Infrastructure for metabolomics research and medical chemistry (Q4301070): Difference between revisions

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Revision as of 11:48, 22 June 2022

Project Q4301070 in Austria, Czechia
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Infrastructure for metabolomics research and medical chemistry
Project Q4301070 in Austria, Czechia

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    1,065,409.89 Euro
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    1,253,423.4 Euro
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    85.0 percent
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    1 March 2017
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    29 February 2020
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    The Biology Centre of the CAS, v. v. i.
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    Q4374898 (Deleted Item)
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    48°20'15.47"N, 14°19'22.15"E
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    48°58'41.38"N, 14°26'45.02"E
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    A state-of-the-art study of the metabolism and metabolic status of cells, tissues and organisms is building on the application of the "omics" approach to metabolomics. This research field requires a high level of expertise due to the variety of metabolite structures, the complexity of biological samples and the technology used. In the regions of South Bohemia and Upper Austria, individual locations exist which possess expertise in specific sectors of metabolomics research, however, coordination of the activities can lead to a significant increase in efficiency for all stakeholders. Therefore, a key factor seems to be establishing long-term cooperation between the Biology Centre and the Johannes Kepler University, as well as with strategic regional partners, within which a complementary infrastructure can be established that enables international scientific research. The project proposal is in line with the South Bohemian RIS3 strategy and has been implemented in the action plan, project no. 33, “New Metabolomic Technologies”. Furthermore, the project is part of the action field of "Health - Aging Society" in the strategic programme "Innovative Upper Austria 2020". The project involves the construction of two research laboratories equipped with state-of-the-art mass spectrometry for "targeted" and "non-targeted" metabolomics analysis. The following 9 key results are to be achieved in the project: (1) the Interreg network METABO-BL of the 10 partners, (2) efficient use of existing knowledge and infrastructure, (3) the establishment of two new complementary laboratories, (4) the creation of two joint research teams, (5) joint development of new analytical metabolomics platforms, (6) the joint submission of a research project, (7) proof of concept with 3 pilot research projects, (8) an increase of the number of top publications , (9) the metabolomics course for students in the programme area, (10) sustainable development of research cooperation within a European context. A detailed description is provided in Annex C00/I-III, p. 2-5. Efficient use of the established infrastructure will ensure cooperation with regional strategic partners: (1) Budweis Hospital, (2) University of South Bohemia, (3) the South Bohemia Science Technology Park, (4) Institute of Laboratory Diagnostics Kepler Klinikum Linz, (5) Institute for Bioinformatics JKU, (6) Institute for Analytical Chemistry, University of Vienna (see Annex C00/IV, p. 4-8). The implementation of the project is ensured with 5 work packages, the purchase of equipment, the commissioning of the new laboratories (WP I1-I2), the training of the personnel, the implementation of existing and new/in-development methods (WP T1-T2) and their application in the Metabo-BL network as well as international cooperation. The validity of the concept will be tested with 3 pilot projects (WP T3). More in Annex C00. (English)
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