declaring certain types of aid compatible with the internal market in the application of Articles 107 and 108 of the Treaty (OJ L. I'm sorry. EU L 187/1 of 26.06.2014). (English) / rank | |||||||||||||||
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| Property / summary: The aim of the project is to develop a candidate for an innovative drug in the treatment of psychotic disorders in dementia, especially Alzheimer’s type. Dementia of Alzheimer’s IT’S DAT. The main functionality of the project result will be the pharmacological activity of the new candidate for the medicine, which exceeds the competitive therapies in terms of efficacy and/or safety. It should be noted that there is currently no pharmacotherapy developed specifically for psychotic disorders in dementia, e.g. Alzheimer’s type, and antipsychotics, with an indication for the treatment of schizophrenia, are not authorised for the treatment of patients with dementia, mainly due to serious life-threatening adverse reactions. Meanwhile, it is estimated that the number of patients with dementia has already exceeded 30 million worldwide and is expected to triple over the next 50 years due to population ageing. This project therefore addresses a very important, unmet medical need. The result of the project is to be an innovative molecule, selected for preclinical development based on the results of extended pharmacological characteristics, then characterised in Phase 1 and 2a clinical trials, i.e. proof-of-concept studies in patients with dementia psychosis, ready for further clinical development and commercialisation in the form of biopartnering. An important element of the therapeutic value of the candidate for a drug and distinguishing him from current market competition is its innovative mechanism of action. Reference number of the aid programme: SA.41471(2015/X) Purpose of public aid: Article 25 of EC Regulation No 651/2014 of 17 June 2014 declaring certain types of aid compatible with the internal market in the application of Articles 107 and 108 of the Treaty (OJ L. I'm sorry. EU L 187/1 of 26.06.2014). (English) / qualifier | |||||||||||||||
point in time: 14 October 2020
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Revision as of 10:05, 14 October 2020
Project in Poland financed by DG Regio
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | Preparation of candidates for drugs in psychotic and cognitive therapy |
Project in Poland financed by DG Regio |
Statements
25,796,383.65 zloty
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55,502,648.21 zloty
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46.48 percent
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1 June 2017
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31 December 2023
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ADAMED SP. Z O.O.
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52°23'26.2"N, 20°44'2.0"E
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Celem projektu jest opracowanie kandydata na lek innowacyjny w terapii zaburzeń psychotycznych w otępieniu, szczególnie typu Alzheimerowskiego (ang. Dementia of Alzheimer’s type – DAT). Zasadniczą funkcjonalnością rezultatu projektu będzie aktywność farmakologiczna nowego kandydata na lek, przewyższająca pod względem skuteczności i/lub bezpieczeństwa terapie konkurencyjne. Należy przy tym zaznaczyć, że aktualnie nie istnieje farmakoterapia opracowana w sposób dedykowany zaburzeniom psychotycznym w otępieniu, np. typu Alzheimerowskiego, a leki przeciwpsychotyczne, ze wskazaniem do leczenia schizofrenii, nie są dopuszczone do terapii pacjentów z otępieniem, głównie z uwagi na poważne, zagrażające życiu działania niepożądane. Tymczasem szacuje się, że w skali świata liczba pacjentów z zaburzeniami psychotycznymi w otępieniu przekroczyła już 30 mln i w związku ze starzeniem się społeczeństw, w ciągu najbliższych 50 lat ma ulec potrojeniu. Niniejszy projekt adresuje więc bardzo ważną, niezaspokojoną potrzebę medyczną. Rezultatem projektu ma być innowacyjna molekuła, wyłoniona do rozwoju przedklinicznego na podstawie wyników poszerzonej charakterystyki farmakologicznej, scharakteryzowana następnie w badaniach klinicznych fazy 1 oraz 2a, czyli badaniach proof-of-concept u pacjentów z psychozą w otępieniu, gotowa do dalszego rozwoju klinicznego i komercjalizacji w formie biopartneringu. Istotnym elementem stanowiącym o wartości terapeutycznej opracowywanego kandydata na lek i odróżniającym go od aktualnej konkurencji rynkowej jest jego innowacyjny mechanizm działania. Numer_referencyjny_programu_pomocowego: SA.41471(2015/X) Przeznaczenie_pomocy_publicznej: art. 25 rozporządzenia KE nr 651/2014 z dnia 17 czerwca 2014 r. uznające niektóre rodzaje pomocy za zgodne z rynkiem wewnętrznym w stosowaniu art. 107 i 108 Traktatu (Dz. Urz. UE L 187/1 z 26.06.2014). (Polish)
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The aim of the project is to develop a candidate for an innovative drug in the treatment of psychotic disorders in dementia, especially Alzheimer’s type. Dementia of Alzheimer’s IT’S DAT. The main functionality of the project result will be the pharmacological activity of the new candidate for the medicine, which exceeds the competitive therapies in terms of efficacy and/or safety. It should be noted that there is currently no pharmacotherapy developed specifically for psychotic disorders in dementia, e.g. Alzheimer’s type, and antipsychotics, with an indication for the treatment of schizophrenia, are not authorised for the treatment of patients with dementia, mainly due to serious life-threatening adverse reactions. Meanwhile, it is estimated that the number of patients with dementia has already exceeded 30 million worldwide and is expected to triple over the next 50 years due to population ageing. This project therefore addresses a very important, unmet medical need. The result of the project is to be an innovative molecule, selected for preclinical development based on the results of extended pharmacological characteristics, then characterised in Phase 1 and 2a clinical trials, i.e. proof-of-concept studies in patients with dementia psychosis, ready for further clinical development and commercialisation in the form of biopartnering. An important element of the therapeutic value of the candidate for a drug and distinguishing him from current market competition is its innovative mechanism of action. Reference number of the aid programme: SA.41471(2015/X) Purpose of public aid: Article 25 of EC Regulation No 651/2014 of 17 June 2014 declaring certain types of aid compatible with the internal market in the application of Articles 107 and 108 of the Treaty (OJ L. I'm sorry. EU L 187/1 of 26.06.2014). (English)
14 October 2020
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Identifiers
POIR.01.01.01-00-0108/17
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