Revision history of "Mechanistic study of biomarkers of the direct effect of acetyl salicylic acid in COX-1 and COX-2 in the development of CRC. Implications for chemoprevention." (Q3137448)

9 October 2024

• curprev 22:4322:43, 9 October 2024‎ DG Regio talk contribs‎ 77,548 bytes 0‎ ‎Changed label, description and/or aliases in pt
• curprev 22:4322:43, 9 October 2024‎ DG Regio talk contribs‎ 77,548 bytes +28‎ ‎Set a claim value: summary (P836): O ácido acetil salicílico (ASA) parece ser o candidato ideal para a quimioprevenção do cancro colorretal (CCR). Vários ensaios em andamento também visam avaliar o efeito do AAS como coterapia após o diagnóstico. Desconhecem-se os mecanismos de ação, a dose adequada e a população-alvo ideal. Demonstrámos que doses de 100 mg de AAS induzem acetilação direta, parcial mas persistente da COX-1 na mucosa colorretal normal. O objetivo primário é avaliar at...

22 March 2024

• curprev 15:1815:18, 22 March 2024‎ DG Regio talk contribs‎ 77,520 bytes +288‎ ‎Added qualifier: readability score (P590521): 0.3447384529471365

20 December 2023

• curprev 16:2416:24, 20 December 2023‎ DG Regio talk contribs‎ 77,232 bytes +7‎ ‎Changed an Item

12 June 2023

• curprev 14:1514:15, 12 June 2023‎ DG Regio talk contribs‎ 77,225 bytes +540‎ ‎Changed an Item

10 June 2023

• curprev 06:5406:54, 10 June 2023‎ Admin talk contribs‎ 76,685 bytes +437‎ BatchIngestion

17 August 2022

• curprev 19:2019:20, 17 August 2022‎ DG Regio talk contribs‎ 76,248 bytes +52,597‎ ‎Changed label, description and/or aliases in el, da, fi, mt, lv, sk, ga, cs, pt, et, hu, bg, lt, hr, sv, ro, sl, pl, nl, fr, de, it, es, and other parts: Adding translations: el, da, fi, mt, lv, sk, ga, cs, pt, et, hu, bg, lt, hr, sv, ro, sl, pl,

16 January 2022

• curprev 10:4710:47, 16 January 2022‎ DG Regio talk contribs‎ 23,651 bytes +2,691‎ ‎Changed label, description and/or aliases in it, and other parts: Adding Italian translations

17 December 2021

• curprev 09:5609:56, 17 December 2021‎ DG Regio talk contribs‎ 20,960 bytes +2,704‎ ‎Changed label, description and/or aliases in nl, and other parts: Adding Dutch translations

9 December 2021

• curprev 06:5206:52, 9 December 2021‎ DG Regio talk contribs‎ 18,256 bytes +2,672‎ ‎Changed label, description and/or aliases in de, and other parts: Adding German translations

2 December 2021

• curprev 09:2709:27, 2 December 2021‎ DG Regio talk contribs‎ 15,584 bytes +2,631‎ ‎Created claim: summary (P836): L’acide acétyl salicylique (ASA) semble être le candidat idéal pour la chimioprévention du cancer colorectal (CCR). Plusieurs essais en cours visent également à évaluer l’effet de l’AAS en tant que cothérapie après le diagnostic. Les mécanismes d’action, la dose appropriée et la population cible idéale sont inconnus. Nous avons montré que des doses de 100 mg d’AAS induisent une acétylation directe, partielle mais persistante de COX-1 dans la mu...
• curprev 09:2709:27, 2 December 2021‎ DG Regio talk contribs‎ 12,953 bytes +247‎ ‎Changed label, description and/or aliases in fr: translated_label

12 October 2021

• curprev 12:3412:34, 12 October 2021‎ DG Regio talk contribs‎ 12,706 bytes +217‎ ‎Changed label, description and/or aliases in en: translated_label
• curprev 12:3412:34, 12 October 2021‎ DG Regio talk contribs‎ 12,489 bytes +2,340‎ ‎Created claim: summary (P836): Acetyl salicylic acid (ASA) seems to be the ideal candidate for colorectal cancer chemoprevention (CCR). Several ongoing trials also aim to evaluate the effect of ASA as cotherapy after diagnosis. The mechanisms of action, the appropriate dose and the ideal target population are unknown. We have shown that doses of 100 mg of ASA induce direct, partial but persistent acetylation of COX-1 in the normal colorectal mucosa. The primary objective is...

10 October 2021

• curprev 12:3212:32, 10 October 2021‎ DG Regio talk contribs‎ 10,149 bytes +431‎ ‎Changed an Item: Edited by the materialized bot - inferring region from the coordinates

9 October 2021

• curprev 08:2808:28, 9 October 2021‎ DG Regio talk contribs‎ 9,718 bytes +499‎ ‎Changed an Item: Edited by the infer coords bot - inferring coordinates from location

7 October 2021

• curprev 22:2022:20, 7 October 2021‎ DG Regio talk contribs‎ 9,219 bytes −10‎ ‎Changed label, description and/or aliases in en
• curprev 22:2022:20, 7 October 2021‎ DG Regio talk contribs‎ 9,229 bytes +9,229‎ ‎Created a new Item