Q3697194 (Q3697194): Difference between revisions
Jump to navigation
Jump to search
(Changed label, description and/or aliases in en: Setting new description) |
(Created claim: summary (P836): Once heart failure (CI) is installed, it is responsible for high mortality and frequent hospitalisations (first cause of hospitalisation in subjects >65 years), as well as very high social and economic costs. Our team aims to improve the risk characterisation of IC, especially by protein biomarkers (BMs) or circulating RNAs. The co-financing under consideration for this application is RHU Fight-HF: it is a hospital-university research program (...) |
||||||||||||||
| Property / summary | |||||||||||||||
Once heart failure (CI) is installed, it is responsible for high mortality and frequent hospitalisations (first cause of hospitalisation in subjects >65 years), as well as very high social and economic costs. Our team aims to improve the risk characterisation of IC, especially by protein biomarkers (BMs) or circulating RNAs. The co-financing under consideration for this application is RHU Fight-HF: it is a hospital-university research program (RHU) labeled by PIA2 Future Investments via the ANR. The Fight-HF project is one of the 4 programmes selected by the international jury during the first wave of this national call for tenders: the only non-Paris project. The detection of early forms of ICR through simple biological measurements in participants in the Stanislas Family Orraine Cohort, which is exceptional globally (family, 20 years of follow-up, cardiovascular phenopathy research) will pave the way for large-scale screening to identify subjects with CI at an early stage and allow for more intensive management aimed at stabilising it at early stages by the management of cardiovascular risk factors, and possibly of developing therapies. (English) | |||||||||||||||
| Property / summary: Once heart failure (CI) is installed, it is responsible for high mortality and frequent hospitalisations (first cause of hospitalisation in subjects >65 years), as well as very high social and economic costs. Our team aims to improve the risk characterisation of IC, especially by protein biomarkers (BMs) or circulating RNAs. The co-financing under consideration for this application is RHU Fight-HF: it is a hospital-university research program (RHU) labeled by PIA2 Future Investments via the ANR. The Fight-HF project is one of the 4 programmes selected by the international jury during the first wave of this national call for tenders: the only non-Paris project. The detection of early forms of ICR through simple biological measurements in participants in the Stanislas Family Orraine Cohort, which is exceptional globally (family, 20 years of follow-up, cardiovascular phenopathy research) will pave the way for large-scale screening to identify subjects with CI at an early stage and allow for more intensive management aimed at stabilising it at early stages by the management of cardiovascular risk factors, and possibly of developing therapies. (English) / rank | |||||||||||||||
Normal rank | |||||||||||||||
| Property / summary: Once heart failure (CI) is installed, it is responsible for high mortality and frequent hospitalisations (first cause of hospitalisation in subjects >65 years), as well as very high social and economic costs. Our team aims to improve the risk characterisation of IC, especially by protein biomarkers (BMs) or circulating RNAs. The co-financing under consideration for this application is RHU Fight-HF: it is a hospital-university research program (RHU) labeled by PIA2 Future Investments via the ANR. The Fight-HF project is one of the 4 programmes selected by the international jury during the first wave of this national call for tenders: the only non-Paris project. The detection of early forms of ICR through simple biological measurements in participants in the Stanislas Family Orraine Cohort, which is exceptional globally (family, 20 years of follow-up, cardiovascular phenopathy research) will pave the way for large-scale screening to identify subjects with CI at an early stage and allow for more intensive management aimed at stabilising it at early stages by the management of cardiovascular risk factors, and possibly of developing therapies. (English) / qualifier | |||||||||||||||
point in time: 18 November 2021
| |||||||||||||||
Revision as of 19:02, 18 November 2021
Project Q3697194 in France
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | No label defined |
Project Q3697194 in France |
Statements
600,000.0 Euro
0 references
1,012,914.0 Euro
0 references
59.24 percent
0 references
1 January 2017
0 references
31 December 2020
0 references
Institut national de la santé et de la recherche médicale (INSERM)
0 references
Une fois l’insuffisance cardiaque (IC) installée, elle est responsable d’une forte mortalité et d’hospitalisations fréquentes (première cause d’hospitalisation chez les sujets >65 ans), ainsi que de coûts sociaux et économiques très élevées. Notre équipe vise à une meilleure caractérisation du risque d'IC, tout particulièrement par des marqueurs biologiques (BM) protéiques ou ARN circulants. Le cofinancement considéré pour la présente demande est le RHU Fight-HF : il s’agit d’un programme de recherche hospitalo-universitaire (RHU) labellisé par les Investissements d’avenir PIA2 via l’ANR. Le projet Fight-HF est l’un des 4 programmes sélectionnés par le jury international lors de la première vague de cet appel d’offres national: le seul projet non parisien. La détection des formes précoces de l’IC par de simples mesures biologiques chez des participants à la Cohorte lorraine familiale Stanislas, exceptionnelle au niveau mondial (familiale, 20 ans de suivi, phénotypage cardiovasculaire de recherche) ouvrira la voie à un dépistage de grande ampleur visant à identifier les sujets présentant une IC à un stade précoce et permettre une prise en charge plus intensive visant à la stabiliser à des stades précoces par la prise en charge des facteurs de risque cardiovasculaire, et possiblement des thérapeutiques en cours de développement. (French)
0 references
Once heart failure (CI) is installed, it is responsible for high mortality and frequent hospitalisations (first cause of hospitalisation in subjects >65 years), as well as very high social and economic costs. Our team aims to improve the risk characterisation of IC, especially by protein biomarkers (BMs) or circulating RNAs. The co-financing under consideration for this application is RHU Fight-HF: it is a hospital-university research program (RHU) labeled by PIA2 Future Investments via the ANR. The Fight-HF project is one of the 4 programmes selected by the international jury during the first wave of this national call for tenders: the only non-Paris project. The detection of early forms of ICR through simple biological measurements in participants in the Stanislas Family Orraine Cohort, which is exceptional globally (family, 20 years of follow-up, cardiovascular phenopathy research) will pave the way for large-scale screening to identify subjects with CI at an early stage and allow for more intensive management aimed at stabilising it at early stages by the management of cardiovascular risk factors, and possibly of developing therapies. (English)
18 November 2021
0 references
Identifiers
LO0015651
0 references