Revision history of "ERDF — UNICAEN — Co-financing of the Mcl-1 inhibitory molecules project — FONCT" (Q3673486)

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14 October 2024

  • curprev 09:2309:23, 14 October 2024DG Regio talk contribs 129,027 bytes −2 Changed label, description and/or aliases in pt
  • curprev 09:2309:23, 14 October 2024DG Regio talk contribs 129,029 bytes +74 Set a claim value: summary (P836): Os cancros do ovário continuam a ser particularmente mortais devido à sua quimiorresistência. O desenvolvimento de novas estratégias terapêuticas é, portanto, um grande desafio para melhorar a sua gestão. A nossa Unidade demonstrou anteriormente o valor da inibição concomitante de duas proteínas anti-apoptóticas da família Bcl-2, Bcl-xL e Mcl-1, para a indução da morte celular por apoptose in vitro e ex vivo (Simonin, 2009; BROTIN, 2010; Simonin, 20...

22 March 2024

7 December 2023

11 August 2022

  • curprev 12:4712:47, 11 August 2022DG Regio talk contribs 125,691 bytes +90,570 Changed label, description and/or aliases in et, lt, hr, el, sk, fi, pl, hu, cs, lv, ga, sl, bg, mt, pt, da, ro, sv, nl, fr, de, it, es, and other parts: Adding translations: et, lt, hr, el, sk, fi, pl, hu, cs, lv, ga, sl, bg, mt, pt, da, ro, sv,

13 January 2022

6 December 2021

1 December 2021

  • curprev 06:5706:57, 1 December 2021DG Regio talk contribs 20,681 bytes +4,780 Created claim: summary (P836): Ovarialkarzinomen bleiben aufgrund ihrer Chemoresistenz besonders tödlich. Die Entwicklung neuer Therapiestrategien ist daher eine große Herausforderung für die Verbesserung ihrer Behandlung.Unsere Einheit hat zuvor gezeigt, dass die gleichzeitige Hemmung zweier anti-apoptotischer Proteine der Familie Bcl-2, Bcl-xL und Mcl-1 für die Induktion des Zelltodes durch Apoptose in vitro und ex vivo von Nutzen ist (Simonin, 2009; BROTIN, 2010; Simonin,...

27 November 2021

  • curprev 12:1812:18, 27 November 2021DG Regio talk contribs 15,901 bytes −4,996 Removed claim: summary (P836): Les cancers de l’ovaire restant particulièrement meurtriers du fait de leur chimiorésistance. Le développement de nouvelles stratégies thérapeutiques constitue donc un enjeu majeur pour l‚amélioration de leur prise en charge.Notre Unité a préalablement démontré l‘intérêt de l‚inhibition concomitante de deux protéines anti-apoptotiques de la famille Bcl-2, Bcl-xL et Mcl-1, pour l‘induction de la mort cellulaire par apoptose in vitro et ex vivo...

26 November 2021

  • curprev 22:2822:28, 26 November 2021DG Regio talk contribs 20,897 bytes +4,996 Created claim: summary (P836): Les cancers de l’ovaire restant particulièrement meurtriers du fait de leur chimiorésistance. Le développement de nouvelles stratégies thérapeutiques constitue donc un enjeu majeur pour l‚amélioration de leur prise en charge.Notre Unité a préalablement démontré l‘intérêt de l‚inhibition concomitante de deux protéines anti-apoptotiques de la famille Bcl-2, Bcl-xL et Mcl-1, pour l‘induction de la mort cellulaire par apoptose in vitro et ex vivo (S...
  • curprev 14:0614:06, 26 November 2021DG Regio talk contribs 15,901 bytes +134 Changed label, description and/or aliases in de: translated_label

24 November 2021

18 November 2021

  • curprev 10:5110:51, 18 November 2021DG Regio talk contribs 15,336 bytes +144 Changed label, description and/or aliases in en: translated_label
  • curprev 10:5110:51, 18 November 2021DG Regio talk contribs 15,192 bytes +4,384 Created claim: summary (P836): Ovarian cancers remain particularly deadly because of their chemioresistance. The development of new therapeutic strategies is therefore a major challenge for improving their management. Our Unit has previously demonstrated the value of concomitant inhibition of two anti-apoptotic proteins of the Bcl-2 family, Bcl-xL and Mcl-1, for the induction of cell death by apoptosis in vitro and ex vivo (Simonin, 2009; BROTIN, 2010; Simonin, 2013) in ovari...

17 November 2021