Revision history of "New selective inhibitors of cap dependent proteins: Synthesis, delivery and characterisation" (Q84205)

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13 October 2024

  • curprev 06:2006:20, 13 October 2024DG Regio talk contribs 62,868 bytes +9 Changed label, description and/or aliases in pt
  • curprev 06:2006:20, 13 October 2024DG Regio talk contribs 62,859 bytes +54 Set a claim value: summary (P836): O projecto visa o projecto, a síntese, e a avaliação de análogos novos do tampão do mRNA 5' como inibidores selectivos de três proteínas cap-relacionadas principais: o fator de iniciação da tradução eucariótica 4E (eIF4E) e as duas enzimas de decapagem (DCPS e Dcp2). As proteínas foram seleccionadas devido a seus papéis chaves na função do mRNA e a um estado já-confirmado como alvos moleculars para o cancro e as doenças neuromusculares. Para atingir...

22 March 2024

6 July 2023

11 June 2023

24 May 2023

2 March 2023

  • curprev 22:2622:26, 2 March 2023DG Regio talk contribs 61,133 bytes −1,429 Changed label, description and/or aliases in da, sk, cs, fi, de, lv, el, sv, pt, et, bg, ro, nl, ga, hr, fr, sl, hu, es, lt, mt, and other parts

25 October 2022

20 October 2022

26 July 2022

  • curprev 03:4103:41, 26 July 2022DG Regio talk contribs 60,485 bytes +37,824 Changed label, description and/or aliases in da, el, hr, ro, sk, mt, pt, fi, sl, cs, lt, lv, bg, hu, ga, sv, et, nl, fr, de, it, es, and other parts: Adding translations: da, el, hr, ro, sk, mt, pt, fi, sl, cs, lt, lv, bg, hu, ga, sv, et,

19 January 2022

15 January 2022

16 December 2021

7 December 2021

30 November 2021

  • curprev 16:2316:23, 30 November 2021DG Regio talk contribs 14,309 bytes +2,036 Created claim: summary (P836): Le projet vise à concevoir, à synthétiser et à évaluer de nouveaux analogues de capuchon d’ARNm 5’en tant qu’inhibiteurs sélectifs de trois principales protéines liées au cap: le facteur d’initiation de la traduction eucararyotique 4E (eIF4E) et les deux enzymes de décachage (DCPS et Dcp2). Les protéines ont été sélectionnées en raison de leur rôle clé dans la fonction de l’ARNm et d’un statut déjà confirmé en tant que cibles moléculaires pour l...
  • curprev 16:2316:23, 30 November 2021DG Regio talk contribs 12,273 bytes +168 Changed label, description and/or aliases in fr: translated_label

29 October 2020

14 October 2020

  • curprev 12:3012:30, 14 October 2020DG Regio talk contribs 12,545 bytes +151 Changed label, description and/or aliases in 1 language: translated_label
  • curprev 12:3012:30, 14 October 2020DG Regio talk contribs 12,394 bytes −140 Changed label, description and/or aliases in 1 language: remove_english_label
  • curprev 12:3012:30, 14 October 2020DG Regio talk contribs 12,534 bytes +1,789 Created claim: summary (P836): The project aims at the design, synthesis, and evaluation of novel mRNA 5' cap analogs as selective inhibitors of three major cap-related proteins: the eukaryotic translation initiation factor 4E (eIF4E) and the two decapping enzymes (DCPS and Dcp2). The proteins were selected due to their key roles in mRNA function and an already-confirmed status as molecular targets for cancer and neuromuscular diseases. To achieve the goal, we propose a compr...
  • curprev 12:3012:30, 14 October 2020DG Regio talk contribs 10,745 bytes −762 Removed claim: summary (P836): The project approaches at the design, synthesis, and evaluation of novel mRNA 5’ caps as selective inhibitors of three major cage-related proteins:the eucartic translation ambiguity 4E (eIF4E) and the two decepping enzymes (DcpS and Dcp2).The proteins former due to their formal status in mRNA and neuromusculcular diseases.To achieve the good, in a comprehensive approach encompassing 1., remove_old_english_translation

9 June 2020

7 June 2020

26 March 2020

4 March 2020

  • curprev 10:0210:02, 4 March 2020DG Regio talk contribs 10,216 bytes +762 Created claim: summary (P836): The project approaches at the design, synthesis, and evaluation of novel mRNA 5’ caps as selective inhibitors of three major cage-related proteins:the eucartic translation ambiguity 4E (eIF4E) and the two decepping enzymes (DcpS and Dcp2).The proteins former due to their formal status in mRNA and neuromusculcular diseases.To achieve the good, in a comprehensive approach encompassing 1., Adding English summary

18 February 2020

8 February 2020

31 January 2020

14 January 2020