Study of the influence of airway geometry on obstructive pulmonary pathologies (Q3141236): Difference between revisions
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(Created claim: summary (P836): There is a growing interest in the scientific-health community in the precise characterisation of lung morphology, both for the study of lung diseases and for their treatment through inhaled drugs. The difficulty of this study lies in the complexity of the bronchial tree, which increases exponentially with the number of levels. So far, most of the research has only managed to reach the third or fourth level, although, with the improvement of rad...) |
(Changed label, description and/or aliases in en: translated_label) |
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Study of the influence of airway geometry on obstructive pulmonary pathologies | |||
Revision as of 13:32, 12 October 2021
Project Q3141236 in Spain
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | Study of the influence of airway geometry on obstructive pulmonary pathologies |
Project Q3141236 in Spain |
Statements
27,200.0 Euro
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34,000.0 Euro
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80.0 percent
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1 January 2018
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31 March 2021
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FUNDACION PARA LA INVESTIGACION E INNOVACION BIOSANITARIA EN EL PRINCIPADO DE ASTURIAS
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43°21'38.16"N, 5°50'41.64"W
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33044
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Existe un interés creciente en la comunidad científico-sanitaria por la caracterización precisa de la morfología pulmonar, tanto para el estudio de las enfermedades pulmonares como para su tratamiento por medio de fármacos inhalados. La dificultad de este estudio reside en la complejidad del árbol bronquial, que aumenta exponencialmente con el número de niveles. Hasta el momento, la mayor parte de las investigaciones únicamente han conseguido llegar hasta el tercer o cuarto nivel, aunque, con la mejora de las técnicas radiológicas y de las simulaciones in silico , es posible llegar mucho más lejos. El objetivo principal del proyecto consiste en desarrollar modelos del pulmón que puedan usarse para predecir la progresión de enfermedades en las vías respiratorias y su respuesta al tratamiento y crear una plataforma para producir herramientas específicas para cada paciente. La metodología para alcanzar estos objetivos es la siguiente: i) Reconstrucción del árbol bronquial, ii) Determinación experimental del depósito de partículas, iii) Generación y simulación de las geometrías en modelos CFD. Semi-automatización del proceso, iv) Simulación de enfermedades pulmonares y depósito de partículas. (Spanish)
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There is a growing interest in the scientific-health community in the precise characterisation of lung morphology, both for the study of lung diseases and for their treatment through inhaled drugs. The difficulty of this study lies in the complexity of the bronchial tree, which increases exponentially with the number of levels. So far, most of the research has only managed to reach the third or fourth level, although, with the improvement of radiological techniques and simulations in silico, it is possible to go much further. The main objective of the project is to develop lung models that can be used to predict the progression of diseases in the airways and their response to treatment and to create a platform to produce patient-specific tools. The methodology for achieving these objectives is as follows: I) Reconstruction of the bronchial tree, ii) Experimental determination of particle deposition, iii) Generation and simulation of geometries in CFD models. Semi-automation of the process, iv) Simulation of lung diseases and particle deposition. (English)
12 October 2021
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Oviedo
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Identifiers
PI17_01639
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