Evaluation of the effectiveness of a surveillance system on rates of nosocomial infection in very low-weight newborns. (Q3210584): Difference between revisions
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(Created claim: summary (P836): Background: Infants of very low weight (=1500g; RNMBP) have the highest rates of nosocomial infection (IN) of all patients, with nosocomial sepsis (NS) being the most frequent and transcendent manifestation. About 25 % of them have at least one sepsis during their hospital stay. Some studies have shown that SN is preventable and that the standardisation of methods and definitions included in a monitoring system results in a significant reduction...) |
(Changed label, description and/or aliases in en: translated_label) |
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Evaluation of the effectiveness of a surveillance system on rates of nosocomial infection in very low-weight newborns. |
Revision as of 08:26, 14 October 2021
Project Q3210584 in Spain
Language | Label | Description | Also known as |
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English | Evaluation of the effectiveness of a surveillance system on rates of nosocomial infection in very low-weight newborns. |
Project Q3210584 in Spain |
Statements
47,425.0 Euro
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94,850.0 Euro
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50.0 percent
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1 January 2014
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30 September 2018
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ASOCIACION INSTITUTO DE INVESTIGACION SANITARIA BIOCRUCES
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48013
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Antecedentes: Los recién nacidos de muy bajo peso (=1500g; RNMBP) presentan las mayores tasas de infección nosocomial (IN) de todos los pacientes, siendo la sepsis nosocomial (SN) su más frecuente y trascendente manifestación. Alrededor del 25% de ellos presentan al menos una sepsis durante su estancia hospitalaria. Algunos estudios han demostrado que la SN es prevenible y que gracias a la estandarización de métodos y definiciones incluidos en un sistema de vigilancia se logra una reducción significativa en la tasa de IN. Objetivos: Evaluar la efectividad de un sistema de vigilancia epidemiológica estandarizado, estructurado y basado en la evidencia para reducir la incidencia de SN en recién nacidos de muy bajo peso atendidos en 42 UCIN participantes en el período 2014-2016. Hipótesis: La adaptación e implementación de un sistema de vigilancia de la SN para RNMBP basado en el sistema NeoKiss reducirá la tasa de SN en las UCINs participantes en el estudio. Metodología: Estudio de tipo antes y después, en el que se adaptará e implementará el sistema de vigilancia NeoKiss en 42 Unidades de Cuidados Intensivos Neonatales (UCIN) del SNS. La población a incluir será RNMBP ingresados al menos durante 72h en la UCIN y que serán seguidos hasta su alta, fallecimiento o al alcanzar los 1800g de peso. La variable principal será la incidencia de SN y/o meningitis. El análisis principal se realizará a nivel de la UCIN y de paciente. Se estimará la razón de tasas de incidencia de las variables resultado y de uso de procedimientos entre períodos. (Spanish)
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Background: Infants of very low weight (=1500g; RNMBP) have the highest rates of nosocomial infection (IN) of all patients, with nosocomial sepsis (NS) being the most frequent and transcendent manifestation. About 25 % of them have at least one sepsis during their hospital stay. Some studies have shown that SN is preventable and that the standardisation of methods and definitions included in a monitoring system results in a significant reduction in the IN rate. Objectives: Evaluate the effectiveness of a standardised, structured and evidence-based epidemiological surveillance system to reduce the incidence of SN in very low-weight infants attended in 42 NICUs participating in the 2014-2016 period. Scenario: The adaptation and implementation of an NNMBP monitoring system based on the NeoKiss system will reduce the rate of SN in the NICUs participating in the study. Methodology: Type study before and after, in which the NeoKiss surveillance system will be adapted and implemented in 42 Neonatal Intensive Care Units (NICUs) of the SNS. The population to be included will be RNMBP admitted for at least 72 hours in the NICU and will be followed until discharge, death or upon reaching 1 800 g of weight. The primary endpoint will be the incidence of SN or meningitis. The main analysis will be performed at the NICU and patient level. The ratio of incidence rates for the outcome variables and the use of procedures between periods shall be estimated. (English)
14 October 2021
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Barakaldo
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Identifiers
PI13_00587
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